Two approaches to mass closure analysis for carbon-rich aerosol in Metro Manila, Philippines

Environmental Science Atmospheres, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

We characterized PM in Metro Manila, highlighting high contribution of carbonaceous species and ultrafine particles, achieved mass closure.

Язык: Английский

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Formation of Ozone and PM_2.5 in Smoke from Prescribed Burning in the Southeastern United States

ACS ES&T Air, Год журнала: 2025, Номер unknown

Опубликована: Янв. 28, 2025

Язык: Английский

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Ultrafine Particulate Matter Exacerbates the Risk of Delayed Neural Differentiation: Modulation Role of METTL3-Mediated m⁶A Modification

Environmental Science & Technology, Год журнала: 2025, Номер unknown

Опубликована: Фев. 4, 2025

Air pollution, especially from ultrafine particles (PM0.1, ≤0.1 μm), is increasingly recognized for its detrimental effects on health. The influence of PM0.1 neurodevelopmental disorders and underlying mechanisms remain incompletely understood but are significant concern. Through an investigation using mouse embryonic stem cells (mESCs), our study has uncovered disruptions in cell cycle dynamics, reduced neural precursor formation, impaired neurogenesis during mESC differentiation as a result PM0.1-induced toxicity. By employing N6-methyladenosine (m6A) methylated RNA immunoprecipitation sequencing bioinformatics, we identified Zic1 key target developmental disturbances. Our mechanistic findings indicate that enhances m6A methylation by upregulating Mettl3, leading to decreased mRNA stability expression this gene. Furthermore, the efficacy METTL3 inhibitor alleviating nerve impairments emphasizes significance pathway. In addition, source analysis, molecular docking, toxicity analyses show PAHs with higher ring structures combustion sources competitively bind METTL3, potentially exacerbating This not only underscores severe impact neurodevelopment also reveals pivotal role modification mediating these effects, providing valuable insights potential therapeutic targets mitigating PM0.1-related health risks.

Язык: Английский

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Detecting and quantifying PM2.5 and NO2 contributions from train and road traffic in the vicinity of a major railway terminal in Dublin, Ireland

Environmental Pollution, Год журнала: 2024, Номер 361, С. 124903 - 124903

Опубликована: Сен. 6, 2024

Язык: Английский

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Characterization of soot and crystalline atmospheric ultrafine particles

Environmental Pollution, Год журнала: 2024, Номер 364, С. 125314 - 125314

Опубликована: Ноя. 14, 2024

Язык: Английский

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Investigating the spatiotemporal distribution of fine particulate matter sources during persistent cold air pools in Salt Lake County

Atmospheric Environment X, Год журнала: 2024, Номер unknown, С. 100305 - 100305

Опубликована: Ноя. 1, 2024

Язык: Английский

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