Numeric uptake drives nanoplastic toxicity: Size-effects uncovered by toxicokinetic-toxicodynamic (TKTD) modeling

Journal of Hazardous Materials, Год журнала: 2025, Номер 486, С. 137105 - 137105

Опубликована: Янв. 2, 2025

Язык: Английский

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In Vivo Visualization of Microplastic Degradability and Intestinal Functional Responses in a Plastivore Insect

Journal of Hazardous Materials, Год журнала: 2025, Номер 486, С. 137109 - 137109

Опубликована: Янв. 5, 2025

Язык: Английский

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Marine Micro(nano)plastics Toxicology: Knowledge Gaps and Perspectives

Journal of Hazardous Materials, Год журнала: 2025, Номер unknown, С. 138086 - 138086

Опубликована: Март 1, 2025

Язык: Английский

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Microplastics in Indonesian land and aquatic environment: From research activities to regulation policies

Marine Pollution Bulletin, Год журнала: 2024, Номер 206, С. 116813 - 116813

Опубликована: Авг. 7, 2024

Язык: Английский

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In vivo Bioaccumulation and Responses of Hemocytes of Mussels Perna viridis to Microplastics and Nanoplastics Exposure

Journal of Hazardous Materials, Год журнала: 2024, Номер 480, С. 135939 - 135939

Опубликована: Сен. 23, 2024

Язык: Английский

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Modeling the Vertical Transport of Copepod Fecal Particles under Nano/Microplastic Exposure

Environmental Science & Technology, Год журнала: 2025, Номер unknown

Опубликована: Март 28, 2025

Nano- and microplastics (NMPs) may significantly impact the marine carbon cycle, fecal pellets produced by copepods are crucial for vertical transport. In this study, we investigated effects of NMP size, concentration, diatom supply on production settling copepod Parvocalanus crassirostris. By employing an aggregation-induced emission fluorescence imaging technique, visualized distribution NMPs in pellets, measured their size rate, developed a fluid dynamic model to simulate process water column. Our results indicated that NPs MPs exhibited uniform nonuniform distributions materials, respectively. reduced both integrity pellets. Copepods ingested absence diatoms, but exposure 5000 μg/L decreased pellet 52% presence diatoms due feeding selectivity. The sinking rates varying sizes, as obtained from modeling simulations, ranged 10.9 103.1 m/day. When proportion participating polystyrene (PS) reached 50%, velocity 34%. study provides new insights into transport under pollution.

Язык: Английский

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Passing the Parcels: Intercellular Nanoplastics Transfer in Mussels Perna viridis with Activated Immunomodulation

Environmental Science & Technology, Год журнала: 2025, Номер unknown

Опубликована: Апрель 16, 2025

Nanoplastics (NPs) are generally considered to have a defined intracellular fate, being difficult excrete or transport due their stability. This study provides the first evidence of NPs intercellular transfer in hemocytes green mussels (Perna viridis), which subsequently activated immunomodulation process. were predominantly internalized by granulocytes, with portion translocated and deposited lysosomes, whereas those retained endosomes transferred new (mainly granulocytes). The direction was driven NP concentration gradients. Transfer kinetics size-dependent, smaller-sized exhibiting greater potential but lower rate, primarily specific extracellular vesicle-mediated pathway. Tunneling nanotubes provided most efficient pathway for NPs, as continuous membrane structure allowed direct substance exchange. Crucially, redistribution accompanied gradient-driven mitochondria injured hemocytes. process alleviated stress on overburdened regulated reactive oxygen species production, enhancing phagocytic activity promoting immune responses. These findings underscore that exhibit far more active behavior system than previously understood provide insights into how cells maintain health marine organisms face challenges.

Язык: Английский

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Nanoplastics Transport in Zebrafish Brain: Molecular and Phenotypic Behavioral Impacts

Journal of Hazardous Materials, Год журнала: 2025, Номер unknown, С. 138548 - 138548

Опубликована: Май 1, 2025

Язык: Английский

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Modeling the Differential Functional Responses and Selectivity of a Marine Copepod to Nano/Microplastics in Mixture

Journal of Hazardous Materials, Год журнала: 2024, Номер 480, С. 135805 - 135805

Опубликована: Сен. 10, 2024

Язык: Английский

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Visible Combined Near-Infrared in Situ Imaging Revealed Dynamic Effects of Microplastic Fibers and Beads in Zebrafish

Environmental Science & Technology, Год журнала: 2024, Номер 58(37), С. 16269 - 16281

Опубликована: Авг. 30, 2024

Microplastics (MPs) as emerging contaminants are widely present in the environment and ubiquitously ingested accumulated by aquatic organisms. MPs may be quickly eliminated after a brief retention animals (such digestive tract); thus, understanding damage caused during this process whether can recovered is important. Here, we proposed use of visible light imaging to track combined with near-infrared (NIR) reveal

Язык: Английский

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