Toxics, Год журнала: 2024, Номер 12(10), С. 759 - 759
Опубликована: Окт. 19, 2024
Antibiotics can affect the photosynthetic system of
Язык: Английский
Applied and Environmental Microbiology, Год журнала: 2025, Номер unknown
Опубликована: Янв. 8, 2025
ABSTRACT The Winam Gulf in the Kenyan region of Lake Victoria experiences prolific, year-round cyanobacterial harmful algal blooms (cyanoHABs) which pose threats to human, livestock, and ecosystem health. To our knowledge, there is limited molecular research on gulf’s cyanoHABs, thus, strategies employed for survival proliferation by toxigenic cyanobacteria this remain largely unexplored. Here, we used metagenomics analyze Gulf’s composition, function, biosynthetic potential. Dolichospermum was dominant bloom-forming cyanobacterium, co-occurring with Microcystis at most sites. Planktothrix were more abundant shallow turbid Metagenome-assembled genomes (MAGs) harbored nitrogen fixation genes, suggesting diazotrophy as a potential mechanism supporting nitrogen-limited gulf. Over 300 gene clusters (BGCs) putatively encoding synthesis toxins other secondary metabolites identified across gulf, even sites where no visible cyanoHAB events. Almost all BGCs had known product, indicating diverse novel repertoire capable synthesizing or potentially therapeutic metabolites. MAGs contained mcy genes hepatotoxic microcystins are concern drinking water safety. These findings illustrate spatial variation their available dominate different ecological niches. This study underscores need further use genomic techniques elucidate dynamics mitigate effects cyanoHABs associated environmental, economic
Язык: Английский
Процитировано
0
The Science of The Total Environment, Год журнала: 2025, Номер 963, С. 178443 - 178443
Опубликована: Янв. 15, 2025
Язык: Английский
Процитировано
0
Scientific Reports, Год журнала: 2025, Номер 15(1)
Опубликована: Янв. 24, 2025
Viruses that infect cyanobacteria are an integral part of aquatic food webs, influencing nutrient cycling and ecosystem health. However, the significance virus host range, replication efficiency, compatibility on cyanobacterial dynamics, growth, toxicity remains poorly understood. In this study, we examined effects cyanophage additions dynamics activity optimal, sub-optimal, non-permissive hosts in cultures Microcystis aeruginosa Raphidiopsis raciborskii. Our findings reveal cross-infectivity can substantially reduce proliferative success under conditions high-density sub-optimal which suggests phage dispersal limitation as a result shared infections, turn impairing their top-down control over community. Furthermore, found addition triggers strain-specific responses photosynthetic performance, population size toxin production, even among hosts. These non-lytic suggest indirect impacts co-existing cyanobacteria, increasing overall complexity variance many ecologically relevant traits. The high variability observed with limited subset cyanophage-cyanobacteria combinations not only highlights intricate role viral infections microbial ecosystems but also underscores significant challenges predicting composition, toxicity, blooms.
Язык: Английский
Процитировано
0
Environmental Research, Год журнала: 2025, Номер unknown, С. 121105 - 121105
Опубликована: Фев. 1, 2025
Язык: Английский
Процитировано
0
International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(4), С. 1554 - 1554
Опубликована: Фев. 12, 2025
Microcystis aeruginosa is an important species causing cyanobacterial blooms, which can be effectively infected and lysed by cyanophages. Several strategies have been developed M. to resist cyanophage infections, including the CRISPR-Cas systems. However, detailed information on systems in rare. In present study, of FACHB-524 were analyzed genome re-sequencing, showed that there are two type I (Cluster 1, I-B1; Cluster 2, I-D) three III-B 3/4/5) cyanobacteria. Further comparison revealed spacer sequences targeted several genes MaMV (M. myovirus) strains. One III 4) was then cloned expressed Escherichia coli BL21 (DE3). Protein purification mass spectrometry identification a Cmr-crRNA effector complex formed E. coli. Subsequently, T4 phage (T4) used infect coli, expressing with or without accessory proteins. The results exhibited anti-phage activity protein Csx1 enhanced immune complex. Collectively, our comprehensively demonstrate CRISPR encoded strain aeruginosa, for first time, one constructed into providing foundation further in-depth analysis
Язык: Английский
Процитировано
0
Hydrobiologia, Год журнала: 2025, Номер unknown
Опубликована: Фев. 24, 2025
Abstract Planktothrix rubescens is a filamentous, freshwater cyanobacterium that has gained outstanding attention due to its ecological significance, toxin production capabilities and potential risks it may pose human environmental health. The information related the species fragmented in hundreds of scientific articles; thus, our main goal was connect this knowledge, with hope one uncover can be applied widely subject. This comprehensive review delves into taxonomic classification, biogeography, drivers, interaction other species, management strategies P. rubescens. highlights community-forming role different environments, as well very complex biotic relationships, from viruses organisms at higher trophic levels .
Язык: Английский
Процитировано
0
Algal Research, Год журнала: 2025, Номер unknown, С. 103997 - 103997
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0
Journal of Phycology, Год журнала: 2025, Номер unknown
Опубликована: Март 22, 2025
Abstract Toxic cyanobacterial blooms have expanded and intensified on a global scale. Although microcystins are known as the most abundant cyanotoxins released during blooms, physiological role of these toxic secondary metabolites has not been fully resolved. Here, we show that microcystin production is important for Microcystis to maintain carbon metabolism under long‐term nitrogen starvation subsequent recovery. Compared in nonmicrocystin‐producing strains, could accumulate more reserves limitation, which survival cells stressful conditions. Transcriptomic analysis revealed genes involved synthesis were significantly up‐regulated at initial recovery phase, indicating their essential strengthening glycogen catabolism fueling Flow cytometry showed compared nontoxic microcystin‐producing exhibited higher rate after prolonged starvation, consistent with dominance species early stage blooms. The close genetic traits between strains suggest strategies observed here might be highly conserved. Our results imply establishes competitive advantage over provides insights into seasonal succession natural populations.
Язык: Английский
Процитировано
0
Ecological Modelling, Год журнала: 2025, Номер 504, С. 111094 - 111094
Опубликована: Апрель 4, 2025
Язык: Английский
Процитировано
0
Harmful Algae, Год журнала: 2025, Номер 146, С. 102871 - 102871
Опубликована: Апрель 28, 2025
Язык: Английский
Процитировано
0