The clinical utility of circulating tumor DNA in colorectal cancer: A narrative review DOI Creative Commons
Vijaya Lakshmi,

Meenakshi Rakesh,

M P Narmadha

и другие.

Cancer Research Statistics and Treatment, Год журнала: 2024, Номер 7(4), С. 435 - 446

Опубликована: Окт. 1, 2024

ABSTRACT Circulating free DNA (cfDNA) refers to extracellular fragments (50-200 base pairs) in the blood, released during cell apoptosis or necrosis, and linked tissue injury. Microbial cfDNA (cfmDNA), derived from bacteria, can also be present both healthy individuals patients with colorectal cancer, some species specific these categories. tumor (ctDNA), a subset of cfDNA, originates tumors reflects their genetic profile. Elevated ctDNA levels result increased death impaired clearance progression. Healthy typically have 30 ng/mL whereas cancer show up 1000 ng/mL. Patients colon often exhibit higher concentrations (500 ng/mL) compared rectal (250 ng/mL). is valuable noninvasive biomarker for monitoring progression prognosis, particularly since disease diagnosed at advanced stages. Its widespread dispersion circulating aids tracking recurrence. This article reviews life cycle, analysis methods, screening approaches, clinical applications, limitations, future perspectives ctDNA. The data this review were extracted PubMed, ScienceDirect, ResearchGate, Scopus, UpToDate, covering publications January 2016 December 2023. Out 95 retrieved articles, 3 removed before screening. Two duplicates, 1 was ineligible record. After reviewing 92 articles eligibility, 7 excluded: being non-human studies, 2 not exclusive lacking utility. We selected 85 final analysis. For purpose discussion, we referred various papers on as well ( n = 15).

Язык: Английский

Determination of multiple analytes in urine using label-free SERS coupled with simple sample pretreatments DOI
Natalia E. Markina, Alexey V. Markin

Analytica Chimica Acta, Год журнала: 2024, Номер 1332, С. 343383 - 343383

Опубликована: Ноя. 1, 2024

Язык: Английский

Процитировано

3
Raman Spectroscopy of Fullerenes: From C60 to Functionalized Derivatives DOI Creative Commons
Yifan Qin,

Jilian Xu,

Zhewen Liang

и другие.

Molecules, Год журнала: 2025, Номер 30(3), С. 738 - 738

Опубликована: Фев. 6, 2025

Fullerenes, a unique allotrope of carbon, have captured significant attention in multiple scientific fields. As non-destructive characterization technique, Raman spectroscopy has proven indispensable for investigating fullerenes and their derivatives, offering detailed insights into vibrational properties. This review discusses the broad utility revealing structural physicochemical characteristics fullerenes—from iconic C60 molecule to an array its derivatives—highlighting capacity detect functionalization-induced changes molecular structure electronic properties, while also assessing environmental influences such as solvent effects temperature variations. Particular emphasis is placed on advanced Raman-based techniques, including enhanced spectroscopy, surface-enhanced (SERS), tip-enhanced (TERS), derivatives. These cutting-edge methods offer high sensitivity ultra-high spatial resolution, greatly expanding scope fullerene research delivering deeper functional

Язык: Английский

Процитировано

0
Surface-Enhanced Raman Scattering of Bioaerosol: Where Are We Now? A Systematic Review DOI Creative Commons
Stefano Fornasaro, Sabrina Semeraro, Sabina Licen

и другие.

Chemosensors, Год журнала: 2025, Номер 13(3), С. 86 - 86

Опубликована: Март 3, 2025

Surface-enhanced Raman scattering (SERS) spectroscopy has grown in popularity as a bioaerosol monitoring method due to its high sensitivity and specificity, well ability be performed complex biological mixtures using portable relatively inexpensive devices. However, lack of standardised methodologies, SERS sensing bioaerosols remains difficult. Full-length peer-reviewed journal articles related the application examine were systematically searched PubMed, Scopus, Web Science databases PRISMA guidelines. A total 13 studies met inclusion criteria for our systematic literature search. critical evaluation experimental aspects involved collection analysis is presented, elective applicability weaknesses various setups, helping provide solid foundation real-time characterisation spectroscopy.

Язык: Английский

Процитировано

0
High-uniformity, low-cost, ultra-dense arrays of Au-capped plastic nanopillars fabricated via nanoimprint lithography as reliable SERS substrates DOI
Xuan Xue, Xiaohui Tang,

Chunrui Hu

и другие.

