Engineering Two-Dimensional-Copper Phenolic Nanosheet from CuO Nanosphere for Enhanced Peroxidase Activity in Smartphone-Based Thiophanate-Methyl Detection via Analyte-Inhibition Mechanism

Langmuir, Год журнала: 2025, Номер unknown

Опубликована: Март 10, 2025

Optical sensors based on nanozymes have shown great promise for the rapid and sensitive detection of pesticide residues in environmental food samples. However, their applicability is often limited by a lack selectivity due to nonspecific enzyme inhibition. Therefore, we developed colorimetric sensing platform specifically tailored detect agricultural fungicide thiophanate-methyl (TpM), leveraging its unique inhibitory effect nanozyme activity. The symmetric ethylenediamine- bisthiourea-like groups TpM exhibit strong affinity metal sites, leading reduction catalytic performance. Thus, designed novel copper oxide nanosphere (CuO)-derived 2D phenolic nanosheet (2D-CuPNS) with enhanced peroxidase-like This facilitates oxidation TMB through OH radical generation via Fenton-like reaction involving Cu2+/Cu+ -C═C- bonds surface. Notably, activity 2D-CuPNS was selectively significantly inhibited specific interaction while remaining unaffected other pesticides. exhibited affinities H2O2, Km values 0.07 2.0 mM, respectively. As result, proposed sensor demonstrated high specificity detection, linear range 0.5-15 μM low limit 0.09 μM. A smartphone-assisted method also utilizing RGB from chromogenic reaction. Furthermore, immobilization substrate onto standard filter paper, ready-to-use paper-based were created. study introduces inhibition approach selective samples, providing versatile practical solution.

Язык: Английский

Three-channel sensor array based on switchable nanozymatic reactions of a Novel trimetallic nanozyme for anti-interference identification of tea adulteration

Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 162447 - 162447

Опубликована: Апрель 1, 2025

Язык: Английский