FUDMA Journal of Sciences,
Год журнала:
2024,
Номер
8(6), С. 155 - 169
Опубликована: Дек. 5, 2024
Creating
reliable,
environmentally
responsible,
and
effective
processes
that
ensure
the
traceability,
safety,
caliber
of
their
results
is
one
main
challenges
facing
researchers
doing
multi-residue
analysis.
The
QuEChERS
which
stands
for
Quick,
Easy,
Cheap,
Effective,
Rugged,
Safe
method
has
shown
itself
to
be
highly
adaptable,
yielding
positive
outcomes
with
a
range
analytes.
This
allows
versatility
in
choice
solvents,
salts,
buffers
salting-out
partitioning,
as
well
use
various
sorbents
throughout
cleanup
process.
more
friendly
sample
preparation
technique
fits
perfectly
analytical
chemistry's
rising
emphasis
on
sustainability.
review
paper's
goal
illustrate
primary
applications
method,
focus
food
environmental
investigations.
It
also
covers
important
improvements
history
methods
offers
insights
into
classes
substances
have
been
effectively
evaluated
this
methodology.
ACS Applied Materials & Interfaces,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 2, 2025
The
detection
and
quantification
of
veterinary
drug
residues
in
meat
remain
a
significant
challenge
due
to
the
complex
background
interference
inherent
matrix,
which
compromises
stability
accuracy
spectroscopic
analysis.
This
study
introduces
an
advanced
label-free
surface-enhanced
Raman
spectroscopy
(SERS)
platform
for
precise
identification
drugs.
By
employing
dual
enhancement
strategy
involving
sodium
borohydride
activation
calcium
ion-deuterium
oxide
guidance,
this
achieves
efficient
capture
signal
amplification
molecules
on
highly
active
nanoparticles.
High-quality
SERS
spectra
were
obtained
carprofen,
doxycycline
hydrochloride,
chloramphenicol,
penicillin
G
salt,
enabling
accurate
classification
suppression.
In
addition,
application
machine
learning
algorithms,
including
PCA-LDA,
heatmap,
decision
tree
modeling,
allows
differentiation
mixed
samples.
Quantitative
analyses
samples
achieved
through
intensity
ratios
multivariate
curve
resolution-alternate
least-squares
(MCR-ALS)
analysis,
with
results
showing
high
consistency
high-performance
liquid
chromatography
(HPLC)
measurements.
These
findings
highlight
potential
SERS-based
rapid
multicomponent
food
matrices.
ACS Omega,
Год журнала:
2024,
Номер
9(46), С. 45688 - 45705
Опубликована: Ноя. 7, 2024
The
detection
of
small
molecule
analytes
(SMAs)
is
great
significance
for
food
and
drug
testing,
environmental
monitoring,
disease
diagnosis.
However,
the
performance
commercially
available
SMA
immunoassays
limited
by
their
low
sensitivity
specificity
due
to
competitive
format,
leaving
significant
room
improvement.
In
recent
years,
application
noncompetitive
SMAs
has
become
a
hot
topic,
especially
with
rapid
evolution
antibody
development
technology.
remarkable
anti-immune
complex
(anti-IC)
reagents
targeting
antigen-specific
antibodies
have
garnered
interest
from
researchers
diagnostic
companies,
particularly
in
field
detection.
discovery
history
anti-IC
antibodies,
advantages
limitations
different
reagent
preparation
methods,
mechanisms
interaction
between
ICs
are
reviewed.
A
comprehensive
overview
assay,
including
pesticide
residue
detection,
mycotoxin
clinical
as
well
current
challenges
potential
solutions
immunoassays,
also
summarized
provide
reference
accurate
SMAs.
FUDMA Journal of Sciences,
Год журнала:
2024,
Номер
8(6), С. 155 - 169
Опубликована: Дек. 5, 2024
Creating
reliable,
environmentally
responsible,
and
effective
processes
that
ensure
the
traceability,
safety,
caliber
of
their
results
is
one
main
challenges
facing
researchers
doing
multi-residue
analysis.
The
QuEChERS
which
stands
for
Quick,
Easy,
Cheap,
Effective,
Rugged,
Safe
method
has
shown
itself
to
be
highly
adaptable,
yielding
positive
outcomes
with
a
range
analytes.
This
allows
versatility
in
choice
solvents,
salts,
buffers
salting-out
partitioning,
as
well
use
various
sorbents
throughout
cleanup
process.
more
friendly
sample
preparation
technique
fits
perfectly
analytical
chemistry's
rising
emphasis
on
sustainability.
review
paper's
goal
illustrate
primary
applications
method,
focus
food
environmental
investigations.
It
also
covers
important
improvements
history
methods
offers
insights
into
classes
substances
have
been
effectively
evaluated
this
methodology.
