Nature Chemical Biology,
Год журнала:
2023,
Номер
19(5), С. 651 - 662
Опубликована: Фев. 6, 2023
Abstract
Critical
to
a
sustainable
energy
future
are
microbial
platforms
that
can
process
aromatic
carbons
from
the
largely
untapped
reservoir
of
lignin
and
plastic
feedstocks.
Comamonas
species
present
promising
bacterial
candidates
for
such
because
they
use
range
natural
xenobiotic
compounds
often
possess
innate
genetic
constraints
avoid
competition
with
sugars.
However,
metabolic
reactions
these
underexplored,
regulatory
mechanisms
unknown.
Here
we
identify
multilevel
regulation
in
conversion
lignin-related
compounds,
4-hydroxybenzoate
vanillate,
plastics-related
compound,
terephthalate,
testosteroni
KF-1.
Transcription-level
controls
initial
catabolism
cleavage,
but
metabolite-level
thermodynamic
governs
fluxes
central
carbon
metabolism.
Quantitative
13
C
mapping
tricarboxylic
acid
cycle
cataplerotic
elucidates
key
routing
not
evident
enzyme
abundance
changes.
This
scheme
transcriptional
activation
coupled
fine-tuning
challenges
outcome
predictions
during
manipulations.
Polymers,
Год журнала:
2020,
Номер
12(4), С. 920 - 920
Опубликована: Апрель 15, 2020
The
success
of
oil-based
plastics
and
the
continued
growth
production
utilisation
can
be
attributed
to
their
cost,
durability,
strength
weight
ratio,
eight
contributions
ease
everyday
life.
However,
mainly
single
use,
durability
recalcitrant
nature
have
led
a
substantial
increase
as
fraction
municipal
solid
waste.
need
substitute
use
products
that
are
not
easy
collect
has
inspired
lot
research
towards
finding
sustainable
replacements
for
plastics.
In
addition,
specific
physicochemical,
biological,
degradation
properties
biodegradable
polymers
made
them
attractive
materials
biomedical
applications.
This
review
summarises
advances
in
drug
delivery
systems,
specifically
design
nanoparticles
based
on
polymers.
We
also
discuss
performed
area
biophotonics
challenges
opportunities
brought
by
application
tissue
engineering.
then
state-of-the-art
packaging
emphasise
smart
development.
Finally,
we
provide
an
overview
biodegradation
these
composites
managed
unmanaged
environments.
ACS Catalysis,
Год журнала:
2022,
Номер
12(6), С. 3382 - 3396
Опубликована: Фев. 28, 2022
Polyethylene
terephthalate
(PET)
is
the
most
widespread
synthetic
polyester,
having
been
utilized
in
textile
fibers
and
packaging
materials
for
beverages
food,
contributing
considerably
to
global
solid
waste
stream
environmental
plastic
pollution.
While
enzymatic
PET
recycling
upcycling
have
recently
emerged
as
viable
disposal
methods
a
circular
economy,
only
handful
of
benchmark
enzymes
thoroughly
described
subjected
protein
engineering
improved
properties
over
last
16
years.
By
analyzing
specific
material
reaction
mechanisms
context
interfacial
biocatalysis,
this
Perspective
identifies
several
limitations
current
degradation
approaches.
Unbalanced
enzyme-substrate
interactions,
limited
thermostability,
low
catalytic
efficiency
at
elevated
temperatures,
inhibition
caused
by
oligomeric
intermediates
still
hamper
industrial
applications
that
require
high
efficiency.
To
overcome
these
limitations,
successful
studies
using
innovative
experimental
computational
approaches
published
extensively
recent
years
thriving
research
field
are
summarized
discussed
detail
here.
The
acquired
knowledge
experience
will
be
applied
near
future
address
contributed
other
mass-produced
polymer
types
(e.g.,
polyamides
polyurethanes)
should
also
properly
disposed
biotechnological
Polymers,
Год журнала:
2021,
Номер
13(9), С. 1475 - 1475
Опубликована: Май 2, 2021
The
polyethylene
terephthalate
(PET)
application
has
many
challenges
and
potential
due
to
its
sustainability.
conventional
PET
degradation
was
developed
for
several
technologies
get
higher
yield
products
of
ethylene
glycol,
bis(2-hydroxyethyl
terephthalate)
terephthalic
acid.
chemical
recycling
is
reviewed,
such
as
pyrolysis,
hydrolysis,
methanolysis,
glycolysis,
ionic-liquid,
phase-transfer
catalysis
combination
glycolysis–hydrolysis,
glycolysis–methanolysis
methanolysis–hydrolysis.
