Distinct Distribution of HEV-3 Subtypes across Humans, Animals, and Environmental Waters in Sweden

Emerging Microbes & Infections, Год журнала: 2025, Номер unknown

Опубликована: Апрель 1, 2025

We previously observed a notable discrepancy in the distribution of HEV-3 subtypes between wastewater and clinical samples Sweden. To confirm this observation comprehensively elucidate circulation patterns across humans, animals, environmental waters Sweden, we analyzed HEV genetic diversity archived late 2016 early 2018, cases 2012 2024, all available Swedish sequences from NCBI Virus database. RNA was detected samples, with subtype 3c being only identified. In typed cases, 3f (45/126) (44/126) were nearly equally distributed, though regional dominance varied. When incorporating human other studies, became dominant (75/168). Analysis revealed that (113/136) Sus scrofa (pigs wild boars), while (30/33) waters. These findings highlight complex transmission dynamics The near-absence domestic pigs boars, despite its high proportion raises question about source infection. addition, near-exclusive detection suggests potential differences viral shedding, disease severity subtypes, or alternative host sources. This study emphasizes importance integrated One Health surveillance to track reservoirs.

Язык: Английский

Assessment of Hepatitis E Virus RNA Detection in Meat Samples: Optimization of Pre-analytical Conditions

Food and Environmental Virology, Год журнала: 2024, Номер 17(1)

Опубликована: Ноя. 19, 2024

Язык: Английский