Magnetic UiO-66-NH₂ Core–Shell Nanohybrid as a Promising Carrier for Quercetin Targeted Delivery toward Human Breast Cancer Cells

ACS Omega, Год журнала: 2023, Номер 8(44), С. 41321 - 41338

Опубликована: Окт. 24, 2023

In this study, a magnetic core–shell metal–organic framework (MOF) nanocomposite, Fe3O4-COOH@UiO-66-NH2, was synthesized for tumor-targeting drug delivery by incorporating carboxylate groups as functional onto ferrite nanoparticle surfaces, followed fabrication of the UiO-66-NH2 shell using facile self-assembly approach. The anticancer quercetin (QU) loaded into nanoparticles. nanoparticles were comprehensively evaluated through multiple techniques, including FT-IR, PXRD, FE-SEM, TEM, EDX, BET, UV–vis, ZP, and VSM. Drug release investigations conducted to investigate behavior QU from nanocomposite at two different pH values (7.4 5.4). results revealed that QU@Fe3O4-COOH@UiO-66-NH2 exhibited high loading capacity 43.1% pH-dependent behavior, maintaining sustained characteristics over prolonged duration 11 days. Furthermore, cytotoxicity assays human breast cancer cell line MDA-MB-231 normal HEK-293 performed evaluate cytotoxic effects QU, UiO-66-NH2, Fe3O4-COOH, QU@Fe3O4-COOH@UiO-66-NH2. Treatment with substantially reduced viability in cancerous cells. Cellular uptake death mechanisms further investigated, demonstrating internalization cells induction apoptosis pathway. These findings highlight considerable potential Fe3O4-COOH@UiO-66-NH2 targeted nanocarrier drugs.

Язык: Английский

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Selective separation of CO2/CH4 gases by metal-organic framework-based composites

Coordination Chemistry Reviews, Год журнала: 2024, Номер 520, С. 216126 - 216126

Опубликована: Авг. 14, 2024

Язык: Английский

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Gas adsorption and fluorescence studies of Cd2+ and Zn2+ metal organic frameworks based on the same fluorinated ligand

Journal of Molecular Structure, Год журнала: 2024, Номер 1312, С. 138575 - 138575

Опубликована: Май 14, 2024

Язык: Английский

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Nanoporous Metal–Organic Framework Based on Furan-2,5-Dicarboxylic Acid with High Potential in Selective Adsorption and Separation of Gas Mixtures

Crystal Growth & Design, Год журнала: 2024, Номер 24(10), С. 4220 - 4231

Опубликована: Май 6, 2024

Today, due to the momentary release of carbon dioxide and increasing global heat, solutions that prevent this greenhouse gas into atmosphere are very important. In work, a nanoporous sorbent with 3D framework chemical formula [Ca1.5(FDC)1.5(DMF)] (MUT-13) (FDC2–= furan-2,5-dicarboxylate, DMF= N,N-dimethylformamide) was prepared in different synthetic routes. Single crystal MUT-13 identified by X-ray crystallographic analysis other physicochemical analyses. Then, help GCMC, performance simulated adsorption various gases (CO2, H2, C2H2, CH4, N2) under temperature pressure conditions. Also, potential separating from binary mixtures (CO2/CH4, CO2/N2, CO2/H2 CO2/C2H2) investigated. The results indicated sorption structure has high capacity adsorb (6.2 mmol.g–1) acetylene (5.5 molecules environmental It also shows separation greater than 5000 2000 for mixture CO2:H2 at low pressures, respectively. This good adsorbing compared MOF-based adsorbents can be related surface its pores decorated heteroatom ligand presence unsaturated metal centers structure.

Язык: Английский

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Ag@MUT-16 nanocomposite as a Fenton-like and plasmonic photocatalyst for degradation of Quinoline Yellow under visible light

Dalton Transactions, Год журнала: 2024, Номер 53(26), С. 11094 - 11111

Опубликована: Янв. 1, 2024

A new cobalt-based metal-organic framework with the chemical formula of [Co

Язык: Английский

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The Effect of Layering Order of ZIF-8@PCL/PLA Composites in Electrospinning and Electrosprraying Process on Antibacterial Wound Healing

Materials Chemistry and Physics, Год журнала: 2024, Номер 328, С. 129878 - 129878

Опубликована: Авг. 26, 2024

Язык: Английский

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Porosity control in pillar-layered MOF architectures: hydrogen bonding in amino-functionalized 2-D layers

CrystEngComm, Год журнала: 2024, Номер 26(34), С. 4708 - 4719

Опубликована: Янв. 1, 2024

The effect of porosity control in three new pillar-layered MOF structures by hydrogen bonding amino-functionalized linker on the selective gas adsorption.

Язык: Английский

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rGO/MUT-15 nanocomposite as a Fenton-like photocatalyst for the degradation of Acid Yellow 73 under visible light

Dalton Transactions, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

A new Mn-based MOF (MUT-15) with the formula [Mn 2 (DClTPA) (DMF) 3 ] was prepared using a solvothermal method. rGO/MUT-15 formed via one-pot route. The Fenton-like effect of Mn 2+ ions in MUT-15 used to degrade Acid Yellow 73.

Язык: Английский

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Efficient Gas Adsorption in MUT-11: Insights from Theoretical Calculations and GCMC Simulations

Crystal Growth & Design, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 27, 2024

Язык: Английский

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