Monitoring Biochemical Changes of Neuroblastoma Cells in Early Stages After X-Ray Exposure by Using Fourier-Transform Infrared Spectroscopy DOI Creative Commons
Rosario Esposito, Marianna Portaccio, Roberta Meschini

и другие.

Sensors, Год журнала: 2024, Номер 24(23), С. 7459 - 7459

Опубликована: Ноя. 22, 2024

X-ray radiation treatments are largely adopted in radiotherapy, and Fourier-transform infrared microspectroscopy (μ-FTIR) has already been demonstrated to be a useful instrument for monitoring radiotherapy effects. Previous works this field have focused on studying the changes occurring cells when they fixed immediately after irradiation or 24 48 h later. In present paper, SH-SY5Y neuroblastoma first hours examined obtain information processes taking place not-yet-investigated time window by using μ-FTIR. For purpose, cell samples were exposure, 2 4 investigated along with unexposed cells. Different data analysis procedures implemented estimate lipid, protein, DNA spectral contributions. The investigation effects of exposure is helpful better describing that offer possibility timely check efficacy can potentially applied planning personalized treatment as required most advanced medical therapy.

Язык: Английский

Monitoring Biochemical Changes of Neuroblastoma Cells in Early Stages After X-Ray Exposure by Using Fourier-Transform Infrared Spectroscopy DOI Creative Commons
Rosario Esposito, Marianna Portaccio, Roberta Meschini

и другие.

Sensors, Год журнала: 2024, Номер 24(23), С. 7459 - 7459

Опубликована: Ноя. 22, 2024

X-ray radiation treatments are largely adopted in radiotherapy, and Fourier-transform infrared microspectroscopy (μ-FTIR) has already been demonstrated to be a useful instrument for monitoring radiotherapy effects. Previous works this field have focused on studying the changes occurring cells when they fixed immediately after irradiation or 24 48 h later. In present paper, SH-SY5Y neuroblastoma first hours examined obtain information processes taking place not-yet-investigated time window by using μ-FTIR. For purpose, cell samples were exposure, 2 4 investigated along with unexposed cells. Different data analysis procedures implemented estimate lipid, protein, DNA spectral contributions. The investigation effects of exposure is helpful better describing that offer possibility timely check efficacy can potentially applied planning personalized treatment as required most advanced medical therapy.

Язык: Английский

Процитировано

1