Hair cortisol stability after 5-year storage: Insights from a sample of 17-year-old adolescents DOI Creative Commons

Éloise Berger,

Helen Findlay,

Charles–Édouard Giguère

и другие.

Comprehensive Psychoneuroendocrinology, Год журнала: 2024, Номер 18, С. 100234 - 100234

Опубликована: Апрель 17, 2024

Hair has become an increasingly valuable medium to investigate the association between chronic stress, stable differences in systemic cortisol secretion and later health. Assessing hair many advantages, notably its non-invasive retrospective nature, need for a single biospecimen convenient storage until analysis. However, few studies offered empirical evidence documenting long-term temporal stability of concentration (HCC) prior analysis, especially humans. Yet, knowing how long samples can be stored without compromising accuracy measurement is crucial importance when planning data collection This study examined HCC assayed twice, five years apart.

Язык: Английский

Early-life exposure to mixtures of Endocrine-Disrupting Chemicals and a Multi-domain Health Score in preschool children DOI
Ines Amine, Alicia Guillien, Sam Bayat

и другие.

Environmental Research, Год журнала: 2025, Номер 272, С. 121173 - 121173

Опубликована: Фев. 22, 2025

Язык: Английский

Процитировано

0
How Indoor Decoration Materials Contribute to Phthalates Pollution: Uncovering Occurrences, Sources, and Their Implications for Environmental Burdens in Households DOI

Hangjia Shen,

Ying Zhang,

Xinyu Lu

и другие.

Journal of Hazardous Materials, Год журнала: 2025, Номер 490, С. 137719 - 137719

Опубликована: Фев. 25, 2025

Язык: Английский

Процитировано

0
The impact of endocrine disrupting chemicals on adrenal corticosteroids – a systematic review of epidemiological studies DOI Creative Commons
Isabel Stüfchen, Júnia Ribeiro de Oliveira Longo Schweizer,

Friederike Völter

и другие.

Environmental Research, Год журнала: 2025, Номер unknown, С. 121438 - 121438

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0
Prenatal phthalate exposure and anogenital distance in infants at 12 months DOI Creative Commons
Kim N. Cajachagua‐Torres,

Nicole B. Salvi,

Eunsil Seok

и другие.

Environment International, Год журнала: 2025, Номер 199, С. 109472 - 109472

Опубликована: Апрель 15, 2025

Anogenital distance (AGD) is a postnatal marker of in utero exposure to androgens and anti-androgens, predictor reproductive health. We examined the association between gestational phthalates AGD male female infants. In 506 mother-infant pairs (276 males, 230 females), we measured urinary concentrations phthalate metabolites at < 18 18-25 weeks gestation child age 12.9 months (95 % range 11.4-21.1). Phthalate metabolite were adjusted for dilution, averaged, natural log-transformed. anus-clitoris (AGDac) anus-fourchette (AGDaf) females, anus-scrotum distance, anus-penis penile width males. used linear regression partial-linear single-index (PLSI) models examine associations as single pollutants mixture. Fifty-eight percent mothers Hispanic, followed by 27 non-Hispanic White. Higher exposures ∑di-isononyl(phthalate) (∑DiNP) was associated with longer AGDaf [1.28 mm confidence interval [CI]: 0.52, 2.03) 0.97 %CI: 0.25, 1.69), respectively]. ∑di(2-ethylhexyl)phthalate (∑DEHP) AGDac [2.80 1.17, 4.44), 1.90 0.76, 3.04), No observed males after multiple testing correction. mixture analyses, ∑DiNP ∑DEHP main contributors females. also detected an interaction Early pregnancy Biological mechanisms underlying these should be further investigated.

Язык: Английский

Процитировано

0
Associations between Urinary Phthalate Metabolites with BDNF and Behavioral Function among European Children from Five HBM4EU Aligned Studies DOI Creative Commons
Elena Salamanca‐Fernández, Lydia Espín-Moreno, Alicia Olivas-Martínez

и другие.

