Improved multivariate quantification of plastic particles in human blood using non-targeted pyrolysis GC-MS
Journal of Hazardous Materials,
Год журнала:
2025,
Номер
489, С. 137584 - 137584
Опубликована: Фев. 11, 2025
Accurate
analytical
methods
are
crucial
to
assess
human
exposure
micro-
and
nanoplastics
(MNPs).
Quantitative
pyrolysis-gas
chromatography
coupled
with
mass
spectrometry
(Py-GC-MS)
has
recently
been
used
for
quantifying
MNPs
in
blood.
However,
pyrolysis
introduces
complex
effects
such
as
secondary
reactions
between
matrix
compounds
polymers.
This
work
a
non-targeted
multivariate
approach
improve
the
identification
quantification
of
polyethylene
(PE),
poly(vinyl
chloride)
(PVC)
terephthalate
(PET).
After
spiking
extracted
blood
samples,
PARADISe
was
componentization
integration
417
features
detected
Py-GC-MS.
Quantification
based
on
calibration
models
demonstrated
superior
performance
when
compared
univariate
regression.
Feature
selection
approaches
were
identify
optimal
feature
subsets,
which
reduced
errors
by
30
%
PE,
10
PVC
38
PET.
In
addition,
chemical
insight
into
processes
obtained
studying
(MEs)
The
PE
appeared
be
minimally
affected
(MEs
=
81-154
%),
while
PET
exhibited
interactions
40-9031
impacting
its
accuracy.
conclusion,
this
research
highlights
importance
accounting
during
more
accurate
robust
Язык: Английский
Drinking Water Network as a Potential Pathway for Micro- and Nanoplastics Exposure to Human: A Mini Review
Water,
Год журнала:
2025,
Номер
17(8), С. 1188 - 1188
Опубликована: Апрель 15, 2025
The
risk
of
human
exposure
to
micro-
and
nanoplastics
(MNPs)
has
received
increasing
attention
in
recent
years.
Consumption
drinking
water
is
a
significant
route
MNPs.
While
previous
studies
focus
on
MNPs
treated
wastewater
or
final
effluent,
research
addressing
networks
(DWNs)
as
potential
secondary
sources
remains
sparse.
However,
how
DWN,
critical
component
transporting
from
treatment
plants
consumers,
contributes
contamination
underexplored
existing
studies.
We
extracted
keywords
reviewed
literature
using
bibliometric
methods
conducted
correlation
analyses,
revealing
four
clusters:
baseline
detection,
health
assessments,
nanoplastic,
treatment.
abundance
DWN
ranged
0.01
1.4
items/L.
varied
between
679.5
4.5
×
107
items/kg
when
calculated
based
sample
mass
(in
scales
debris).
Based
the
shape
polymer
composition
MNPs,
strongly
suspected
contribute
tap
water.
also
main
mechanisms
for
formation
release
pipelines,
including
mechanical
forces,
hammer
effects,
chemical
aging.
Our
review
highlighted
current
gaps
MNP
DWN.
It
will
understanding
contribution
provide
framework
future
monitoring
efforts.
Язык: Английский