Furthermore,
the
reaction
kinetics
conditions
were
investigated
both
theoretically
experimentally.
solve
environmental
problems
find
another
source
raw
material
petrochemical
energy.
Chemosphere,
Год журнала:
2023,
Номер
320, С. 138089 - 138089
Опубликована: Фев. 6, 2023
Human
society
has
become
increasingly
reliant
on
plastic
because
it
allows
for
convenient
and
sanitary
living.
However,
recycling
rates
are
currently
low,
which
means
that
the
majority
of
waste
ends
up
in
landfills
or
ocean.
Increasing
upcycling
is
a
critical
strategy
addressing
issues
caused
by
pollution,
but
there
several
technical
limitations
to
overcome.
This
article
reviews
advancements
polymer
technology
aim
improve
efficiency
waste.
In
food
packaging,
natural
polymers
with
excellent
gas
barrier
properties
self-cleaning
abilities
have
been
introduced
as
environmentally
friendly
alternatives
existing
materials
reduce
food-derived
contamination.
Upcycling
valorization
approaches
emerged
transform
into
high-value-added
products.
Recent
development
recyclable
high-performance
plastics
include
design
super
engineering
thermoplastics
chemical
bonds
thermosets
make
them
biodegradable.
Further
research
needed
develop
more
cost-effective
scalable
technologies
address
pollution
problem
through
sustainable
upcycling.
Earth
is
flooded
with
plastics
and
the
need
for
sustainable
recycling
strategies
polymers
has
become
increasingly
urgent.
Enzyme-based
hydrolysis
of
post-consumer
plastic
an
emerging
strategy
closed-loop
polyethylene
terephthalate
(PET).
The
polyester
hydrolase
PHL7,
isolated
from
a
compost
metagenome,
completely
hydrolyzes
amorphous
PET
films,
releasing
91
mg
terephthalic
acid
per
hour
enzyme.
Vertical
scanning
interferometry
shows
degradation
rates
film
6.8
μm
h
Microorganisms,
Год журнала:
2023,
Номер
11(7), С. 1661 - 1661
Опубликована: Июнь 26, 2023
Plastic
and
microplastic
pollution
has
caused
a
great
deal
of
ecological
problems
because
its
persistence
potential
adverse
effects
on
human
health.
The
degradation
plastics
through
biological
processes
is
significance
for
health,
therefore,
the
feasibility
plastic
by
microorganisms
attracted
lot
attention.
This
study
comprises
preliminary
discussion
biodegradation
mechanism
advantages
roles
different
bacterial
enzymes,
such
as
PET
hydrolase
PCL-cutinase,
in
polymers,
PCL,
respectively.
With
particular
focus
their
modes
action
enzymatic
mechanisms,
this
review
sums
up
studies
microplastics
related
to
mechanisms
influencing
factors,
along
with
enzymes
enhancing
synthetic
process.
In
addition,
also
affected
additives
plasticizers.
Plasticizers
composition
can
cause
harmful
impacts.
To
further
improve
efficiency
various
pretreatments
biodegradation,
which
significant
reduction
toxic
pollution,
were
preliminarily
discussed
here.
existing
research
data
show
large
number
involved
though
specific
have
not
been
thoroughly
explored
yet.
Therefore,
there
employing
strains
efficient
health
safety.
In
the
movement
to
decarbonize
our
economy
and
move
away
from
fossil
fuels
we
will
need
harness
waste
products
of
activities,
such
as
lignocellulose,
methane,
carbon
dioxide.
Our
wastes
be
integrated
into
a
circular
where
used
are
recycled
manufacturing
cycle.
Key
this
recycling
plastics
at
resin
monomer
levels.
Biotechnology
is
well
suited
future
chemical
industry
that
must
adapt
widely
distributed
diverse
biological
feedstocks.
increasing
mastery
biotechnology
allowing
us
develop
enzymes
organisms
can
synthesize
widening
selection
desirable
bulk
chemicals,
including
plastics,
commercially
viable
productivities.
Integration
bioreactors
with
electrochemical
systems
permit
new
production
opportunities
enhanced
productivities
advantage
using
low-carbon
electricity
renewable
sustainable
sources.
