Developmental toxicity of formulated insecticide mixture containing imidacloprid and beta-cyfluthrin in fish: Insights using zebrafish

Chemosphere, Год журнала: 2025, Номер 377, С. 144314 - 144314

Опубликована: Март 25, 2025

Язык: Английский

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Nontargeted screening of contaminants of emerging concern in the Nandu River Estuary

Marine Pollution Bulletin, Год журнала: 2025, Номер 215, С. 117870 - 117870

Опубликована: Март 28, 2025

Язык: Английский

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New Psychoactive Substance Esketamine Causes Endocrine-Disrupting Effects and Developmental Toxicity

Environmental Science & Technology, Год журнала: 2025, Номер unknown

Опубликована: Апрель 22, 2025

Esketamine (ESK), a new psychoactive substance known for its strong hallucinogenic effect, has been detected in surface water worldwide. The toxicity of ESK to fish at certain environmental concentration remains unclear. In this study, zebrafish embryos and ZF4 cells were exposed (0, 0.12, 1.02, 10.6 μg L-1, marked by SC, LC, MC, HC, respectively) 14 days post fertilization (dpf) 24 h, respectively. Biphasic dose responses induced observed after h exposure. ESK-LC ESK-MC obviously increased embryo area length, height, volume yolk sac, whereas ESK-HC had the opposite effect. appreciably upregulated transcription expression levels vtg, disrupting cell cycle After dpf exposure, KEGG analysis indicated that circadian rhythm, nucleotide excision repair, estrogen signaling pathways top three impacted pathways, with significantly enhancing gene these except cyp7a1 bh1he41. Correspondingly, notably VTG level, aligning relatively high affinity receptors, as analyzed through molecular docking. Our research demonstrated exhibits developmental endocrine-disrupting effects zebrafish, highlighting need address ecological fish.

Язык: Английский

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Prenatal exposure to neonicotinoid insecticides, fetal endocrine hormones and birth size: Findings from SMBCS

Environment International, Год журнала: 2024, Номер 193, С. 109111 - 109111

Опубликована: Окт. 31, 2024

Язык: Английский

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Effects of Insecticide and Herbicides on Thyroid Disturbances in Zebrafish

Toxics, Год журнала: 2024, Номер 12(8), С. 570 - 570

Опубликована: Авг. 3, 2024

Thyroid cancer usually begins with thyroid dysfunction and nodules has become the most common globally, especially in women. Although causes of are complex, presence environmental pollutants, certain pesticides as established mutagens, been widely accepted. Zebrafish (

Язык: Английский

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Long-term Exposure to Emamectin Benzoate Impairs Reproductive Health in Adult Zebrafish and Alters Neurodevelopment in Their Offspring

Journal of Hazardous Materials, Год журнала: 2024, Номер 486, С. 137007 - 137007

Опубликована: Дек. 31, 2024

Язык: Английский

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Insights into organophosphorus insecticide malathion induced reproductive toxicity and intergenerational effect in zebrafish (Danio rerio)

The Science of The Total Environment, Год журнала: 2024, Номер 959, С. 178188 - 178188

Опубликована: Дек. 21, 2024

Язык: Английский

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Effect of early rearing conditions on the behaviour and microbiome of fish with low genetic diversity

Опубликована: Июль 23, 2024

Fish performance is influenced by their genotype and environment. For populations with low genetic diversity, adaptation to environmental change can be compromised, but it has been suggested that the microbiome act as an additional source of variability. Early rearing conditions particularly important for fish development behaviour, due dependence on conditions. This thesis explored interactions between environment (diet enrichment) metabolic rate (gut, skin) using captive wild naturally inbred mangrove killifishes (Kryptolebias sp.), where exploratory behaviour closed respirometry were used test killifish diversity analyses performed in both killifishes. Behavioural trials self-fertilizing marmoratus) indicated a significant effect strain (environmental enrichment diet) activity measurements. Incubation time also had substantial role diversity. Gut-microbiome alpha was shaped strain, diet, hatching K. marmoratus diet physical enrichment. An intergenerational influence detected K.armoratus, parental found offspring activity. Gut-microbial comparisons parents identified Vibrionaceae dominant colonizers laboratory reared marmoratus. A over composition distribution observed. The interaction own environments suggests long-term effects (gut) microbiome. In wild, results from outcrossing ocelatus self-fertilising hermaphroditus community skin strongly species host at different levels. study first-time evidence relationship epigenetic these populations, suggesting mechanisms could potential sources variability global findings this origins (laboratory natural conditions) highlighted importance shaping

Язык: Английский

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Evaluating pulmonary toxicity of PFOS and its alternative OBS using spheroids of A549 cells

The Science of The Total Environment, Год журнала: 2024, Номер 955, С. 176895 - 176895

Опубликована: Окт. 12, 2024

Язык: Английский

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Contamination profile and hazards of neonicotinoid insecticides in honey from apiaries in Beijing, China

Environmental Science and Pollution Research, Год журнала: 2024, Номер 31(51), С. 60959 - 60970

Опубликована: Окт. 14, 2024

Язык: Английский

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