Advanced Healthcare Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 16, 2025
Abstract
NIR‐II
fluorescence
imaging
has
shown
broad
application
prospects
in
life
science
because
of
its
deeper
tissue
penetration
and
higher
spatiotemporal
resolution.
Developing
fluorophores
with
special
spectroscopic
properties
analytical
functions
become
a
cutting‐edge
but
challenging
topic
this
field.
Herein,
series
azulene‐based
(called
cyazulenes)
adjustable
cycloalkenes
for
applications
is
reported.
Cyazulenes
(CA965,
CA985,
CA1025)
are
constructed
via
the
convenient
coupling
azulene
derivatives.
They
exhibit
different
H‐aggregation
J‐aggregation.
Particularly
noteworthy
that
CA985
can
form
significant
J‐aggregates
strong
sharp
emission
biological
media,
be
used
vivo
blood
vessels
fine
structures
collecting
lymphatics
mice.
Moreover,
displays
passive
bone‐targeted
capacity,
thereby
enabling
bone
imaging.
This
study
demonstrates
chemical
impact
varying
on
aggregate
formation
spectral
cyazulenes,
which
will
advance
fluorophores.
Journal of the American Chemical Society,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 27, 2025
The
advent
of
autonomous
nanomotors
presents
exciting
opportunities
for
nanodrug
delivery.
However,
significant
potential
remains
enhancing
the
asymmetry
and
advancing
development
second
near-infrared
(NIR-II)
light-propelled
capable
operating
within
deep
tissues.
Herein,
we
developed
a
dual-ligand
assisted
anisotropic
assembly
strategy
that
enables
precise
regulation
interfacial
energy
between
selenium
(Se)
nanoparticle
periodic
mesoporous
organosilica
(PMO).
This
facilitates
controllable
growth
PMO
on
Se
nanoparticle,
leading
to
formation
Se&PMO
Janus
nanohybrids.
exposure
ratio
subunit
nanohybrids
can
be
finely
tuned
from
0%
75%.
Leveraging
transformability
subunit,
variety
functional
MxSe&PMO
nanocomposites
(MxSe
denotes
metal
selenide)
were
further
derived.
As
proof
concept,
CuSe&PMO
nanohybrids,
with
NIR-II
photothermal
properties,
employed
as
light-driven
nanomotors.
By
precisely
controlling
CuSe
nanostructure,
these
achieved
optimal
self-propulsion,
thus
cellular
uptake
promoting
tumor
penetration.
Furthermore,
high
loading
capacity
hydrophobic
framework
enabled
incorporation
disulfiram,
thereby
significantly
boosting
efficacy
synergistic
active-motion
therapy.
Advanced Optical Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 31, 2025
Abstract
This
review
explores
the
potential
of
inorganic
nanoscintillators
for
applications
in
detection,
imaging,
and
therapy.
It
begins
by
comparing
scintillation
mechanisms
bulk
materials
versus
nanocrystals,
highlighting
key
differences
related
to
characteristic
interaction
distances.
The
then
focuses
on
synthesis
preparation
doped
insulators,
including
oxides
fluorides,
as
well
semiconductor
quantum
dots.
Finally,
last
section
discusses
various
where
scintillating
nanocrystals
can
offer
significant
advantages.
Advanced Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 9, 2025
Visualizing
weak
NIR
light
is
critical
for
sensing,
imaging,
and
communication,
but
remains
challenging
due
to
inefficient
detection
upconversion
(UC)
mechanisms.
A
smart
NIR-to-visible
photon-UC
organic
optoelectronic
device
reported
that
integrates
photodetection,
light-emitting
diode
(LED),
photovoltaic
capabilities
enable
clear
visualization
of
light.
The
programmable
has
continuous
photodetection
monitoring
the
incident
intensity.
When
intensity
falls
below
a
preset
threshold,
LED
function
automatically
triggered
compensate
UC
emission,
amplifying
visualization.
multifunctional
uses
carefully
designed
ternary
bulk
heterojunction
sensitizer
doped
with
rubrene:DBP
as
emitter.
It
demonstrates
high
efficiency
(>1.5%)
from
808
608
nm,
allowing
without
external
power
under
strong
illumination.
also
shows
excellent
photoresponsivity
0.35
W-1
at
800
nm
specific
detectivity
reaching
10¹2-10¹3
Jones,
enabling
sensitive
low-light
conditions.
exhibits
low
turn-on
voltage
(0.9
V)
luminance
exceeding
1200
cd
m-
2
5
V,
ensuring
energy-efficient
compensation.
Furthermore,
it
achieves
>10%
conversion
efficiency,
sustainable
self-powered
operation.
This
multifunctional,
high-performance
system
offers
great
potential
in
energy
harvesting,
display
technologies.
Advanced Healthcare Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 16, 2025
Abstract
NIR‐II
fluorescence
imaging
has
shown
broad
application
prospects
in
life
science
because
of
its
deeper
tissue
penetration
and
higher
spatiotemporal
resolution.
Developing
fluorophores
with
special
spectroscopic
properties
analytical
functions
become
a
cutting‐edge
but
challenging
topic
this
field.
Herein,
series
azulene‐based
(called
cyazulenes)
adjustable
cycloalkenes
for
applications
is
reported.
Cyazulenes
(CA965,
CA985,
CA1025)
are
constructed
via
the
convenient
coupling
azulene
derivatives.
They
exhibit
different
H‐aggregation
J‐aggregation.
Particularly
noteworthy
that
CA985
can
form
significant
J‐aggregates
strong
sharp
emission
biological
media,
be
used
vivo
blood
vessels
fine
structures
collecting
lymphatics
mice.
Moreover,
displays
passive
bone‐targeted
capacity,
thereby
enabling
bone
imaging.
This
study
demonstrates
chemical
impact
varying
on
aggregate
formation
spectral
cyazulenes,
which
will
advance
fluorophores.
