Emergent Mechanisms in Biocatalysis DOI Creative Commons
Felix C. Raps, Todd K. Hyster

ACS Central Science, Год журнала: 2025, Номер unknown

Опубликована: Июнь 5, 2025

Язык: Английский

Alcohol deoxygenation in the presence of SiO2@FeSO4 nanocomposite DOI Creative Commons

Leyla Bagheri,

Mina Jabbarnejad

Results in Chemistry, Год журнала: 2025, Номер unknown, С. 102320 - 102320

Опубликована: Май 1, 2025

Язык: Английский

Процитировано

0
Nickel-Catalyzed Reductive Coupling of 2-Pyridyl Esters with Unreactivated Alkyl Chlorides: A Universal Synthesis of Aryl-Alkyl and Dialkyl Ketones via Dynamic Halide Exchange DOI
Cong Guo, Zhenying Wang,

Wen-Heng Liu

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

A Ni-catalyzed reductive coupling of 2-pyridyl esters with unactivated primary and secondary alkyl chlorides provides direct access to aryl–alkyl dialkyl ketones. High selectivity can be achieved by rate-matching via dynamic halide exchange.

Язык: Английский

Процитировано

0
Nickel-Catalyzed Adaptive Migration-Enabled Asymmetric Cross-Hydrocarbonylation of Unactivated Alkenes DOI
Yiming Du,

Jia‐Ni Lin,

Yu‐Long Li

и другие.

Journal of the American Chemical Society, Год журнала: 2025, Номер unknown

Опубликована: Май 21, 2025

Transition-metal-catalyzed regio- and enantioselective cross-coupling of alkyl metallic species has emerged as a cornerstone in modern organic synthesis, which enables the construction carbon-carbon carbon-heteroatom bonds with high precision to facilitate rapid access important targets molecular complexity. However, selective formation utilization different intermediates from one precursor under identical conditions remain unknown challenging. Herein, Ni-catalyzed adaptive migratory asymmetric cross-hydroacylation unactivated alkenes for synthesis enantioenriched α-arylated ketones been developed. One alkene serves two by migration, providing most straightforward pathways ketones.

Язык: Английский

Процитировано

0
Iodide/Nickel Co-Catalyzed Manganese-Mediated Denitrogenative Cross-Electrophile Coupling of Benzotriazinones with Alkyl Sulfonates DOI Creative Commons

Yingying Hong,

Xuanxuan Zhang,

Gang Zou

и другие.

Molecules, Год журнала: 2025, Номер 30(11), С. 2397 - 2397

Опубликована: Май 30, 2025

An efficient Ni-catalyzed, Mn-mediated denitrogenative cross-electrophile coupling of N-alkyl-1,2,3-benzotriazinones with alkyl tosylates and mesylates for access to o-alkyl secondary benzamides is reported. The method uses inexpensive non-anhydrous dimethyl acetamide (DMA) in combination tetrabutyl ammonium iodide (TBAI) as a co-catalyst convert sulfonates into iodides situ. Scope limitations the protocol have been demonstrated by >30 examples yields up 91%, showing large electronic effect from N-substituent benzotriazinones. unexpected steric acceleration has observed core benzotriazinones, not only promising highly 2-alkyl-2,3-disubstituted but also shedding light on rate-limiting steps catalytic cycle.

Язык: Английский

Процитировано

0
Emergent Mechanisms in Biocatalysis DOI Creative Commons
Felix C. Raps, Todd K. Hyster

ACS Central Science, Год журнала: 2025, Номер unknown

Опубликована: Июнь 5, 2025

Язык: Английский

Процитировано

0