medRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2023,
Номер
unknown
Опубликована: Июль 27, 2023
Abstract
Background
and
aim
Vaccine
uptake
within
the
Dutch
National
Immunisation
Programme
(NIP)
has
slightly
declined
since
COVID-19
pandemic.
We
studied
psychosocial
factors
of
vaccine
uptake,
namely
parental
intention,
attitudes,
beliefs,
trust
deliberation
(i.e.,
self-evidence),
before
(2013)
two
years
into
pandemic
(2022).
Methods
In
2022
2013,
parents
with
a
young
child
(aged
<3.5
years)
participated
in
online
surveys
on
vaccination
(n=1,000
800,
(estimated)
response=12.2%
37.2%,
respectively).
Psychosocial
were
measured
7-point
Likert
scales.
Multivariate
logistic
regression
analysis
was
used
to
study
differences
between
2013
‘negative’
scores
(≤2)
factors.
Results
both
most
expressed
positive
intention
(2022=83.1%,
2013=87.0%),
attitudes
(3
items:
2022=66.7%-70.9%,
2013=62.1%-69.8%)
(2022=51.8%,
2013=52.0%)
towards
NIP
felt
that
vaccinating
their
self-evident
(2022=57.2%,
2013=67.3%).
Compared
had
significantly
higher
odds
reporting
negative
items
combined:
OR=2.84),
believing
vaccinations
offer
insufficient
protection
(OR=4.89),
is
not
beneficial
for
child’s
health
(OR=2.23),
does
necessarily
protect
other
children
(OR=2.24)
or
adults
(OR=2.22)
could
cause
severe
side
effects
(OR=2.20),
preferring
natural
infection
over
(OR=3.18)
low
(OR=1.73).
Conclusions
Although
perceived
as
self-evident,
proportions
larger
compared
2013.
Monitoring
these
determinants
developing
appropriate
interventions
contribute
sustaining
high
uptake.
Human Vaccines & Immunotherapeutics,
Год журнала:
2023,
Номер
19(2)
Опубликована: Авг. 1, 2023
Declining
trends
in
vaccine
confidence
come
at
a
time
when
routine
immunization
coverage
for
children
has
slumped
to
decades-long
low.
With
some
of
the
largest
losses
experienced
among
young
adults,
this
is
concerning
trend
with
potential
long-term
implications.
This
article
reflects
on
recent
research
examining
levels
and
over
across
globe,
drivers
influencing
confidence,
role
COVID-19
pandemic
shaping
today.
Timely
examination
causes
consequences
waning
critical
evaluation
response
measures
will
prove
vital
mitigating
additional
uptake
while
contributing
building
resilience
face
future
health
crises.
Vaccine,
Год журнала:
2023,
Номер
41(20), С. 3178 - 3188
Опубликована: Апрель 4, 2023
In
the
wake
of
mass
COVID-19
vaccination
campaigns
in
2021,
significant
differences
vaccine
skepticism
emerged
across
Europe,
with
Eastern
European
countries
particular
facing
very
high
levels
hesitancy
and
refusal.
This
study
investigates
determinants
refusal,
a
focus
on
these
Eastern,
Southern
Western
Europe.
The
statistical
analyses
are
based
individual-level
survey
data
comprising
quota-based
representative
samples
from
27
May
2021.
finds
that
demographic
variables
have
complex
associations
relationships
age
education
non-linear.
Trust
different
sources
health-related
information
has
as
well,
people
who
trust
Internet,
social
networks
'people
around'
being
much
more
likely
to
express
skepticism.
Beliefs
safety
effectiveness
vaccines
large
predictive
power.
Importantly,
this
shows
demographic,
belief-related
other
factors
refusal
context-specific.
Yet,
explanations
Europe
need
why
vaccine-relevant
beliefs
differ
regions,
because
effects
appear
be
similar.
It
is
higher
prevalence
such
distrust
national
governments
medical
processionals
relevant
for
explaining
observed
region.
Vaccine,
Год журнала:
2024,
Номер
42(4), С. 801 - 811
Опубликована: Янв. 12, 2024
Vaccine
uptake
within
the
Dutch
National
Immunisation
Programme
(NIP)
has
slightly
declined
since
COVID-19
pandemic.
We
studied
psychosocial
factors
of
vaccine
uptake,
namely
parental
intention,
attitudes,
beliefs,
trust
and
deliberation
(i.e.,
self-evidence),
before
(2013)
two
years
into
pandemic
(2022).
Abstract
The
current
study
sought
to
determine
whether
public
perceptions
of
other
vaccines
and
diseases
than
COVID-19
have
been
impacted
by
the
pandemic.
