Fusion of Four Aromatic Rings via an Atom-Mutual-Embedding Strategy to Form a Tetrahexacyclic System DOI
Fei‐Hu Cui, Le‐Han Gao,

Kaidong Ruan

и другие.

Journal of the American Chemical Society, Год журнала: 2025, Номер unknown

Опубликована: Апрель 14, 2025

Skeletal manipulation of aromatic compounds has emerged as a potent tool in synthetic chemistry, but simultaneous multiring remains largely unexplored due to the inherent complexities ring and site selectivity. Herein, we report an unprecedented skeletal that fuses four 5-membered rings, comprising two organic metal-containing systems, into novel metal-bridged 6/6/6/6-membered scaffold. The sequential fusion is accomplished through atom-mutual-embedding strategy; this strategy entails stepwise insertion nitrogen atoms separate metal-carbon bonds simultaneously integrates metal atom bridge across isoxazole moieties. presence central crucial for ensuring precise substrate alignment enhancing both specificity. resulting tetrahexacyclic products exhibit remarkable stability superior near-infrared (NIR) functional properties, surpassing those precursor compounds. This work not only establishes conceptual foundation designing versatile molecules amenable intricate editing also contributes rational performance-targeted molecular architectures.

Язык: Английский

Fusion of Four Aromatic Rings via an Atom-Mutual-Embedding Strategy to Form a Tetrahexacyclic System DOI
Fei‐Hu Cui, Le‐Han Gao,

Kaidong Ruan

и другие.

Journal of the American Chemical Society, Год журнала: 2025, Номер unknown

Опубликована: Апрель 14, 2025

Skeletal manipulation of aromatic compounds has emerged as a potent tool in synthetic chemistry, but simultaneous multiring remains largely unexplored due to the inherent complexities ring and site selectivity. Herein, we report an unprecedented skeletal that fuses four 5-membered rings, comprising two organic metal-containing systems, into novel metal-bridged 6/6/6/6-membered scaffold. The sequential fusion is accomplished through atom-mutual-embedding strategy; this strategy entails stepwise insertion nitrogen atoms separate metal-carbon bonds simultaneously integrates metal atom bridge across isoxazole moieties. presence central crucial for ensuring precise substrate alignment enhancing both specificity. resulting tetrahexacyclic products exhibit remarkable stability superior near-infrared (NIR) functional properties, surpassing those precursor compounds. This work not only establishes conceptual foundation designing versatile molecules amenable intricate editing also contributes rational performance-targeted molecular architectures.

Язык: Английский

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