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Год журнала: 2025, Номер 335, С. 125989 - 125989

Опубликована: Март 5, 2025

Язык: Английский

Процитировано

0
A New Perspective on Antimicrobial Therapeutic Drug Monitoring: Surface-enhanced Raman Spectroscopy DOI
Quanfang Wang, Wei Yu, Jian‐Hui Lan

и другие.

Talanta, Год журнала: 2025, Номер unknown, С. 128017 - 128017

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0
Emerging Trends in Fluorescent and Quenching Nanomaterials for Viral detection: Innovations in Biological and Chemical sensing DOI

Deeksha Nautiyal,

Utkarsh Jain

Talanta Open, Год журнала: 2025, Номер 11, С. 100430 - 100430

Опубликована: Март 27, 2025

Язык: Английский

Процитировано

0
Characterization of corn husks carboxymethyl cellulose formation using Raman spectroscopy DOI Creative Commons
Rangsan Panyathip,

Muthita Witthayapak,

Phiphatnupong Thuephloi

и другие.

Industrial Crops and Products, Год журнала: 2025, Номер 228, С. 120887 - 120887

Опубликована: Апрель 5, 2025

Язык: Английский

Процитировано

0
AgAu@Ag core-shell triangular nanonet jointed with composite SERS enhanced substrate for capturing and sensing urine biomarkers FGFR3 and NMP22 DOI
H.M. Li,

Jian Zhu,

Guojun Weng

и другие.

Biosensors and Bioelectronics, Год журнала: 2025, Номер 286, С. 117635 - 117635

Опубликована: Май 26, 2025

Язык: Английский

Процитировано

0
Metabolite microextraction on surface-enhanced Raman scattering nanofibres and D2O probing accelerate antibiotic susceptibility testing DOI Creative Commons
Malama Chisanga, Claudèle Lemay-St-Denis, Xinran Wei

и другие.

Deleted Journal, Год журнала: 2025, Номер 2(1)

Опубликована: Июнь 2, 2025

Rapid antibiotic susceptibility tests (AST) are vital for the effective treatment of disease, necessitating development analytical tools to address unmet needs in healthcare. Leveraging sensitivity plasmonic nanosensors and isotopic labelling has potential accelerate AST. Here, we developed surface-enhanced Raman scattering (SERS)-based nanofibre sensors heavy water [deuterium oxide (D2O)] (SERS-DIP) detecting minimum inhibitory concentration (MIC) AST trimethoprim (TMP) against E. coli. SERS-DIP rapidly detected MIC TMP susceptible strain 2 h. TMP-resistant cells retained metabolic activity regardless levels, confirming resistance phenotype. Kinetic analysis D uptake by resistant treated with (2 × MIC) revealed increasing levels proportional peak redshifts over time, confirmed machine learning-driven data exploration. Our results demonstrate utility nanofibre-enabled robust AST, uncovering new spectral biomarkers that may impact clinical medicine.

Язык: Английский

Процитировано

0
The clinical utility of circulating tumor DNA in colorectal cancer: A narrative review DOI Creative Commons
Vijaya Lakshmi,

Meenakshi Rakesh,

M P Narmadha

и другие.

Cancer Research Statistics and Treatment, Год журнала: 2024, Номер 7(4), С. 435 - 446

Опубликована: Окт. 1, 2024

ABSTRACT Circulating free DNA (cfDNA) refers to extracellular fragments (50-200 base pairs) in the blood, released during cell apoptosis or necrosis, and linked tissue injury. Microbial cfDNA (cfmDNA), derived from bacteria, can also be present both healthy individuals patients with colorectal cancer, some species specific these categories. tumor (ctDNA), a subset of cfDNA, originates tumors reflects their genetic profile. Elevated ctDNA levels result increased death impaired clearance progression. Healthy typically have 30 ng/mL whereas cancer show up 1000 ng/mL. Patients colon often exhibit higher concentrations (500 ng/mL) compared rectal (250 ng/mL). is valuable noninvasive biomarker for monitoring progression prognosis, particularly since disease diagnosed at advanced stages. Its widespread dispersion circulating aids tracking recurrence. This article reviews life cycle, analysis methods, screening approaches, clinical applications, limitations, future perspectives ctDNA. The data this review were extracted PubMed, ScienceDirect, ResearchGate, Scopus, UpToDate, covering publications January 2016 December 2023. Out 95 retrieved articles, 3 removed before screening. Two duplicates, 1 was ineligible record. After reviewing 92 articles eligibility, 7 excluded: being non-human studies, 2 not exclusive lacking utility. We selected 85 final analysis. For purpose discussion, we referred various papers on as well ( n = 15).

Язык: Английский

Процитировано

0