We
longitudinally
examined
there
had
a
change
from
before
pandemic
during
in:
(a)
influenza
vaccination
behaviour
intentions;
(b)
perceived
benefit
childhood
vaccines;
(c)
safety
(d)
severity
measles
influenza;
(e)
trust
in
healthcare
professionals
two
samples
Finnish
adults
(
N
=
205
Study
1
197
2).
findings
showed
that
pandemic,
more
people
received
or
wanted
receive
vaccine.
respondents
also
believed
was
dangerous
vaccinations
were
safer
beneficial.
On
hand,
for
only
increased.
Finally,
one
studies,
confidence
medical
they
before.
Together,
these
imply
spillover
on
how
view
illnesses.
Journal of Travel Medicine,
Год журнала:
2023,
Номер
30(4)
Опубликована: Апрель 19, 2023
Many
travellers
do
not
receive
vaccines
pre-travel.
Tools
such
as
vaccine
decision
aids
could
support
informed
decision-making.
We
aimed
to
characterise
Australians'
pre-travel
attitudes,
behaviours
and
information
needs
examine
the
role
for
in
travel
medicine.
Vaccines,
Год журнала:
2024,
Номер
12(5), С. 458 - 458
Опубликована: Апрель 25, 2024
Background:
Routine
vaccination
coverage
in
Latin
America
and
the
Caribbean
declined
prior
to
during
coronavirus
pandemic.
We
assessed
pandemic’s
impact
on
national
levels
analyzed
whether
financial
inequality
indicators,
immunization
policies,
pandemic
policies
were
associated
with
changes
regional
levels.
Methodology:
compared
first-
third-dose
of
diphtheria–pertussis–tetanus-containing
vaccine
(DTPcv)
predicted
coverages
using
time
series
forecast
modeling
for
39
LAC
countries
territories.
Data
from
PAHO/WHO/UNICEF
Joint
Reporting
Form.
A
secondary
analysis
factors
hypothesized
affect
was
also
performed.
Results:
In
total,
31
territories
(79%)
had
greater-than-predicted
declines
DTPcv1
DTPcv3
pandemic,
9
12
these,
respectively,
falling
outside
95%
confidence
interval.
Within-country
income
(i.e.,
Gini
coefficient)
significant
coverage,
cross-country
coverages.
Observed
absolute
relative
gaps
between
extreme
country
quintiles
Q1
vs.
Q5)
accentuated
2021,
as
2019
observed
2021
values.
a
trend
school
closures
that
approached
statistical
significance
(p
=
0.06).
Conclusion:
The
exposed
inequities
significantly
impacted
many
countries.
New
strategies
are
needed
reattain
high
Human Vaccines & Immunotherapeutics,
Год журнала:
2025,
Номер
21(1)
Опубликована: Янв. 23, 2025
The
COVID-19
pandemic
has
significantly
altered
public
perceptions
of
vaccines,
particularly
among
parents.
In
high-income
countries
like
the
United
Kingdom
(UK)
and
Australia,
factors
such
as
misinformation,
expedited
approval
process
vaccines
unique
local
challenges
have
contributed
to
vaccine
hesitancy,
resulting
in
uneven
uptake
across
various
vaccination
programs.
Despite
efforts
school-based
influenza
programs
UK
free
rates
continue
decline.
This
is
especially
concerning
given
concurrent
circulation
during
winter
months,
which
places
additional
strain
on
healthcare
systems.
Drawing
existing
evidence,
this
commentary
examines
key
influencing
childhood
provides
preliminary
policy
recommendations
address
these
challenges.
Three
actionable
are
outlined,
including
strategies
counter
improve
accessibility,
strengthen
trust
These
insights
aim
guide
development
effective
interventions
increase
uptake.
AIDS and Behavior,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 10, 2025
Abstract
Vaccine
hesitancy
is
a
leading
threat
to
public
health,
but
little
known
about
the
beliefs
and
mindsets
that
drive
vaccine
hesitancy,
especially
among
people
of
Black
ethnicities.
This
study
aimed
understand
related
their
relationship
with
SARS-CoV-2
uptake
in
UK
residents
ethnicities
living
HIV.
Adults
self-reported
HIV
were
recruited
at
12
clinics
England.
Participants
completed
questionnaires
clinic,
including
an
adapted
version
Beliefs
Medicines
Questionnaire
(BMQ)
assess
Necessity
Concerns
vaccine.
vaccination
status
was
ascertained
through
self-report
shared
care
records.
