Опубликована: Янв. 1, 2024
Язык: Английский
Proceedings of the National Academy of Sciences, Год журнала: 2025, Номер 122(4)
Опубликована: Янв. 22, 2025
The emerging new generation of small-scaled acoustic microrobots is poised to expedite the adoption microrobotics in biomedical research. Recent designs these have enabled intricate bioinspired motions, paving way for their real-world applications. We present a multiorifice design air-filled spherical that convert wave energy efficient propulsion through resonant encapsulated microbubble. These can swim boundary-free three-dimensional (3D) space while switching between various frequency-dependent locomotion modes. explore dynamics with diameters ranging from 10 μm 100 μm, focusing on 3D swimming and multimodal response stimuli below 1 MHz. Further, we elucidate microrobots, featuring single cavity, which contributes complex streaming facilitates swift, unrestricted movements. Finally, demonstrate incorporating additional nickel gold layers significantly enhances steering visibility optoacoustic ultrasound imaging, enabling development next healthcare
Язык: Английский
Процитировано
1
Materials & Design, Год журнала: 2025, Номер unknown, С. 113827 - 113827
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
1
EAI Endorsed Transactions on AI and Robotics, Год журнала: 2024, Номер 3
Опубликована: Апрель 12, 2024
Micro robots, miniature robotic devices typically ranging from micrometers to a few millimeters in size, hold immense potential various fields, particularly healthcare. Their diminutive stature enables access intricate anatomical regions previously unreachable, facilitating targeted drug delivery, localized treatment, and precise monitoring. These robots offer numerous advantages, including enhanced maneuverability, reduced invasiveness, minimized tissue damage. By navigating through complex biological environments, micro can deliver therapies with unprecedented precision, improving treatment efficacy patient outcomes. Additionally, their small size allows for minimally invasive procedures, reducing recovery times enhancing comfort. Overall, represent groundbreaking technological advancement the revolutionize healthcare delivery significantly benefit human well-being.Their Despite challenges like constraints navigation complexities, innovative solutions interdisciplinary collaboration are driving
Язык: Английский
Процитировано
6
Advanced Healthcare Materials, Год журнала: 2024, Номер unknown
Опубликована: Окт. 7, 2024
Abstract Biohybrid micro/nanorobots hold a great potential for advancing biomedical research. These tiny structures, designed to mimic biological organisms, offer promising method targeted drug delivery, tissue engineering, biosensing/imaging, and cancer therapy, among other applications. The integration of biology robotics opens new possibilities minimally invasive surgeries personalized healthcare solutions. key challenges in the development biohybrid include ensuring biocompatibility, addressing manufacturing scalability, enhancing navigation localization capabilities, maintaining stability dynamic environments, navigating regulatory hurdles, successfully translating these innovative technologies into clinical Herein, recent advancements, challenges, future perspectives related applications are described. Indeed, this review sheds light on cutting‐edge developments field, providing researchers with an updated overview current realm applications, offering insights their practical Furthermore, it delves advancements field micro/nanorobotics, comprehensive analysis state‐of‐the‐art field.
Язык: Английский
Процитировано
6
Frontiers in Chemistry, Год журнала: 2024, Номер 12
Опубликована: Май 22, 2024
Recent years have witnessed a surge in the application of microrobots within medical sector, with hydrogel standing out due to their distinctive advantages. These microrobots, characterized by exceptional biocompatibility, adjustable physico-mechanical attributes, and acute sensitivity biological environments, emerged as pivotal tools advancing applications such targeted drug delivery, wound healing enhancement, bio-imaging, precise surgical interventions. The capability navigate perform tasks complex systems significantly enhances precision, efficiency, safety therapeutic procedures. Firstly, this paper delves into material classification properties compares advantages different materials. Furthermore, it offers comprehensive review principal categories recent innovations synthesis, actuation mechanisms, biomedical hydrogel-based microrobots. Finally, manuscript identifies prevailing obstacles future directions microrobot research, aiming furnish insights that could propel advancements field.
Язык: Английский
Процитировано
5
International Journal of Extreme Manufacturing, Год журнала: 2024, Номер 6(6), С. 062006 - 062006
Опубликована: Авг. 21, 2024
Abstract Micro/nanorobots (MNRs) capable of performing tasks at the micro- and nanoscale hold great promise for applications in cutting-edge fields such as biomedical engineering, environmental microfabrication. To cope with intricate dynamic environments encountered practical applications, development high performance MNRs is crucial. They have evolved from single-material, single-function, simple structure to multi-material, multi-function, complex structure. However, design manufacturing multi-material three-dimensional structures pose significant challenges that cannot be addressed by conventional serial strategies single-process methods. The material-interface-structure-function/ coupled methods additive/formative/subtractive composite offer opportunity manufacture multi-materials under multi-factor coupling, thus paving way MNRs. In this paper, we take three core capabilities MNRs—mobility, controllability, load capability—as focal point, emphasizing oriented towards their function/performance functional structures. limitations current investigation are also discussed, our envisioned future directions shared. We hope review will provide a framework template MNRs, serving roadmap researchers interested area.
Язык: Английский
Процитировано
5
Frontiers in Chemistry, Год журнала: 2025, Номер 13
Опубликована: Фев. 6, 2025
In recent years, medical micro-/nanorobots (MNRs) have emerged as a promising technology for diagnosing and treating malignant tumors. MNRs enable precise, targeted actions at the cellular level, addressing several limitations of conventional cancer diagnosis treatment, such insufficient early diagnosis, nonspecific drug delivery, chemoresistance. This review provides an in-depth discussion propulsion mechanisms MNRs, including chemical fuels, external fields (light, ultrasound, magnetism), biological propulsion, hybrid methods, highlighting their respective advantages limitations. Additionally, we discuss novel approaches tumor precision surgery, emphasizing potential clinical applications. Despite significant advancements, challenges biocompatibility, efficiency, translation persist. examines current state MNR applications outlines future directions development, with aim enhancing diagnostic therapeutic efficacy facilitating integration into practice.
Язык: Английский
Процитировано
0
Advanced Engineering Materials, Год журнала: 2025, Номер unknown
Опубликована: Фев. 21, 2025
To overcome the propulsion difficulties in low Reynolds number environment, natural species have developed their exclusive swimming strategies after 1000 years of evolution. Inspired by those fascinating creatures, diverse artificial microrobots are proposed to achieve distinctive biomimetic motions. However, lack cognition for mechanism hinders exploration multimode biomimicking microrobots, especially at high‐speed locomotion. Herein, behaviors micro sonobot featured with multiple‐layer tubular constructions and trapped microbubbles serving as powerful microengines reported. The observed speed achieves tens millimeters per second. Different from previously reported bubble‐loaded it is that primary Bjerknes forces originating nonhomogeneous acoustic field make a great contribution orientation. Along streaming secondary forces, including individual locomotion group aggregation emerged theoretically analyzed. motion sonobots offers marvelous potentials building multifunctional micro/nanosystems nanosurgery, lab‐on‐a‐chip biosystems, chemical biological engineering, environmental detoxification, etc.
Язык: Английский
Процитировано
0
Nanoscale, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
Biohybrid microrobot (Spirulina, Fe 3 O 4 , ZIF-8) rapidly adsorbs organic pollutants and navigates narrow gaps directionally via magnetic steering.
Язык: Английский
Процитировано
0
ACS Sustainable Chemistry & Engineering, Год журнала: 2025, Номер unknown
Опубликована: Март 6, 2025
Язык: Английский
Процитировано
0