Journal of Agricultural and Food Chemistry,
Год журнала:
2025,
Номер
73(9), С. 5092 - 5101
Опубликована: Фев. 24, 2025
This
study
investigates
the
combined
effects
of
polystyrene
nanoplastics
(PS-NPs)
and
deltamethrin
(DEL)
on
mice,
focusing
their
different
impacts
among
organs.
Mice
were
exposed
to
PS-NPs
and/or
DEL
for
30
days.
Results
showed
that
alleviated
DEL-induced
oxidative
damage
in
liver
kidney
by
reducing
its
accumulation
due
decreased
bioaccessibility.
Conversely,
increased
intestine,
leading
enhanced
susceptibility
enteric
infections
caused
bacteria,
viruses,
parasites,
as
indicated
transcriptomic
analysis.
delayed
excretion
gastrointestinal
motility,
evidenced
altered
neurotransmitter
levels,
thereby
contributing
greater
intestinal
DEL.
Moreover,
16S
rDNA
sequencing
revealed
tended
decrease
beneficial
bacteria
increase
pathogenic
gut
microbiota,
further
heightening
upon
coexposure.
The
findings
this
shed
new
light
complex
health
risks
associated
with
coexposure
pesticides.
Heliyon,
Год журнала:
2025,
Номер
11(4), С. e42606 - e42606
Опубликована: Фев. 1, 2025
Microplastic
particles
have
become
ubiquitous
in
various
ecosystems
due
to
a
drastic
increase
plastic
use
and
its
consequent
litter.
The
biological
effects
of
these
on
aquatic
fauna
are
well-documented.
However,
the
study
their
accumulation
subsequent
impact
terrestrial
flora
is
initial
stages.
Furthermore,
favorable
surface
provided
by
plastics
lodges
harmful
substances
pathogens
known
cause
varied
human
physiology.
Notably,
entry
into
gastrointestinal
tract
can
result
ailments,
including
dysbiosis
gut
microflora
microbial
biodiversity.
Moreover,
similar
physiological
ailments
been
observed
humans
action
pathogenic
microorganisms.
Therefore,
this
review,
we
aim
explore
relationship
possible
amplification
pathogenesis
ability
provide
surfaces
for
absorption
biofilm
formation
such
Additionally,
there
exists
possibility
carcinogenesis
coexistence
microbes
micro-and
nanoplastics
synergistic
leading
severe
ailments.
Journal of Agricultural and Food Chemistry,
Год журнала:
2025,
Номер
73(9), С. 5092 - 5101
Опубликована: Фев. 24, 2025
This
study
investigates
the
combined
effects
of
polystyrene
nanoplastics
(PS-NPs)
and
deltamethrin
(DEL)
on
mice,
focusing
their
different
impacts
among
organs.
Mice
were
exposed
to
PS-NPs
and/or
DEL
for
30
days.
Results
showed
that
alleviated
DEL-induced
oxidative
damage
in
liver
kidney
by
reducing
its
accumulation
due
decreased
bioaccessibility.
Conversely,
increased
intestine,
leading
enhanced
susceptibility
enteric
infections
caused
bacteria,
viruses,
parasites,
as
indicated
transcriptomic
analysis.
delayed
excretion
gastrointestinal
motility,
evidenced
altered
neurotransmitter
levels,
thereby
contributing
greater
intestinal
DEL.
Moreover,
16S
rDNA
sequencing
revealed
tended
decrease
beneficial
bacteria
increase
pathogenic
gut
microbiota,
further
heightening
upon
coexposure.
The
findings
this
shed
new
light
complex
health
risks
associated
with
coexposure
pesticides.
