Environmental Science & Technology Letters,
Год журнала:
2024,
Номер
12(1), С. 64 - 72
Опубликована: Дек. 10, 2024
Oxidative
potential
(OP)
is
increasingly
recognized
as
a
more
health-relevant
metric
than
particulate
matter
(PM)
mass
concentration
because
of
its
response
to
varying
chemical
compositions.
Given
the
limited
research
on
OP
complex
combustion
aerosols,
effects
aging
processes
their
remain
underexplored.
We
used
online
instruments
track
evolution
[via
dithiothreitol
(DTT)
assays]
during
wood
burning
and
coal
emissions
by
hydroxyl-radical-driven
photooxidation
dark
ozonolysis.
observed
very
substantial
increases
in
intrinsic
(OPmDTT)
aerosols
(e.g.,
OPmDTT
up
100
pmol
min–1
μg–1
for
OH-aged
emissions)
within
1
day
equivalent
aging.
Further
analysis
relation
degree
oxidation
revealed
generalizing
carbonaceous
with
average
carbon
state
OS¯c
values
ranging
from
−1.5
−0.5
assuming
they
have
constant
value
∼10
±
6
μg–1.
Additionally,
we
uncovered
strong
dependency
both
source/precursor
pathway
above
∼−0.5.
OH
was
identified
an
exceptionally
efficient
generating
highly
oxidized,
multifunctionalized,
DTT-active
products,
particularly
emissions.
Aerosol Science and Technology,
Год журнала:
2024,
Номер
58(10), С. 1093 - 1113
Опубликована: Июль 24, 2024
Exposure
to
biomass-burning
particulate
matter
(PM)
is
associated
with
various
adverse
health
effects,
including
respiratory
and
cardiovascular
conditions,
cancer,
systemic
effects.
Multiple
mechanisms
underlying
PM
toxicity
components
derived
from
biomass
burning
elicit
harmful
such
as
reactive
oxygen
species
(ROS)
generation,
inflammation,
genotoxicity,
tissue-specific
damage.
Specific
compounds
or
families
of
present
in
PM,
polyaromatic
hydrocarbons
(PAHs)
their
derivatives,
have
been
identified
key
contributors
the
observed
Their
roles
oxidative
stress,
DNA
damage,
cell
death
elucidated
organs,
lungs,
liver,
kidneys,
brain,
providing
valuable
insights
into
biological
influence
biomass-burning-related
diseases.
Current
knowledge
impact
highlights
imperative
need
for
further
research
understand
implications
this
environmental
challenge
importance
mitigating
effects
increased
exposure
pollution
protect
well-being
exposed
populations
worldwide.
This
review
focuses
on
crucial
stress
inflammation
mediating
triggered
by
aerosols.
It
examines
aspects
health-related
impacts
emissions,
particularly
those
components.
The
consequences
populations,
emphasizing
specific
biochemical
responses,
contributions
mechanisms,
responsible
these
Aerosol Research,
Год журнала:
2025,
Номер
3(1), С. 205 - 218
Опубликована: Апрель 22, 2025
Abstract.
Air
pollution
is
one
of
the
largest
environmental
health
risks
and
leading
causes
adverse
outcomes
mortality
worldwide.
The
possible
importance
oxidative
potential
(OP)
as
a
metric
to
quantify
particle
toxicity
in
air
increasingly
being
recognised.
In
this
work,
OP
reactive
oxygen
species
(ROS)
activity
particles
from
fresh
aged
petrol
passenger
car
emissions
residential
wood
combustion
(RWC)
were
investigated
using
two
novel
instruments.
Applying
online
instruments
an
ascorbic
acid
(AA)
2′,7′-dichlorodihydrofluorescein
(DCFH)
assay
provides
much
higher
temporal
resolution
compared
with
traditional
filter-based
methods
allows
for
new
insights
into
highly
dynamic
changes
ROS
these
sources.
Due
efficiency
particulate
filter
Euro
6d
car,
almost
no
primary
emitted
and,
thus,
or
was
detected
exhaust.
However,
substantial
ROSs
observed
after
photochemical
ageing
due
formation
secondary
particles.
Increasing
also
when
comparing
RWC
emissions.
Overall,
had
signals
This
suggests
that
could
be
major
contributor
may
intrinsically
more
harmful
emission
source
than
exhaust,
although
still
high.
These
measurements
illustrate
strong
differences
nature
toxicity-relevant
properties
sources
contribute
efficient
mitigation
policies.
Environmental Science Processes & Impacts,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
In
recent
decades,
several
cell-based
and
acellular
methods
have
been
developed
to
evaluate
ambient
particulate
matter
(PM)
toxicity.
Although
provide
a
more
comprehensive
assessment
of
PM
toxicity,
their
results
are
difficult
comprehend
due
the
diversity
in
cellular
endpoints,
cell
types,
assays
interference
chemical
components
with
some
assays'
techniques.
this
review,
we
attempt
clarify
these
issues.
We
first
discuss
morphological
immunological
differences
among
various
macrophage
epithelial
cells,
belonging
respiratory
systems
human
murine
species,
used
ACS ES&T Air,
Год журнала:
2024,
Номер
2(1), С. 109 - 118
Опубликована: Дек. 6, 2024
Quantifying
changes
in
the
properties
of
smoke
aerosols
under
varying
conditions
is
important
for
understanding
health
and
environmental
impacts
exposure
to
smoke.
Smoke
composition,
aerosol
liquid
water
content,
effective
density
(ρeff),
other
can
change
significantly
as
travels
through
areas
different
ambient
over
time.
During
this
study,
we
measured
composition
physical
due
oxidative
aging
humidity.
We
found
that
led
SOA
formation
increases
ratios
organic
carbon
elemental
carbon.
Aerosol
content
increased
with
increasing
relative
humidity
(RH),
aged
took
up
more
than
fresh
at
all
levels,
likely
a
combination
surface
polarity
low
medium
RH
area
high
RH.
Growth
factors
ranged
from
1.06
±
0.08
1.32
Oxidative
ρeff.
For
100
nm
particles,
ρeff
∼1.2
∼1.6
Results
these
experiments
suggest
leads
restructuring
compaction
and/or
chemistry.
