International Journal of Molecular Sciences,
Год журнала:
2023,
Номер
25(1), С. 537 - 537
Опубликована: Дек. 30, 2023
Natural
compounds
continue
to
serve
as
the
most
fruitful
source
of
new
antimicrobials.
Analysis
bacterial
genomes
have
revealed
that
biosynthetic
potential
antibiotic
producers
by
far
exceeds
number
already
discovered
structures.
However,
due
repeated
discovery
known
substances,
it
has
become
necessary
change
both
approaches
search
for
antibiotics
and
sources
producer
strains.
The
pressure
natural
selection
diversity
interactions
in
symbiotic
communities
make
animal
microbiomes
promising
novel
substances.
Here,
microorganisms
associated
with
various
animals
were
examined
terms
their
antimicrobial
agents.
application
alternative
cultivation
techniques,
ultrahigh-throughput
screening,
genomic
analysis
facilitated
investigation
produced
unique
representatives
microbiota.
We
believe
strategies
antipathogen
defense
will
be
precisely
studying
cell–cell
host–microbe
wild.
Journal of Cosmetic Dermatology,
Год журнала:
2025,
Номер
24(1)
Опубликована: Янв. 1, 2025
ABSTRACT
Background
Scalp
itch
without
evident
cause
is
an
uncomfortable
symptom
that
annoys
many
people
in
life
but
lacks
adequate
attention
academic.
Aims
To
investigate
the
relationship
between
scalp
itching
and
microorganisms,
identify
key
microbes
predicted
functions
associated
with
itching,
furtherly
to
provide
useful
targets
for
solution.
Methods
We
performed
microbial
comparison
44
normal
subjects
89
having
problem
un‐identified
origin
based
on
16S
rRNA
gene
sequencing
ddPCR
(digital
droplet
PCR),
identified
relevant
functions.
minimize
false
positive
findings,
another
43
itchy
were
used
independent
validation.
Results
The
three
most
abundant
bacterial
genus
Cutibacterium
,
Lawsonella,
Staphylococcus
predominant
fungi
Malassezia
not
significantly
different
subjects,
imbalance
occurred
scalp.
As
function
contributor
community,
various
ASVs
(amplicon
sequence
variants)
detected
or
low
abundance
subject
specific.
Some
non‐resident
from
environment
such
as
Leptolyngbya
ANT.L52.2
Pseudomonas
enhanced
occupied
important
ecological
niche.
severity
of
was
alleviated
when
these
coverage
reduced
diminished.
Conclusions
Our
findings
raise
(1)
ratio
(2)
bacteria
scalp,
potential
solutions
ease
itch.
Environmental Microbiology,
Год журнала:
2025,
Номер
27(1)
Опубликована: Янв. 1, 2025
ABSTRACT
Active
geothermal
systems
are
relatively
rare
in
Antarctica
and
represent
metaphorical
islands
ideal
to
study
microbial
dispersal.
In
this
study,
we
tested
the
macro‐ecological
concept
that
high
dispersal
rates
result
communities
being
dominated
by
either
habitat
generalists
or
specialists
investigating
on
four
geographically
separated
sites
three
Antarctic
volcanoes
(Mts.
Erebus,
Melbourne,
Rittman).
We
found
at
higher
temperature
(max
65°C)
(Tramway
Ridge
Erebus
Rittmann)
were
unique
from
each
other
a
variety
of
novel
Archaea
class
Nitrososphaeria
,
while
lower
50°C)
(Western
Crater
Melbourne)
had
characteristically
mesophilic
(
Planctomycetes,
Acidobacteriota,
etc.)
highly
similar.
97%
detected
taxa
regional
specialists,
with
no
generalists,
community
assembly
driven
drift
(25%
30%
assembly,
respectively),
not
environmental
selection.
Our
results
indicate
for
experiencing
between
isolated
communities,
may
tend
out‐compete
generalists.
Nutrition Reviews,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 15, 2025
Abstract
The
field
of
precision
nutrition
aims
to
develop
dietary
approaches
based
on
individual
biological
factors
such
as
genomics
or
the
gut
microbiota.
microbiota,
which
is
highly
individualized
and
complex
community
microbes
residing
in
colon,
a
key
contributor
human
physiology.
Although
play
multiple
roles
metabolism
nutrients,
their
role
modulating
absorption
energy
from
foods
that
escape
digestion
small
intestine
has
potential
variably
affect
balance
and,
thus,
body
weight.
fate
this
energy,
its
subsequent
impact
weight,
well
described
rodents
emerging
humans.
This
narrative
review
focused
recent
clinical
evidence
microbiota
balance,
specifically
available
host.
Despite
progress,
remaining
gaps
knowledge
present
opportunities
for
developing
implementing
strategies
understand
causal
microbial
mechanisms
related
balance.
We
propose
rigorous
microbiota-focused
measurements
context
innovative
trial
designs
will
elucidate
integrated
diet-host-gut
mechanisms.
These
are
primed
be
targets
interventions
optimize
achieve
desired
weight
outcomes.
Given
magnitude
obesity
epidemic,
these
within
comprehensive
management
paradigms
public
health
significance.
