Mixture Design and Doehlert Matrix for Optimization of Energized Dispersive Guided Extraction (EDGE) of Theobromine and Caffeine from Cocoa Bean Shells

Foods, Год журнала: 2025, Номер 14(5), С. 740 - 740

Опубликована: Фев. 21, 2025

This work describes the development of a method for extraction methylxanthines from cocoa bean shell (CBS) by employing novel Energized Dispersive Guided Extraction (EDGE) system. The mixtures were composed ethanol-methanol-water and ratio was optimized using simplex-centroid design. Doehlert design (DD) used to optimize variables temperature time while methylxanthine content obtained HPLC-DAD as an analytical response. mixture consisted water-ethanol in 3:2 ratio. optimum operating conditions achieved at 148.5 °C 382 s. Under optimal conditions, 20.14 mg g-1 DM theobromine 3.53 caffeine found CBS extract. Methylxanthines quantified with good linearity, LOQs, LODs, precision, accuracy. EDGE system, newly automated instrument, has proven be very efficient recovery caffeine, is considered green procedure, demonstrated greenness metric sample preparation.

Язык: Английский

Optimization of the effect of cold plasma treatment on UAE-NADES green extraction of chickpea roots (Cicer arietinum) bioactive compounds

Ultrasonics Sonochemistry, Год журнала: 2025, Номер 114, С. 107276 - 107276

Опубликована: Фев. 22, 2025

Язык: Английский

Influence of ultrasound-assisted extraction of bioactives from garlic (Allium sativum) sprouts using response surface methodology

Ultrasonics Sonochemistry, Год журнала: 2025, Номер 115, С. 107286 - 107286

Опубликована: Фев. 25, 2025

Язык: Английский