Identification of Novel Iodinated Polyfluoroalkyl Ether Acids and Other Emerging PFAS in Soils Using a Nontargeted Molecular Network Approach DOI

Yuyan Ji,

Yitao Pan,

Xiaoting Miao

и другие.

Environmental Science & Technology, Год журнала: 2024, Номер unknown

Опубликована: Дек. 31, 2024

Despite advancements in high-resolution screening techniques, the identification of novel perfluoroalkyl and polyfluoroalkyl substances (PFAS) remains challenging without prior structural information. In view this, we proposed implemented a new data-driven algorithm to calculate spectral similarity among PFAS, facilitating generation molecular networks screen for unknown compounds. Using this approach, 81 PFAS across 12 distinct classes were identified soil samples collected near an industrial park Shandong Province, China, including first reported occurrence iodine-substituted PFAS. Among them, standards four polyfluorinated ether sulfonates (I-PFESA) successfully synthesized, enabling confirmation subsequent quantitative analysis. Although median concentration ∑I-PFESA (0.74 ng/g dw) was lower than that ∑H-PFESA (hydrogen-substituted, 61.96 ∑Cl-PFESA (chlorine-substituted, 2.98 dw), embryotoxicity assays zebrafish revealed 6:2 I-PFESA exhibited greater toxicity compared Cl-PFESA same chain length. This highlights need closer examination toxic effects I-PFESA. Notably, algorithm, based on similarity, provides perspectives environmental behavior transformation I-PFESA, although further investigation is required elucidate underlying mechanisms their toxicity.

Язык: Английский

Unraveling the Exposure Spectrum of PFAS in Fluorochemical Occupational Workers: Structural Diversity, Temporal Trends, and Risk Prioritization DOI
Yanna Liu, Yunhe Guo,

Meilin Lv

и другие.

Environmental Science & Technology, Год журнала: 2025, Номер unknown

Опубликована: Март 18, 2025

Despite extensive poly/perfluoroalkyl substance (PFAS) discovery studies in various samples, the exposure spectrum fluorochemical occupational workers remains largely unexplored. Here, serum samples from 28 at a facility were analyzed using nontarget techniques, identifying 64 PFAS classes, including 15 novel ones such as pentafluorosulfur ether-substituted perfluoroalkyl sulfonic acids, hydrogen-substituted perfluoroalkylamines, and perfluoroalkylsulfonyl protocatechualdehyde esters. Temporal trend analyses (2008–2018) revealed stable levels for most but an increase perfluorobutanoic acid (PFBA) perfluorohexanesulfonic (PFHxS), suggesting industrial shifts long-chain to short-chain homologues China since early 2010s. Commonly reported structurally modified (e.g., hydrogen/carbonyl/chlorine substitution, ether insertion, unsaturation) likely historical byproducts of legacy production rather than intentionally manufactured alternatives. A Toxicological Priority Index-based risk assessment, integrating mobility, persistence, bioaccumulation indices, identified di(perfluoroakyl sulfonyl)imides, acids/carboxylic perfluoroalkylsulfonamidoacetic acids high-risk chemicals. Overall, exhibited higher mobility lower persistence PFAS, except chlorinated variants, which showed increased potential. This study highlights critical gaps historically emitted emphasizes need large-scale monitoring assessments manage emerging PFAS.

Язык: Английский

Процитировано

0
Emerging and legacy perfluoroalkyl and polyfluoroalkyl substances (PFAS) in surface water around three international airports in China DOI
Jing Liu, Zhen Zhao, Jie Li

и другие.

Chemosphere, Год журнала: 2023, Номер 344, С. 140360 - 140360

Опубликована: Окт. 9, 2023

Язык: Английский

Процитировано

9
Comparative Analysis of UV-initiated ARPs for Degradation of the Emerging Substitute of Perfluorinated Compounds: Does Defluorination Mean the Sole Factor? DOI
Han Wu, Jingquan Wang, Erdeng Du

и другие.

Journal of Hazardous Materials, Год журнала: 2024, Номер 474, С. 134687 - 134687

Опубликована: Май 21, 2024

Язык: Английский

Процитировано

3
Programming of a Portable Digital Monitoring System-Integrated DNA Aptamer Reversely Regulated Oxidase-Like Nanozyme for Real-Time Dynamic Analysis of Atmospheric Perfluorooctanoic Acid DOI

Chao Nie,

Jiaxu Shui,

Liang Huang

и другие.

Analytical Chemistry, Год журнала: 2024, Номер 96(33), С. 13512 - 13521

Опубликована: Авг. 7, 2024

Timely and efficient analysis of the fluorinated per- polyfluoroalkyl substances (PFAS) in an atmospheric environment is critical to environmental pollution traceability, early warnings, governance. Here, a portable, reliable, intelligent digital monitoring device for onsite real-time dynamic perfluorooctanoic acid (PFOA) proposed. The sensing mechanism attributed oxidase-like activity PtCoNPs@g-C3N4 that reversely regulated by surface modification PFOA-recognizable DNA aptamer, engineering PFOA-activated nanozyme (Apt-PtCoNPs@g-C3N4) combine nonfluorescence o-phenylenediamine (OPD) as dual-modality response system. present PFOA interacts with its aptamer dissociates from Apt-PtCoNPs@g-C3N4, restoring oxidize OPD into yellow fluorescence 2,3-diphenylaniline (DAP), thereby observing PFOA-triggered colorimetric well change. Then, hydrogel kit-programmed Apt-PtCoNPs@g-C3N4 + system used sensitive element incorporate this homemade portable device, automatically gathering processing image gray values our self-weaving software, ultimately realizing surrounding fluorochemical production plant. This work provides direction theoretical foundation designing screening devices cater other contaminants detection requirements.

