Covalent Organic Frameworks: Recent Progress in Biomedical Applications

ACS Nano, Год журнала: 2023, Номер 17(3), С. 1879 - 1905

Опубликована: Янв. 30, 2023

Covalent organic frameworks (COFs) are a type of crystalline porous material with specific features and interesting structures, including porosity, large surface area, biocompatibility. These enable COFs to be considered as excellent candidates for applications in various fields. Recently, have been widely demonstrated promising materials biomedical because their physicochemical properties ultrathin structures. In this review, we cover the recent progress COF photodynamic therapy, gene delivery, photothermal drug bioimaging, biosensing, combined therapies. Moreover, critical challenges further perspectives regards future biology-facing also discussed.

Язык: Английский

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Covalent Organic Framework Based Lithium–Sulfur Batteries: Materials, Interfaces, and Solid‐State Electrolytes

Advanced Energy Materials, Год журнала: 2023, Номер 13(10)

Опубликована: Янв. 20, 2023

Abstract Lithium–sulfur batteries are recognized as one of the most promising next‐generation energy‐storage technologies owing to their high energy density and low cost. Nevertheless, shuttle effect polysulfide intermediates formation lithium dendrites principal reasons that restrict practical adoption current Li–S batteries. Adjustable frameworks, structural variety, functional adaptability covalent organic frameworks (COFs) have potential overcome issues associated with battery technology. Herein, a summary is presented emerging COF materials in addressing challenging problems terms sulfur hosts, modified separators, artificial solid electrolyte interphase layers, solid‐state electrolytes. This comprehensive overview focuses on design chemistry COFs used upgrade Furthermore, existing difficulties, prospective remedies, research directions for discussed, laying groundwork future advancements this class fascinating materials.

Язык: Английский

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Photocatalytic Antimicrobials: Principles, Design Strategies, and Applications

Chemical Reviews, Год журнала: 2023, Номер 123(22), С. 12371 - 12430

Опубликована: Авг. 24, 2023

Nowadays, the increasing emergence of antibiotic-resistant pathogenic microorganisms requires search for alternative methods that do not cause drug resistance. Phototherapy strategies (PTs) based on photoresponsive materials have become a new trend in inactivation due to their spatiotemporal controllability and negligible side effects. Among those phototherapy strategies, photocatalytic antimicrobial therapy (PCAT) has emerged as an effective promising strategy recent years. In process treatment, are excited by different wavelengths lights produce reactive oxygen species (ROS) or other toxic killing various microbes, such bacteria, viruses, fungi, parasites, algae. Therefore, this review timely summarizes latest progress PCAT field, with emphasis development antimicrobials (PCAMs), underlying mechanisms, design multiple practical applications local infections therapy, personal protective equipment, water purification, coatings, wound dressings, food safety, antibacterial textiles, air purification. Meanwhile, we also present challenges perspectives widespread implementation therapeutics. We hope result review, will flourish weapon against antibiotic

Язык: Английский

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In Situ Synthesis of Chemically Bonded 2D/2D Covalent Organic Frameworks/O‐Vacancy WO₃ Z‐Scheme Heterostructure for Photocatalytic Overall Water Splitting

Advanced Materials, Год журнала: 2023, Номер 35(33)

Опубликована: Июнь 15, 2023

Abstract Covalent organic frameworks (COFs) have shown great promise for photocatalytic hydrogen evolution via water splitting. However, the four‐electron oxidation of remains elusive toward oxygen evolution. Enabling this pathway is critical to improve yield and maximize atom utilization efficiency. A Z‐scheme heterojunction proposed overcoming fundamental issues in COF‐based overall splitting (OWS), such as inefficient light absorption, charge recombination, poor ability. It that construction a novel 2D/2D through situ growth COFs on O‐vacancy WO 3 nanosheets (Ov‐WO ) WOC chemical bond can remarkably promote OWS. Benefiting from synergistic effect between enhanced built‐in electric field by interfacial bond, strong ability Ov‐WO 3, ultrathin structure TSCOF, both separation efficiency photogenerated electron–hole pairs be significantly enhanced. An impressive half‐rection rate 593 mmol h −1 g 146 (hydrogen) 68 (oxygen) µmol are achieved COF‐WO (TSCOFW) composite. This with two‐step excitation precisely cascaded charge‐transfer makes it responsible efficient solar‐driven OWS without sacrificial agent.

Язык: Английский

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Post-synthetic modification of covalent organic frameworks for CO2 electroreduction

Nature Communications, Год журнала: 2023, Номер 14(1)

Опубликована: Июнь 26, 2023

To achieve high-efficiency catalysts for CO2 reduction reaction, various catalytic metal centres and linker molecules have been assembled into covalent organic frameworks. The amine-linkages enhance the binding ability of molecules, ionic frameworks enable to improve electronic conductivity charge transfer along However, directly synthesis with is hardly achieved due electrostatic repulsion predicament strength linkage. Herein, we demonstrate reaction by modulating linkers linkages template framework build correlation between performance structures Through double modifications, states are well tuned, resulting in controllable activity selectivity reaction. Notably, dual-functional achieves high a maximum CO Faradaic efficiency 97.32% turnover frequencies value 9922.68 h-1, which higher than those base single-modified Moreover, theoretical calculations further reveal that attributed easier formation immediate *CO from COOH*. This study provides insights developing

Язык: Английский

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Superhydrophilic 2D Covalent Organic Frameworks as Broadband Absorbers for Efficient Solar Steam Generation

Angewandte Chemie International Edition, Год журнала: 2022, Номер 61(19)

