Aboral cell types of Clytia and coral larvae have shared features and link taurine to the regulation of settlement DOI Creative Commons
Julia Ramon-Mateu, Anna Ferraioli, Núria Teixidó

и другие.

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Ноя. 3, 2024

Abstract Planktonic larvae of many marine invertebrates settle on a suitable substrate and metamorphose into bottom-dwelling adults. Larval settlement is considerable interest both for ecologists evolutionary biologists, who have proposed that anterior sensory systems selection provided the basis animal brains. Nevertheless cellular molecular regulation larval settlement, including in Cnidaria (corals, jellyfish, sea anemones, hydroids) not well understood. We generated compared (aboral) transcriptomes single-cell RNA-seq datasets from planula three cnidarian species: hydrozoan jellyfish Clytia hemisphaerica, scleractinian corals Astroides calycularis Pocillopora acuta . Integrating these characterizing aboral cell types, we defined common architecture end, identified clade-specific specializations unique neural cells neurosecretory types with distinct signatures coral planulae. Among features were genes implicated taurine uptake catabolism expressed specialized types. In functional assays, exogenous inhibited These findings define detailed framework pole, implicate localized destruction defining competence.

Язык: Английский

Aboral cell types of Clytia and coral larvae have shared features and link taurine to the regulation of settlement DOI Creative Commons
Julia Ramon-Mateu, Anna Ferraioli, Núria Teixidó

и другие.

Science Advances, Год журнала: 2025, Номер 11(20)

Опубликована: Май 16, 2025

Larval settlement is of interest both for ecologists and evolutionary biologists, who have proposed that anterior sensory systems substrate selection provided the basis animal brains. Nevertheless, cellular molecular regulation settlement, including in Cnidaria (corals, jellyfish, sea anemones, hydroids), not well understood. We generated compared (aboral) transcriptomes single-cell RNA sequencing datasets from planula larvae three cnidarian species: jellyfish Clytia hemisphaerica corals Astroides calycularis Pocillopora acuta . Integrating these characterizing aboral cell types, we defined common features end identified clade-specific specializations types. Among shared were genes implicated taurine uptake catabolism expressed distinct specialized In functional assays using planulae, exogenous inhibited settlement. These findings define architecture pole implicate localized destruction regulating

Язык: Английский

Процитировано

0
Candidate stem cell isolation and transplantation in Hexacorallia DOI Creative Commons

Shani Talice,

Itamar Kozlovski,

Shany K. Barkan

и другие.

Cell Reports, Год журнала: 2024, Номер 43(11), С. 114944 - 114944

Опубликована: Ноя. 1, 2024

Stem cells are the foundation for cell therapy due to their ability self-renew, differentiate into other types, and persist throughout life of an organism. isolation transplantation have not yet been established in Hexacorallia, a cnidarian subclass containing stony corals sea anemones. Here, we demonstrate that candidate stem hexacorallian Nematostella vectensis can be transplanted adult animals. These exhibited hallmarks functional properties; they integrated recipients' tissues rescued them from lethal doses chemotherapy. Additionally, these proliferated survived serial transplantations. Notably, showed this cellular subpopulation enriched by sorting using species-non-specific markers similar subpopulations isolated hexacorallians, including corals. This research establishes basis studying biology on level Hexacorallia.

Язык: Английский

Процитировано

1
Aboral cell types of Clytia and coral larvae have shared features and link taurine to the regulation of settlement DOI Creative Commons
Julia Ramon-Mateu, Anna Ferraioli, Núria Teixidó

и другие.

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Ноя. 3, 2024

Abstract Planktonic larvae of many marine invertebrates settle on a suitable substrate and metamorphose into bottom-dwelling adults. Larval settlement is considerable interest both for ecologists evolutionary biologists, who have proposed that anterior sensory systems selection provided the basis animal brains. Nevertheless cellular molecular regulation larval settlement, including in Cnidaria (corals, jellyfish, sea anemones, hydroids) not well understood. We generated compared (aboral) transcriptomes single-cell RNA-seq datasets from planula three cnidarian species: hydrozoan jellyfish Clytia hemisphaerica, scleractinian corals Astroides calycularis Pocillopora acuta . Integrating these characterizing aboral cell types, we defined common architecture end, identified clade-specific specializations unique neural cells neurosecretory types with distinct signatures coral planulae. Among features were genes implicated taurine uptake catabolism expressed specialized types. In functional assays, exogenous inhibited These findings define detailed framework pole, implicate localized destruction defining competence.

Язык: Английский

Процитировано

0