A
total
863
participants
enrolled
between
June
2021
October
2022,
most
whom
(92%)
had
received
least
one
dose
SARS
CoV-2
After
adjusting
for
age
region
birth,
higher
perceived
need
(OR
=
2.39,
95%
CI
1.51–3.81),
fewer
concerns
0.16,
0.08–0.30),
weaker
endorsement
COVID-19
Conspiracy
0.31,
0.19–0.50)
associated
uptake.
Being
born
outside
sub-Saharan
Africa
reduced
odds
being
vaccinated.
shows
importance
specific
driving
Further
studies
should
explore
role
these
influencing
other
vaccinations,
work
key
stakeholders
how
address
improve
populations.
Background:
Compared
to
other
groups
of
Canadians,
Black
people
have
been
significantly
more
affected
by
COVID-19
and
appear
be
hesitant
receive
the
vaccine.
This
article
identifies
approaches
or
strategies
increase
vaccine
confidence
uptake
among
in
Canada.
Methods:
Thirty-six
diverse
ethnicities,
aged
18
years
above,
living
six
provinces
across
Canada
were
interviewed.
An
inductive
thematic
approach
was
employed
analyze
interview
data.
Results:
Building
trust
at
center
identified
spoke
meaningful
practical
ways
sociocultural
realities
can
used
inform
implement
most
effective
health
interventions.
Identified
include
public
education,
building
through
Black-led
community
engagement,
addressing
barriers
convenience
focusing
on
literacy
communication.
Together,
these
consider
nuance
message,
diversity
messenger(s),
communication
channels
call
for
a
move
away
from
generic
promotion
messages
tailored
communications
grounded
expertise
experiences
all
levels
healthcare
service
provision.
Conclusions:
Health
must
acknowledge
difference,
tailor
target
audiences,
foster
lasting
collaborations
informed
members
community.
Government
agencies
providers
should
relationships
established
during
pandemic,
document
lessons
learned,
remove
systemic
healthcare,
create
an
emergency
preparedness
guide
engagement
Vestnik,
Год журнала:
2025,
Номер
1(72), С. 43 - 57
Опубликована: Март 25, 2025
Введение.
Корь
у
беременных
представляет
значительную
угрозу
для
здоровья
матери
и
плода.
Снижение
коллективного
иммунитета
отказ
от
вакцинации
приводят
к
вспышкам
заболевания
даже
в
развитых
странах,
а
физиологические
изменения
иммунной
системе
увеличивают
риск
осложнений,
таких
как
выкидыши,
преждевременные
роды
врожденные
аномалии.
Цель
исследования.
Описать
клинические
особенности
течения
кори
период
эпидемического
подъема.
Материалы
методы
В
исследовании
проанализированы
медицинские
карты
63
пациенток,
госпитализированных
Областную
клиническую
инфекционную
больницу
во
время
подъема
заболеваемости
корью
Актюбинской
области.
Анализ
включал
данные
о
жалобах,
клинических
проявлениях,
лабораторных
инструментальных
исследованиях
с
расчетом
процентных
соотношений
по
каждому
показателю.
Результаты.
Распределение
возрасту
показало:
46%
–
20
до
30
лет,
старше
лет
8%
младше
лет.
Все
пациентки
были
привиты
против
детстве,
однако
повторной
взрослом
возрасте
отсутствовали.
Тяжёлые
формы
30%,
средние
67%,
лёгкие
3%.
Большинство
пациенток
(76,2%)
находились
стационаре
6–8
дней,
остальные
менее
5
или
более
8
дней.
Классические
симптомы
кори:
высокая
температура
(38,5–40°C)
на
3–5
ярко
выраженный
катаральный
кашлем,
ринитом,
конъюнктивитом,
пятна
Бельского-Филатова-Коплика
(100%)
типичное
распространение
сыпи.
Бронхит
выявлен
12,7%
(из
них
обструктивным
типом
37,5%),
пневмония
11,1%
(с
одышкой
риском
дыхательной
недостаточности),
диарея
4,8%,
выкидыш
1
случае,
энцефалит
не
зарегистрирован.
Отмечены
лейкопения
(23,8%),
относительный
лимфоцитоз
(74,6%),
нейтрофилез
(79,4%),
повышенная
СОЭ
(84,1%),
анемия
(92,1%)
тромбоцитопения
(14,3%).
При
тяжёлом
течении
выраженные
печеночных
ферментов.
Выводы.
протекает
тяжело,
30%
случаев
характеризующихся
выраженной
интоксикацией
высокой
лихорадкой.
