Discovery of Iodinated Polyfluoroalkyl Acids by Nontarget Mass-Spectrometric Analysis DOI Creative Commons
Caiming Tang,

Yizhe Zhu,

Yutao Liang

и другие.

Опубликована: Сен. 26, 2022

Per- and polyfluoroalkyl acids (PFAAs) including carboxylic sulfonic are a large category of crucial environmental pollutants global concern. Besides known PFAAs, numerous unknown species may exist in the environment, urgently needing discovery characterization. This study implemented nontarget analysis for group novel PFAA pollutants, viz. iodinated PFAAs (I-PFAAs) wastewater by liquid chromatography-high-resolution mass spectrometry combination with an iodine-specific data-processing algorithm. The algorithm took into account diagnostic fragment iodine ion (I–) together carbon sulfur isotopologue distributions. In total, 21 I-PFAA formulas involving 24 congeners were identified. Semiquantification was conducted, total concentrations I-PFAAs 1.9-311.9 ng/mL, indicating non-negligible pollution wastewater. determined along predicted behaviors toxicities demonstrate that merit further in-depth investigation. analytical method instrumental can be extended to screening identification other matrices. Furthermore, results first time provide cognition on occurrence features status environment.

Язык: Английский

Screening (ant)agonistic activities of xenobiotics on the retinoic acid receptor alpha (RARα) using in vitro and in silico analysis DOI
Jiahui Su, Xiaoxi Yang, Hanqing Xu

и другие.

The Science of The Total Environment, Год журнала: 2024, Номер 947, С. 174717 - 174717

Опубликована: Окт. 1, 2024

Язык: Английский

Процитировано

1

Endowing deep eutectic solvent with neutral and ionizable perfluoroalkyl substances extracting capability: experimental study and ab initio molecular dynamics simulation DOI Creative Commons
Chen Fan, Yuwei Shan,

Linru Cheng

и другие.

Green Chemistry Letters and Reviews, Год журнала: 2024, Номер 18(1)

Опубликована: Дек. 11, 2024

The simultaneous separation of neutral and ionizable perfluoroalkyl substances (PFASs) is challenging. traditional solvents used for this purpose are toxic harmful. Deep eutectic (DESs) as sustainable alternatives to reagents have received considerable attention in current research. In work, an array complementary experimental (liquid–liquid equilibrium experiments) computational (ab initio molecular dynamics, AIMD) techniques were utilized explore the distinct distribution behaviors, complicated interaction network, corresponding mechanisms from multidimensional temporal spatial perspectives. proposed bromophenylcyanide-based solvent systems exhibited good extraction performance both PFASs. presence a cyano group adjacent bromine leads increased polarization C–Br bond, resulting strength Br···F contact, which provides selectivity some extent. For fatty acids, their disruptive effect on greater because relatively strong aggregation that affects DES structuring. PFASs, different categories target monomers confined cavities interact with surrounding through abundant sites (such electrostatic attraction, N-H···F-C, O-H···F-C, O-H···O-H, C≡N···O-H hydrogen bonds) without significantly disrupting structural properties by reducing mobility.

Язык: Английский

Процитировано

1

Triclosan Induces Neurodevelopmental Toxicity Mediated by Circrna266/Mir-214 Regulatory Networks in Larval Zebrafish DOI
Huili Wang, Zejun Wang, Xiaowen Han

и другие.

Опубликована: Янв. 1, 2024

Язык: Английский

Процитировано

0

Early-Life Exposure to Methyl Ester Sulfonate Induces Autism-Like Behavioral Deficits in Mice by Disrupting Neuronal Differentiation Via Notch/Hes Signaling DOI
Liehai Hu, Rende Mu,

Yunhui Xia

и другие.

Опубликована: Янв. 1, 2024

Язык: Английский

Процитировано

0

Growing Knowledge of Stem Cells as a Novel Experimental Model in Developmental Toxicological Studies DOI
Zhihua Ren, Tingting Ku,

Mengyao Ren

и другие.

Chemical Research in Chinese Universities, Год журнала: 2023, Номер 39(3), С. 342 - 360

Опубликована: Май 11, 2023

Язык: Английский

Процитировано

0

Endocrine disrupting chemicals: New risk factors for embryonic neurodevelopment DOI Creative Commons
Zhihua Ren,

Mengyao Ren,

Zhendong Sun

и другие.

Ecotoxicology and Environmental Safety, Год журнала: 2023, Номер 268, С. 115668 - 115668

Опубликована: Ноя. 16, 2023

Язык: Английский

Процитировано

0

Discovery of Iodinated Polyfluoroalkyl Acids by Nontarget Mass-Spectrometric Analysis DOI Creative Commons
Caiming Tang,

Yizhe Zhu,

Yutao Liang

и другие.

Опубликована: Сен. 26, 2022

Per- and polyfluoroalkyl acids (PFAAs) including carboxylic sulfonic are a large category of crucial environmental pollutants global concern. Besides known PFAAs, numerous unknown species may exist in the environment, urgently needing discovery characterization. This study implemented nontarget analysis for group novel PFAA pollutants, viz. iodinated PFAAs (I-PFAAs) wastewater by liquid chromatography-high-resolution mass spectrometry combination with an iodine-specific data-processing algorithm. The algorithm took into account diagnostic fragment iodine ion (I–) together carbon sulfur isotopologue distributions. In total, 21 I-PFAA formulas involving 24 congeners were identified. Semiquantification was conducted, total concentrations I-PFAAs 1.9-311.9 ng/mL, indicating non-negligible pollution wastewater. determined along predicted behaviors toxicities demonstrate that merit further in-depth investigation. analytical method instrumental can be extended to screening identification other matrices. Furthermore, results first time provide cognition on occurrence features status environment.

Язык: Английский

Процитировано

0