Gut-mammary pathway: Breast milk microbiota as a mediator of maternal gut microbiota transfer to the infant gut

Journal of Functional Foods, Год журнала: 2024, Номер 124, С. 106620 - 106620

Опубликована: Дек. 13, 2024

Язык: Английский

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Milk matters: seeding gut ecosystems and shaping microbiota rivalries

Microbiome Research Reports, Год журнала: 2025, Номер 4(2)

Опубликована: Март 13, 2025

Maternal milk contains its own diverse microbiome, which has been hypothesized to colonize the infant gut during breastfeeding; however, dynamics of this process are not well understood, particularly among very-low-birth-weight (VLBW) infants. A recent study published in Cell Reports Medicine by Shama et al. identifies novel dose-dependent relationships between maternal microbiota and a cohort VLBW infants further explores potential impact feeding practices antibiotic use on these microbial colonization dynamics.

Язык: Английский

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Improving the quality of donor human milk to take advantage of more of the health benefits of mother's own milk composition

Current Opinion in Clinical Nutrition & Metabolic Care, Год журнала: 2025, Номер unknown

Опубликована: Фев. 18, 2025

Purpose of review Pasteurized donor human milk (PDHM) is the recommended supplement when there inadequate volume mother's own (MOM) for very low birth weight (<1500 g, VLBW) infants. Differences in composition these milks may impact growth, morbidities or long-term development The aim this to highlight current trends understanding compositional differences between MOM and PDHM, technological advances processing infant outcomes VLBW infants are fed milks. Recent findings Reported PDHM due several factors including how collected, sampled analysis, processed. Systematic reviews primary research studies demonstrate that reduces risk necrotizing enterocolitis but also associated with slower postnatal growth. Work ongoing determine if alternative approaches can improve thereby growth neurodevelopment reduce morbidity. Summary a key component feeding MOM. developments optimize source nutrition bioactive compounds while further limitations its use.

Язык: Английский

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Bioactive compounds in human milk

Current Opinion in Clinical Nutrition & Metabolic Care, Год журнала: 2025, Номер unknown

Опубликована: Фев. 12, 2025

Purpose of review: Human milk is the optimal food choice for infants. Reviewing latest advances in research about human compounds and their effect on health helps understand benefits breastfeeding improves knowledge key bioactive nutrients that can be used to improve feeding during infancy, with short long-time effects health. Recent findings: In last years, it has been described how such as oligosaccharides, hormones, lipids, cellular components microbes play an important role infants’ health, reducing risk infectious, metabolic autoimmune diseases. The mechanisms transmission from mother infant these are not always well described, but there several lines biological beneficial effects. Summary: These findings may help maternal interventions, modifiable factors able modulate composition. They development formulas enhance nutritional plans. Also, identification isolation describe new ways supplementation.

Язык: Английский

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Causal Effects of Birth Weight on Lung Function and the Mediating Role of Gut Microbiota: A Two-Step Mendelian Randomization Study

Опубликована: Янв. 1, 2025

Язык: Английский

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Sex-and stage-specific effect of prenatal exposure to organophosphate esters with children's physical growth patterns and adiposity rebound timing: Modification by breastfeeding

Journal of Hazardous Materials, Год журнала: 2025, Номер 493, С. 138309 - 138309

Опубликована: Апрель 17, 2025

Язык: Английский

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How human milk shapes the gut microbiota in preterm infants: potential for optimizing early-life microbial development

Microbiome Research Reports, Год журнала: 2024, Номер 4(1)

Опубликована: Дек. 23, 2024

Breast milk plays a crucial role in shaping the gut microbiota of preterm infants, with significant microbial sharing influenced by feeding practices and antibiotics, highlighting benefits direct breastfeeding for health.

Язык: Английский

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