Analytical Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 19, 2024
Methylglyoxal
is
considered
a
key
indicator
in
evaluating
wine
flavor
and
quality,
as
well
an
important
marker
for
diabetic
pathological
syndromes.
Rapid
accurate
quantitative
detection
of
methylglyoxal
essential
scenarios
production
standards
human
health
monitoring.
Herein,
we
report
visual
method
detecting
via
NIR-excitable
reversible
ratiometric
fluorescent
hydrogel
sensor,
where
NIR-excited
upconversion
nanoparticles
serve
energy
donors
eosin
B
acts
the
acceptor,
together
forming
integrated
nanophotonic
probe
that
ensures
accuracy
without
being
affected
by
various
background
fluorescence
interference
different
scenarios.
The
optical
combined
with
3D
network
to
design
sensing
patch
can
be
easily
regenerated
through
simple
treatment,
exhibiting
distinct
color
response.
Upon
addition
methylglyoxal,
G/R
value
changes,
enabling
real-time
methylglyoxal.
Additionally,
smartphone
create
portable
platform
convenient
have
limits
low
59
75.4
nM,
respectively.
designed
here
provides
effective
strategy
standardizing
process
monitoring
patient
health.
Analytical Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 21, 2025
Organic
photoelectrochemical
transistor
(OPECT)
has
undergone
significant
advancements,
enabling
an
effective
synergy
between
organic
electronics
and
photoelectrochemistry,
contributing
to
opto-logic
gates,
neuromorphic
emulation,
biological
detection.
However,
feasible
OPECT
operation
is
still
quite
limited
the
associated
technology
evolving.
This
study
introduces
a
self-enhancement
facilitated
by
triple-functional
stimuli-responsive
molecules
(SROM).
The
representative
SROM
sensitizes
photogate
selectively
recognize
chosen
target,
where
reaction
product
serves
reengineer
band
alignment,
resulting
in
self-enhanced
modulation.
We
further
leverage
this
effect
implement
highly
selective
detection
of
sulfite.
findings
work
bridge
gap
SROM,
demonstrating
potential
unique
implementation.
Hydrogels
have
emerged
as
promising
sensors
for
detecting
heavy
metal
ions
in
fluids
and
been
extensively
developed.
However,
monitoring
of
multiple
target
analytes
Chinese
herbs
remains
challenging
due
to
subtle
chemical
signals
the
complex
composition
extracted
solutions.
To
address
these
challenges,
we
developed
a
hydrogel
optofluidic
sensor
amplify
analyte
through
strong
light-matter
interactions
within
hydrogel.
This
sensing
platform
integrates
film
encapsulated
whispering-gallery-mode
(WGM)
microcavity
detection
ions,
such
Pb2+
Hg2+.
The
3D
cross-linked
hydrophilic
polymer
network
facilitates
ion
penetration
from
solutions,
inducing
distinct
WGM
resonance
shifts.
red
shift
spectral
wavelength
serves
parameter
quantify
content
ions.
By
modification
with
aptamers,
achieve
high
sensitivity
selectivity.
Finally,
platform's
performance
was
demonstrated
using
varying
concentrations,
highlighting
its
practical
applicability
real-world
scenarios.
proposed
exhibit
method
development
functional
healthcare
applications.
Advanced Materials,
Год журнала:
2024,
Номер
36(35)
Опубликована: Июнь 27, 2024
Due
to
the
presence
of
unpaired
electron
orbitals
in
most
lanthanide
ions,
lanthanide-doped
nanoparticles
(LnNPs)
exhibit
paramagnetism.
However,
as
biosensing
applications,
magnetism
LnNPs
is
so
weak
that
can
hardly
be
employed
target
separation.
Herein,
it
discovered
highly
associated
with
their
concentration
a
confined
space,
enabling
aggregation-augmented
make
them
susceptive
conventional
magnet.
Accordingly,
magnetic
levitation
(Maglev)
sensing
system
designed,
which
exosomes
specifically
introduce
paramagnetic
microbeads'
surface,
allowing
and
further
leverage
height
Maglev
device
indicate
exosomes'
content.
It
demonstrated
this
precisely
distinguish
healthy
people's
blood
samples
from
those
breast
cancer
patients.
This
first
work
report
hold
great
promise
separation-based
biological
sample
sorting,
LnNP-permitted
proven
promising
for
establishing
new
generation
devices.
Analytical Chemistry,
Год журнала:
2024,
Номер
96(47), С. 18736 - 18744
Опубликована: Ноя. 13, 2024
Enzymatic
cascade
reactions
with
high
activity
and
specificity
in
living
cells
always
benefit
from
multicompartmentalized
organelles
that
provide
separately
confined
spaces
for
enzymes,
avoiding
their
mutual
interference
to
ensure
the
high-efficiency
operation
of
necessary
vital
movements.
Inspired
by
this,
we
designed
a
3D
spherical
microreactor
(Au@H-APF@Pt)
biomimetic
catalysis
glucose
detection.
First,
ultrasmall
gold
nanoparticles
were
immobilized
situ
on
internal
cavities
hollow
3-aminophenol
formaldehyde
resin
(H-APF)
nanospheres,
along
oxidase
activity.
Then,
platinum
(PtNPs)
peroxide-like
reduced
surrounding
outer
layer
H-APF
nanospheres.
Similar
cell
structure,
different
metal
sites
this
bifunctional
operated
independently,
bringing
higher
catalytic
selectivity
thus
being
synergistically
capable
reaction
catalyze
substrate
This
cell-mimicking
was
successfully
applied
colorimetric
detection,
showing
1.9-fold
enhancement
compared
direct
mixing
(Au/Pt).
The
observed
low
attributed
extended
time
transferring
hydrogen
peroxide
(H