Toxics, Год журнала: 2024, Номер 12(9), С. 642 - 642

Опубликована: Авг. 31, 2024

Based on toxicological evidence, children’s exposure to phthalates may contribute altered neurodevelopment and abnormal regulation of brain-derived neurotrophic factor (BDNF). We analyzed data from five aligned studies the Human Biomonitoring for Europe (HBM4EU) project. Ten phthalate metabolites protein BDNF levels were measured in urine samples 1148 children aged 6–12 years Italy (NACII-IT cohort), Slovakia (PCB-SK Hungary (InAirQ-HU cohort) Norway (NEBII-NO). Serum was also available 124 Slovenian (CRP-SLO cohort). Children’s total, externalizing internalizing behavioral problems assessed using Child Behavior Checklist at 7 age (only NACII-IT Adjusted linear negative binomial regression models fitted, together with weighted quantile sum (WQS) assess mixture associations. Results showed that, boys but not girls cohort, each natural-log-unit increase mono-n-butyl (MnBP) Mono(2-ethyl-5-oxohexyl) (MEOHP) cross-sectionally associated higher [incidence rate ratio (IRR): 1.20; 95% CI: 1.02, 1.42 1.26; 1.03, 1.55, respectively]. A suggestive association observed per tertile whole population (WQS—IRR = 1.15; 0.97, 1.36) (IRR 0.96, 1.49). In NACII-IT, PCB-SK, InAirQ-HU NEBII-NO cohorts together, urinary strongly levels, WQS confirming a (percent change (PC) 25.9%; 17.6, 34.7), (PC 18.6%; 7.92, 30.5) mainly among 36.0%; 24.3, 48.9). Among CRP-SLO boys, ∑DINCH concentration lower serum (PC: −8.8%; −16.7, −0.3). predicted worse scores all (IRR: 1.00, 1.32). suggest that (1) di-n-butyl (DnBP) di(2-ethylhexyl) (DEHP) is more (2) DINCH associate systemic (3) concentrations (although caution needed since possibility “urine bias” could explain these associations noncausal terms identified) (4) predict problems. Given this first study examine relationship between metabolite biomarkers, future are validate

Язык: Английский

Процитировано

1
Exposure to Synthetic Endocrine-Disrupting Chemicals in Relation to Maternal and Fetal Sex Steroid Hormones: A Scoping Review DOI Creative Commons
Megan Hansel,

Abigail M Rosenberg,

Carolyn Waugh Kinkade

и другие.

Current Environmental Health Reports, Год журнала: 2024, Номер 11(3), С. 356 - 379

Опубликована: Июль 22, 2024

Many synthetic endocrine-disrupting chemicals (EDCs) are ubiquitous in the environment and highly detected among pregnant people. These may disrupt maternal and/or fetal sex steroid hormones, which critical to pregnancy maintenance development. Here, we review epidemiological literature examining prenatal exposure common EDCs relation hormones.

Язык: Английский

Процитировано

1
Prenatal exposure to synthetic chemicals in relation to HPA axis activity: A systematic review of the epidemiological literature DOI Creative Commons

Ambuja Pande,

Carolyn Waugh Kinkade,

Nashae Prout

и другие.

The Science of The Total Environment, Год журнала: 2024, Номер 956, С. 177300 - 177300

Опубликована: Ноя. 8, 2024

Pregnant people are widely exposed to numerous synthetic chemicals with known endocrine-disrupting properties (e.g., phthalates, phenols, per- and poly-fluoroalkyl substances (PFAS)). To date, most epidemiological research on how (EDCs) disrupt hormone pathways has focused estrogens, androgens, thyroid hormones. Far less examined the impact of EDCs hypothalamic-pituitary-adrenal (HPA) axis, despite its central role in physiologic stress response metabolic function.

Язык: Английский

Процитировано

1
Hair cortisol stability after 5-year storage: Insights from a sample of 17-year-old adolescents DOI Creative Commons

Éloise Berger,

Helen Findlay,

Charles–Édouard Giguère

и другие.

Comprehensive Psychoneuroendocrinology, Год журнала: 2024, Номер 18, С. 100234 - 100234

Опубликована: Апрель 17, 2024

Hair has become an increasingly valuable medium to investigate the association between chronic stress, stable differences in systemic cortisol secretion and later health. Assessing hair many advantages, notably its non-invasive retrospective nature, need for a single biospecimen convenient storage until analysis. However, few studies offered empirical evidence documenting long-term temporal stability of concentration (HCC) prior analysis, especially humans. Yet, knowing how long samples can be stored without compromising accuracy measurement is crucial importance when planning data collection This study examined HCC assayed twice, five years apart.

Язык: Английский

Процитировано

0