Chinese Medicine, Год журнала: 2025, Номер 20(1)
Опубликована: Апрель 9, 2025
Abstract Lignans derived from Schisandra chinensis have attracted significant attention for their diverse pharmacological activities and clinical potential. This review presents a comprehensive analysis of the properties lignans, including antioxidant, anti-inflammatory, neuroprotective, hepatoprotective, antibacterial/viral, antidiabetic anticancer effects. Their multifaceted mechanisms action hold promise therapeutic areas such as cancer, neurodegenerative diseases metabolic disorders, aligning with urgent needs. Additionally, this explores pharmacokinetics these bioactive compounds, highlighting challenges in absorption, distribution, metabolism excretion, which impact bioavailability. Recent advancements drug delivery systems are discussed, potential to enhance efficacy settings. Furthermore, synergistic effects combining lignans other agents considered strategy increase efficacy. Future research is imperative identify additional active components elucidate novel action, paving way expanded applications unlocking full disease prevention treatment.
Язык: Английский