Наблюдались
признаки
выраженного
воспалительного
процесса
лейкопения,
цитолиз
гепатоцитов.
Кіріспе.
Жүкті
әйелдердегі
қызылша
ана
мен
ұрықтың
денсаулығына
айтарлықтай
қауіп
төндіреді.
Ұжымдық
иммунитеттің
төмендеуі
және
вакцинациялаудан
бас
тарту
тіпті
дамыған
елдерде
де
аурудың
өршуіне
әкеледі,
ал
иммундық
жүйедегі
физиологиялық
өзгерістер
төлдеу,
мерзімінен
бұрын
босану
туа
біткен
ауытқулар
сияқты
асқыну
қаупін
арттырады.
Зерттеу
мақсаты.
Эпидемиялық
көтерілу
кезеңінде
жүкті
әйелдердің
ағымының
клиникалық
ерекшеліктерін
сипаттау.
материалдары
әдістері.
Зерттеуде
Ақтөбе
облысында
қызылшамен
сырқаттанушылықтың
артуы
кезінде
Облыстық
жұқпалы
аурулар
ауруханасына
жатқызылған
пациенттің
медициналық
картасы
талданды.
Талдау
әрбір
көрсеткіш
бойынша
пайыздық
арақатынасты
есептей
отырып,
шағымдар,
көріністер,
зертханалық
аспаптық
зерттеулер
туралы
деректерді
қамтыды.
Нәтижелер.
Жасы
бөлу:
-
20-дан
жасқа
дейін,
жастан
жоғары
төмен.
Барлық
науқастар
балалық
шақта
қызылшаға
қарсы
егілген,
бірақ
ересек
жаста
қайта
егу
деректер
жоқ.
Ауыр
түрлері
орташа
өкпесі
Пациенттердің
көпшілігі
стационарда
6-8
күн,
қалғандары
немесе
күннен
аз
болды.
Қызылшаның
классикалық
белгілері:
3-5
күнге
(38,5-40
°
C),
жөтелмен,
ринитпен,
конъюнктивитпен,
Бельский-Филатов-Коплик
дақтарымен
анық
білінетін
катаралдық
кезең
бөртпенің
типтік
таралуы.
(оның
ішінде
обструктивті
типпен
(демігу
тыныс
алу
жетіспеушілігі
қаупімен),
түсік
тастау
жағдайда
анықталған,
тіркелген
Лейкопения
салыстырмалы
(14,3%)
белгіленді.
ағымда
айқын
өзгерістер.
Қорытынды.
қызылшасы
ауыр,
-ды
интоксикациямен
қызбамен
сипатталады.
Айқын
қабыну
процесінің
белгілері
гепатоциттердің
цитолизі
байқалды
.
Introduction.
Measles
in
pregnant
women
poses
a
significant
threat
to
maternal
and
fetal
health.
Decreased
collective
immunity
failure
vaccinate
lead
outbreaks
even
developed
countries,
physiological
changes
the
immune
system
increase
risk
of
complications
such
as
miscarriage,
preterm
birth
congenital
anomalies.
Objective
study.
To
describe
clinical
features
course
measles
during
epidemic
rise.
Materials
methods
Medical
records
patients
hospitalized
at
Regional
Clinical
Infectious
Diseases
Hospital
upsurge
Aktobe
Oblast
were
analyzed
The
analysis
included
data
on
complaints,
manifestations,
laboratory
instrumental
investigations
with
calculation
percentages
for
each
indicator.
Results.
Age
distribution
showed:
years
old,
older
than
old
younger
old.
All
immunized
against
childhood,
but
there
no
re-immunization
adulthood.
Severe
forms
moderate
mild
Most
(76.2%)
days,
while
rest
less
or
more
days.
classic
symptoms
high
fever
(38.5-40°C)
pronounced
catarrhal
period
cough,
rhinitis,
conjunctivitis,
Belsky-Filatov-Koplik
spots
typical
rash.
Bronchitis
was
detected
12.7%
(including
obstructive
type
37.5%),
pneumonia
11.1%
(with
dyspnea
respiratory
failure),
diarrhea
4.8%,
miscarriage
case,
encephalitis
not
registered.
Leukopenia
(23.8%),
relative
lymphocytosis
(74.6%),
neutrophilosis
(79.4%),
elevated
SLE
(84.1%),
anemia
(92.1%)
thrombocytopenia
(14.3%)
noted.
In
severe
marked
liver
enzymes.
Conclusions.
runs
severely,
cases
characterized
by
intoxication
fever.
Signs
inflammatory
process
leukopenia,
cytolysis
hepatocytes
observed.