Опубликована: Март 2, 2022

The intrinsic hydrophobicity and limited light absorption especially in the near-infrared (NIR) region of porous organic polymers are two bottlenecks impeding their applications solar steam generation (SSG). Herein, we develop a 1,4,5,8-tetrakis(phenylamino)anthracene-9,10-dione (TPAD)-based covalent framework (COF) (TPAD-COF) featuring both superhydrophilicity broad covering from entire UV/Vis to NIR regions for SSG. TPAD-COF serving as highly efficient photothermal conversion material without any additives displays an excellent water evaporation 1.42 kg m-2 h-1 achieves high energy efficiency 94 % under 1 sun irradiation. Further extension range TPAD-based COF is realized through post-synthetic modification by chelating BF2 moieties. Systematic control experiments analysis confirm that hydrophilicity materials plays more dominant role current COFs

Язык: Английский

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Nickel Glyoximate Based Metal–Covalent Organic Frameworks for Efficient Photocatalytic Hydrogen Evolution

Angewandte Chemie International Edition, Год журнала: 2022, Номер 61(30)

Опубликована: Май 13, 2022

Abstract Metal–covalent organic frameworks (MCOFs) have been recently received wide attention owing to the homogeneous distribution of active metal centers that are beneficial for enhancing application potentials. However, complex based functional building blocks MCOFs synthesis limited. Herein, two new (Ni‐Py‐COF and Ni‐Bn‐COF) were constructed via a novel nickel glyoximate block. Splendid photocatalytic activity on hydrogen evolution from water great long‐term recyclability achieved using these as photocatalysts. Excitingly, even without addition Pt co‐catalyst, rates (HER) Ni‐Py‐COF reached up 626 μmol g −1 h , which is better than many porous polymers. This work not only expands type units MCOFs, but also provides meaningful insights developing stable, efficient earth‐abundant photocatalysts toward H 2 generation.

Язык: Английский

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Enaminone‐Linked Covalent Organic Frameworks for Boosting Photocatalytic Hydrogen Production

Angewandte Chemie International Edition, Год журнала: 2023, Номер 62(31)

Опубликована: Май 31, 2023

Covalent organic frameworks (COFs), possessing pre-designable structures and tailorable functionalities, are promising candidates for photocatalysis. Nevertheless, the most studied imine-linked COFs (Im-COFs) usually suffer from unsatisfactory stability photocatalytic performance. To meet this challenge, a series of highly stable enaminone-linked (En-COFs) have been synthesized afford much improved visible-light-driven hydrogen production activities, ranging 44 to 1078 times that isoreticular Im-COFs, with only difference being linkages (enaminone vs. imine) in their structures. The enhanced light-harvesting ability, facilitated exciton dissociation chemical account superior activity. Furthermore, quinoline-linked (Qu-COFs) further obtained via post-modification Im-COFs. Compared activities Qu-COFs significantly after modification, but still below those corresponding En-COFs (3-107 times). facile synthesis, excellent activity, high demonstrate platform

Язык: Английский

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Isomeric Oligo(Phenylenevinylene)‐Based Covalent Organic Frameworks with Different Orientation of Imine Bonds and Distinct Photocatalytic Activities

Angewandte Chemie International Edition, Год журнала: 2022, Номер 62(5)

Опубликована: Дек. 1, 2022

Imine-linked covalent organic frameworks (COFs) have been extensively studied in photocatalysis because of their easy synthesis and excellent crystallinity. The effect imine-bond orientation on the photocatalytic properties COFs, however, is still rarely studied. Herein, we report two novel COFs with different orientations imine bonds using oligo(phenylenevinylene) moieties. showed similar structures but great differences photoelectric properties. COF-932 demonstrated a superior hydrogen evolution performance compared to COF-923 when triethanolamine was used as sacrificial agent. Interestingly, use ascorbic acid led protonation further altering direction electron transfer. performances were increased 23.4 0.73 mmol g-1 h-1 for protonated COF-932, respectively. This study provides clear strategy design imine-linked COF-based photocatalysts advances development COFs.

Язык: Английский

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Highly Crystalline Polyimide Covalent Organic Framework as Dual-Active-Center Cathode for High-Performance Lithium-Ion Batteries

Journal of the American Chemical Society, Год журнала: 2022, Номер 144(51), С. 23534 - 23542

Опубликована: Дек. 13, 2022

Polyimide covalent organic framework (PI-COF) materials that can realize intrinsic redox reactions by changing the charge state of their electroactive sites are considered as emerging electrode for rechargeable devices. However, highly crystalline PI-COFs with hierarchical porosity less reported due to rapid reaction between monomers and poor reversibility polyimidization reaction. Here, we developed a water-assistant synthetic strategy adjust rate polyimidization, PI-COF (COFTPDA-PMDA) kgm topology consisting dual active centers N,N,N′,N′-tetrakis(4-aminophenyl)-1,4-benzenediamine (TPDA) pyromellitic dianhydride (PMDA) ligands was successfully synthesized high crystallinity porosity. The COFTPDA-PMDA possesses micro-/mesoporous channels largest surface area (2669 m2/g) in PI-COFs, which promote Li+ ions bulky bis(trifluoromethanesulfonyl)imide (TFSI–) electrolyte sufficiently interact on COF skeleton increase specific capacity cathode materials. As material lithium-ion batteries, COFTPDA-PMDA@50%CNT integrated center carbon nanotubes via π–π interactions gave initial 233 mAh/g (0.5 A/g) maintains at 80 even current density 5.0 A/g after 1800 cycles.

Язык: Английский

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