Environmental Science & Technology,
Год журнала:
2024,
Номер
58(46), С. 20619 - 20629
Опубликована: Окт. 25, 2024
Antibiotic-induced
inflammation
involves
the
release
of
myeloperoxidase
(MPO),
an
enzyme
whose
expression
in
tissues
is
associated
with
inflammatory
pathway.
However,
existing
methods
for
detecting
MPO
cells
are
limited.
In
this
study,
a
DNAzyme
nanorobot
was
developed
using
scaffold
gold
nanoparticles
(AuNPs)
decorated
functional
strands
and
their
fluorophore-labeled
substrate
strands.
The
remains
inactive
due
to
self-assembled
hairpin
structure,
phosphorothioate
(PT)
modification
inserted
into
stem
domain.
When
present,
it
triggers
halogenation
process
that
generates
hypochlorous
acid
(HClO).
HClO
specifically
catalyzes
cleavage
PT-site,
releasing
free
cleave
substrates
generating
increasing
fluorescent
signal.
detection
limit
its
primary
product,
HClO,
were
determined
be
0.038
μg/mL
0.013
μM,
respectively.
can
readily
introduced
function
autonomously
differentiate
increased
MPO/HClO
levels
caused
by
antibiotics.
This
approach
applied
image
RAW264.7
exposed
four
prevalent
antibiotics
found
environment
(phorbol
12-myristate
13-acetate,
erythromycin,
penicillin,
tetracycline)
as
well
antibiotic
production
wastewater.
offers
novel
strategies
monitoring
evaluate
health
impacts
exposure.
Environmental Science Nano,
Год журнала:
2024,
Номер
11(7), С. 2978 - 2993
Опубликована: Янв. 1, 2024
The
establishment
of
a
heterojunction
holds
significant
promise
for
facilitating
the
separation
and
migration
photogenerated
carriers,
thereby
engendering
robust
photooxidation–reduction
capabilities.
Environmental Science & Technology,
Год журнала:
2024,
Номер
58(26), С. 11661 - 11674
Опубликована: Июнь 14, 2024
This
study
addresses
existing
gaps
in
understanding
the
specific
involvement
of
dissolved
organic
matter
(DOM)
fractions
antibiotic
photolysis,
particularly
under
natural
conditions
and
during
DOM
photobleaching.
Employing
fluorescent,
chemical,
molecular
analysis
techniques,
it
explores
impact
extracellular
intracellular
(EOM
IOM)
on
photodissipation
multiclass
antibiotics,
coupled
with
photobleaching
solar
radiation.
Key
findings
underscore
selective
fractions,
propelled
by
distinct
chemical
profiles,
influencing
DOM-mediated
photolysis.
Notably,
lipid-like
substances
dominate
IOM,
while
lignin-like
prevail
EOM,
each
uniquely
responding
to
sunlight
exhibiting
Sunlight
primarily
targets
fulvic
acid-like
lignin
components
contrasting
initial
changes
observed
tryptophan-like
lipid
IOM.
The
lower
photolability
attributed
its
rich
unsaturated
compounds,
contributes
an
enhanced
rate
indirect
photolysis
(0.339-1.402
h