Язык: Английский

Процитировано

2
Comprehensive characterization and prioritization of halogenated organic compounds in fish and their implications for exposure DOI Creative Commons
Caiming Tang, Ling Liu,

Ruifen Zheng

и другие.

Environment International, Год журнала: 2024, Номер 184, С. 108476 - 108476

Опубликована: Фев. 1, 2024

Fish are an important pollution indicator for biomonitoring of halogenated organic compounds (HOCs) in aquatic environments, and HOCs fish may pose health threats to consumers. This study performed nontarget comprehensive analyses from e-waste recycling zone by gas chromatography-high-resolution mass spectrometry, further prioritized their human exposure risks. A total 1652 formulas were found the fish, which 1222, 117, 313 organochlorines, organobromines, organochlorine-bromines, respectively. The concentrations 15.4-18.7 μg/g (wet weight), organobromines predominant (14.1-16.8 μg/g). Of HOCs, 41 % elucidated with tentative structures divided into 13 groups. estimated daily exposures via dietary consumption local adult residents 3082-3744 ng/kg bw/day. dominated several groups following contribution order: polyhalogenated biphenyls derivatives > diphenyl ethers halo- (H-)alkanes/olefines H-benzenes H-dioxins H-polycyclic aromatic hydrocarbons H-phenols. characterization prioritization results provide overview species distributions edible propose inventory crucial associated high

Язык: Английский

Процитировано

2
Comprehensive Characterization of the Transformation of Wastewater Effluent via Advanced Oxidation Processes Using Nontarget Mass Spectrometric Analysis DOI
Jihong Xu, Yue Song, Xuan Jia

и другие.

ACS ES&T Water, Год журнала: 2024, Номер 4(4), С. 1720 - 1729

Опубликована: Фев. 23, 2024

Advanced oxidation processes (AOPs) have been extensively studied, employing preselected target compounds to evaluate their performance; however, this might overestimate performance in real water. Herein, we applied nontarget mass spectrometric analysis characterize the transformation of wastewater effluent during UV/H2O2 and UV/peroxydisulfate (PDS) processes. A total 8,986 detected features, including 169 identified micropollutants, were categorized as stable unstable products (TPs) based on behaviors. Approximately 40% features resistant both AOPs, highlighting need for additional treatment. The process eliminated a wider range organic than UV/PDS with participation H2O2-related nonradical reactive species, while exhibited high selectivity degrading at faster rate. Oxygen addition dealkyl group reactions most common reaction types AOPs. Linkage four representative toxic TPs implied higher probability yielding high-toxicity compared process. This study provides comprehensive view two AOPs is helpful improving understanding treating effluent.

Язык: Английский

Процитировано

1
Nontarget analysis and characterization of p-phenylenediamine-quinones and -phenols in tire rubbers by LC-HRMS and chemical species-specific algorithm DOI
Caiming Tang,

Yizhe Zhu,

Ruifen Zheng

и другие.

Analytica Chimica Acta, Год журнала: 2024, Номер 1326, С. 343123 - 343123

Опубликована: Авг. 22, 2024

Язык: Английский

Процитировано

1
Latest trends in the environmental analysis of PFAS including nontarget analysis and EOF-, AOF-, and TOP-based methodologies DOI
Mujtaba Baqar, Hao Chen, Yiming Yao

и другие.

Analytical and Bioanalytical Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 21, 2024

Язык: Английский

Процитировано

0
Identification of Novel Iodinated Polyfluoroalkyl Ether Acids and Other Emerging PFAS in Soils Using a Nontargeted Molecular Network Approach DOI

Yuyan Ji,

Yitao Pan,

Xiaoting Miao

и другие.

Environmental Science & Technology, Год журнала: 2024, Номер unknown

Опубликована: Дек. 31, 2024

Despite advancements in high-resolution screening techniques, the identification of novel perfluoroalkyl and polyfluoroalkyl substances (PFAS) remains challenging without prior structural information. In view this, we proposed implemented a new data-driven algorithm to calculate spectral similarity among PFAS, facilitating generation molecular networks screen for unknown compounds. Using this approach, 81 PFAS across 12 distinct classes were identified soil samples collected near an industrial park Shandong Province, China, including first reported occurrence iodine-substituted PFAS. Among them, standards four polyfluorinated ether sulfonates (I-PFESA) successfully synthesized, enabling confirmation subsequent quantitative analysis. Although median concentration ∑I-PFESA (0.74 ng/g dw) was lower than that ∑H-PFESA (hydrogen-substituted, 61.96 ∑Cl-PFESA (chlorine-substituted, 2.98 dw), embryotoxicity assays zebrafish revealed 6:2 I-PFESA exhibited greater toxicity compared Cl-PFESA same chain length. This highlights need closer examination toxic effects I-PFESA. Notably, algorithm, based on similarity, provides perspectives environmental behavior transformation I-PFESA, although further investigation is required elucidate underlying mechanisms their toxicity.

Язык: Английский

Процитировано

0