Solubility Determination and Data Correlation of 4-Methoxybenzoic Acid in 14 Pure Solvents at Temperatures from 283.15 to 328.15 K
Journal of Chemical & Engineering Data,
Год журнала:
2024,
Номер
69(3), С. 1368 - 1379
Опубликована: Янв. 5, 2024
The
solubility
of
4-methoxybenzoic
acid
in
14
pure
solvents
(1-butanol,
isobutanol,
2-butanol,
1-pentanol,
ethylene
glycol,
ethyl
formate,
1-propyl
acetate,
isopropyl
n-butyl
acetone,
2-butanone,
cyclohexanone,
toluene,
and
tetrahydrofuran)
was
determined
through
a
gravimetric
method
at
temperatures
from
283.15
to
328.15
K.
experimental
showed
an
increasing
trend
with
temperature.
Four
thermodynamic
models,
including
Modified
Apelblat
model,
NRTL
Van't
Hoff
λh
were
selected
correlate
the
further
fit
data.
results
revealed
that
calculated
four
models
good
correlation
data,
equation
providing
best
fitting
accuracy.
Furthermore,
mixing
properties
derived
indicated
processes
are
spontaneous
entropy
driven.
In
addition,
solvent
investigated
elucidate
solid–liquid
equilibrium
behavior
solvents.
Язык: Английский
Deep-learning based in-situ micrograph analysis of high-density crystallization slurry using image and data enhancement strategy
Powder Technology,
Год журнала:
2024,
Номер
437, С. 119582 - 119582
Опубликована: Март 1, 2024
Язык: Английский
Solubility Determination and Thermodynamic Modeling of Phenprobamate in 12 Pure Solvents from 283.15 to 323.15 K
Journal of Chemical & Engineering Data,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 13, 2025
Язык: Английский
Solid-Liquid Equilibrium Behavior and Data Correlation of Furosemide in 12 Pure Solvents from 283.15 to 323.15 K
Journal of Chemical & Engineering Data,
Год журнала:
2024,
Номер
69(6), С. 2380 - 2390
Опубликована: Май 29, 2024
In
this
paper,
the
solubility
of
furosemide
in
12
monosolvents
including
methanol,
ethanol,
n-propanol,
isopropanol,
n-butanol,
sec-butanol,
1-pentanol,
acetone,
2-butanone,
methyl
acetate,
ethyl
and
water
was
measured
by
using
a
static
gravimetric
method
within
temperature
range
283.15
to
323.15
K
under
atmospheric
pressure.
The
magnitudes
show
an
increasing
tendency
with
increase
all
solvents.
Within
entire
range,
is
lowest
(0.0053
×
10–3
at
K)
highest
1-pentanol
(72.736
K).
rough
subsequence
>
methanol
n-propanol
ethanol
isopropanol
sec-butanol
n-butanol
alcoholic
solvents
acetone
>2-butanone
acetate
nonalcohol
behavior
result
combined
effects
solvent
polarity,
solvent–solvent
intermolecular
interactions
(characterized
cohesive
energy
density),
summation
hydrogen
bond
acceptor
propensities.
Moreover,
experimental
data
were
fitted
models
Apelblat
Yaws.
results
indicate
that
two
could
both
correlate
values
satisfactorily,
Yaws
model
more
appropriate
fit
compared
model.
Язык: Английский
New Findings on the Crystal Polymorphism of Imepitoin
Molecules,
Год журнала:
2024,
Номер
29(8), С. 1724 - 1724
Опубликована: Апрель 11, 2024
Scientific
and
industrial
reasons
dictate
the
study
of
solid
state
imepitoin,
a
highly
safe
tolerable
anticonvulsant
drug
used
in
therapy
epileptic
dogs
that
was
approved
Europe
Union
2013.
Our
investigations
allowed
us
to
discover
existence
new
polymorph
which
finds
itself
monotropic
relationship
with
crystalline
form
(polymorph
I)
already
known
present
on
market.
This
II),
obtained
by
crystallization
from
xylene,
remains
metastable
under
ambient
conditions
for
at
least
1
year.
Both
forms
were
characterized
thermal
(DSC
TGA),
spectroscopic
(FT-IR
Raman),
microscopic
(SEM
HSM),
diffractometric
techniques.
The
thermodynamic
between
two
polymorphs
(monotropic)
is
such
it
not
possible
melting
II,
even
adopting
appropriate
experimental
strategies.
measurements
highlighted
peak
imepitoin
actually
also
includes
an
onset
melt
decomposition.
ab
initio
structure
solution,
synchrotron
X-ray
powder
diffraction
data
collected
room
temperature,
determine
crystal
(II).
It
crystallizes
monoclinic
structure,
P2
Язык: Английский