Environmental Science & Technology,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 21, 2024
Microplastic
(MP),
an
emerging
pollutant,
has
been
identified
as
a
critical
target
in
tackling
plastic
pollution.
Although
plethora
of
studies
have
explored
MP
generation
from
various
sources,
limited
attention
paid
to
processing.
This
study
investigated
(10
μm–5
mm)
virgin
and
waste
extrusion
MPs
at
density
2.13
×
105–9.79
107
(approximately
0.01–10.85
g)
were
generated
when
processing
1
t
plastic.
Feedstock
polymer
types,
pelletizing
techniques
found
influence
the
process.
With
moderate
weight
(270.58–527.34
t)
but
enormous
amount
(1.34
1016–2.63
1016)
globally
2022,
is
underestimated
vital
source
MPs,
emphasizing
need
for
inspection
appropriate
removal
technologies
industry,
especially
water
ring
pelletizing.
Further
simulation
indicated
that
up
84.35%
could
be
removed
using
commonly
available
materials
facility,
with
higher
efficiency
larger-sized
particles.
In
this
regard,
recycling
was
superior
fewer
generated,
which
facilitate
should
fostered.
Environment International,
Год журнала:
2024,
Номер
188, С. 108740 - 108740
Опубликована: Май 11, 2024
The
intensification
of
microplastics
(MPs)
pollution
has
emerged
as
a
formidable
environmental
challenge,
with
profound
global
implications.
pervasive
presence
MPs
across
multitude
mediums,
such
the
atmosphere,
soil,
and
oceans,
extends
to
commonplace
items,
culminating
in
widespread
human
ingestion
accumulation
via
channels
like
food,
water,
air.
In
domestic
realm,
kitchens
have
become
significant
epicenters
for
pollution.
A
plethora
kitchen
utensils,
encompassing
coated
non-stick
pans,
plastic
cutting
boards,
disposable
are
known
release
substantial
quantities
particles
everyday
use,
which
can
then
be
ingested
alongside
food.
This
paper
conducts
thorough
examination
contemporary
research
addressing
from
utensils
during
usage
focuses
on
health
risks
associated
ingestion,
well
myriad
factors
influencing
utensils.
Leveraging
insights
derived
this
analysis,
proposes
series
strategic
recommendations
measures
targeted
at
mitigating
production
settings.
These
initiatives
designed
not
solely
diminish
but
also
enhance
public
awareness
regarding
pressing
concern.
By
adopting
more
informed
practices
kitchens,
we
significantly
contribute
reduction
burden
pollution,
thus
safeguarding
both
ecological
system.
Environmental Science & Technology,
Год журнала:
2024,
Номер
58(27), С. 11901 - 11911
Опубликована: Июнь 26, 2024
Health
risks
of
microplastic
exposure
have
drawn
growing
global
concerns
due
to
the
widespread
distribution
microplastics
in
environment.
However,
more
evidence
is
needed
understand
characteristics
owing
limitation
current
spectrum
technologies,
especially
missing
information
on
small-sized
particles.
In
present
study,
laser
direct
infrared
spectroscopy
and
thermal
desorption-gas
chromatography-mass
spectrometry
combined
pyrolysis
using
a
tubular
furnace
(TD-GC/MS)
were
employed
comprehensively
detect
presence
plastic
particles
down
0.22
μm
human
excreted
samples.
The
results
showed
that
polyethylene
(PE),
polyvinyl
chloride,
PE
terephthalate
(PET),
polypropylene
dominated
large-sized
(>20
μm)
plastics
(0.22-20
feces
urine.
Moreover,
fragments
accounted
for
60.71
60.37%
urine,
respectively,
representing
most
pervasive
shape
excretion.
Surprisingly,
concentration
was
significantly
higher
than
microplastics,
accounting
56.54
50.07%
(345.58
μg/g)
urine
(6.49
μg/mL).
Significant
positive
correlations
observed
between
level
use
containers
consumption
aquatic
products
(Spearman
correlation
analysis,
The
ubiquitous
presence
of
micro
and
nanoplastics
(MNPs)
in
the
environment
has
become
a
pressing
global
concern,
particularly
regarding
potential
impacts
on
human
health.
This
review
underscores
urgent
need
for
an
integrative
research
framework
that
bridges
gap
between
epidemiological
observations
toxicological
insights.
Human
exposure
to
MNPs
occurs
predominantly
through
ingestion,
inhalation
dermal
contact
pathways.
Epidemiological
findings
have
consistently
demonstrated
diverse
tissues,
signaling
broad
emphasizing
imperative
explore
health
risks.
Population
surveys
shown
concentration
feces
people
using
disposable
plastic
tableware
reaches
24.65
items/g.
