Meta-analyses of the global impact of non-antibiotic feed additives on livestock performance and health

Journal of Advanced Research, Год журнала: 2025, Номер unknown

Опубликована: Март 1, 2025

The impact of non-antibiotic feed additives on livestock performance and health is contingent upon a multitude variables, including the animal species, dosage type additives, duration oral administration. However, there paucity knowledge regarding relationship between these factors animals. objective this study was to conduct global meta-analysis based pool empirical studies investigate effects dietary growth, production, blood metabolites, immunity, intestinal morphology, abundance gut microbiota in livestock. A meta-regression coupled with dose-effect analysis performed ascertain optimal feeding for body function. total 71 papers, estimating 1, 035 effect size across 9 species 7 types were recruited our meta-dataset. Overall assessment confirmed that diet can significantly improve production immune function species. Our findings indicated more pronounced herbivores than omnivores. dose-response results overall doses antimicrobial peptides, enzymes, oligosaccharides, organic acids, phytogenic, probiotics prebiotics 100 mg/kg, 30 200 50 10⁶ CFU/kg, 10 respectively. Oral administration 2-month period effectively improves health. This evidence-based approach provides foundation implementing customized strategies designed optimize performance, enhance immunity reduce costs. shows are promising alternatives antibiotics reducing use antibiotics. Furthermore, suggest lead recommendations practical strategies, providing producers sustainable cost-effective management.

Язык: Английский

Ergosterol originated from Auricularia auricula attenuates high fat diet-induced obesity and cognitive impairment in mice

Food & Function, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Ergosterol and Auricularia auricula attenuates high fat diet-induced obesity cognitive impairment in mice by regulating gut microbiota inhibiting the activation of microglia.

Язык: Английский