These
results
are
associated
with
changes
microbiota
composition
metabolite
levels
relevant
central
nervous
system
disorders,
energy
metabolism
inflammatory
responses.
detectable
abundance
nasal
mucus
individuals
wearing
N95
masks
was
measured
be
10.6
±
2.3
items/mg.
Moreover,
population-
based
studies
linked
MNP
adverse
outcomes,
suggesting
correlation
relationships
specific
diseases
such
as
bowel
disease
(IBD)
pulmonary
ground-glass
nodules
(GGN).
associations
underscore
necessity
in-depth
investigations
elucidate
toxicity
mechanisms
MNPs.
Meanwhile,
laboratory-based
reveal
causative
various
vitro
vivo
models
been
used
gastrointestinal
tract,
lungs
cardiovascular
system.
However,
early
failed
reflect
complexity
real
environment.
To
foster
interdisciplinary
collaborations,
this
paper
aims
reconcile
disparities
risks
impacts.
By
critically
reviewing
recent
advancements
understanding
MNPs,
organ-specific
toxicity,
work
furnishes
comprehensive
perspective
implications
Research Square (Research Square),
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 1, 2025
Abstract
The
rise
of
food
delivery
culture
has
resulted
in
millions
tons
food-contact
plastic
containers
being
used
each
year,
yet
the
risks
micro(nano)plastics
(MNPs)
released
during
storage
oil-rich
foods
are
still
not
well
understood.
Here,
we
investigated
MNP
release
from
polypropylene
(PP)
and
polyethylene
(PE)-coated
under
simulated
takeout
scenarios.
When
exposed
to
cooking
oil
microwave
heating,
up
125-fold
more
MNPs
471-fold
heavy
metals
compared
water
exposure,
with
significantly
altered
physicochemical
properties.
Oil-derived
PP
NPs,
uniquely
encapsulated
films
positive
surface
charge
(+7.37
mV).
oil-derived
NPs
may
enhance
their
interaction
negatively
charged
cell
membranes,
leading
rapid
death
within
5
minutes
at
a
concentration
100
μg/mL
through
membrane
disruption.
Transcriptomic
analysis
revealed
that
oil-PP
triggered
substantially
extensive
gene
expression
changes
than
water-derived
particularly
pathways
related
acute
cellular
stress
mitochondrial
energy
metabolism.
Global
exposure
assessments
highlight
annual
human
intake
3.35
g
food.
Based
on
integrated
molecular
endpoints,
established
benchmark
dose
lower
limit
(BMDL)
1.18
for
NPs.
abundance
biological
samples
exceeds
BMDL
thresholds,
suggesting
significant
health
risks.
Our
findings
reveal
previously
unknown
mechanisms
toxicity
underscore
urgent
need
stricter
regulation
packaging
foods.
ACS Applied Materials & Interfaces,
Год журнала:
2024,
Номер
16(12), С. 14405 - 14420
Опубликована: Март 15, 2024
Developing
protein
confinement
platforms
is
an
attractive
research
area
that
not
only
promotes
delivery
but
also
can
result
in
artificial
environment
mimicking
of
the
cellular
one,
impacting
both
controlled
release
proteins
and
fundamental
biophysics.
Polymeric
nanoparticles
(PNPs)
are
to
confine
due
their
superior
biocompatibility,
low
cytotoxicity,
controllable
under
external
stimuli.
However,
loading
into
PNPs
be
challenging
potential
structural
perturbation
upon
contacting
interior
PNPs.
In
this
work,
we
developed
a
novel
approach
encapsulate
with
assistance
zeolitic
imidazolate
framework
(ZIF).
Here,
ZIF
offers
additional
protection
layer
target
by
forming
protein@ZIF
composite
via
aqueous-phase
cocrystallization.
We
demonstrated
our
platform
using
model
protein,
lysozyme,
widely
studied
PNP
composed
poly(ethylene
glycol)-poly(lactic-co-glycolic
acid)
(PEG–PLGA).
A
comprehensive
study
standard
tests
as
well
various
spectroscopic
techniques
was
carried
out
on
lysozyme
loaded
onto
PEG–PLGA
without
protection.
As
compared
direct
encapsulation,
prior
offered
enhanced
capacity,
reduced
leaching,
especially
initial
stage,
led
slower
kinetics,
secondary
perturbation.
Meanwhile,
function,
uptake
encapsulated
within
ZIF-bound
systems
decent.
Our
results
use
assisting
encapsulation
established
basis
for
developing
more
sophisticated
combination
materials
diverse
molecular
architectures
disciplines.
such,
anticipate
protein-encapsulated
will
serve
future
polymer
biophysics
biochemistry
biomedical
applications
where
needed
support
therapeutics
and/or
nutrients.
