Environmental Science & Technology Letters, Год журнала: 2025, Номер unknown
Опубликована: Май 22, 2025
Язык: Английский
Pathogens, Год журнала: 2025, Номер 14(4), С. 301 - 301
Опубликована: Март 21, 2025
Occult hepatitis B infection (OBI) is a serious public health issue. Although number of effective vaccines are available, still poses threat to global health. Patients with OBI usually asymptomatic, but there may be active HBV DNA present in their blood, leading the risk virus transmission during blood transfusions or organ transplantation, constituting hazard recipients and increasing liver cirrhosis cancer. China has progressed development blood-screening technology, significant hidden danger transfusion safety. Therefore, screening transfusion, strengthening monitoring management crucial ensure safety protect
Язык: Английский
Процитировано
0
American Journal of Public Health, Год журнала: 2025, Номер unknown, С. e1 - e5
Опубликована: Май 8, 2025
Measles is a potentially deadly viral infection spread via respiratory droplets from infected individuals. Outbreaks occur when vaccine coverage drops below the threshold of herd, or community, immunity. Using sequencing-based approach, we report prospective (January 7, 2025) detection measles in nucleic acid extracts 2 wastewater treatment plants Houston, Texas, with population more than 218 000 residents. The sequencing data samples contained 53 unique reads mapping to 11 different regions virus genome 99.4% match genotype B3. Importantly, no detections were observed 821 previous same city spanning nearly 3 years monitoring. findings confirmed using droplet digital polymerase chain reaction. A concomitant investigation identified unvaccinated measles-positive travelers living within sewershed as event. This work suggests that analysis valuable comprehensive early warning system facilitates targeted epidemiological investigation. ( Am J Public Health. Published online ahead print May 8, 2025:e1–e5. https://doi.org/10.2105/AJPH.2025.308146 )
Язык: Английский
Процитировано
0
Analytical Chemistry, Год журнала: 2025, Номер unknown
Опубликована: Май 16, 2025
The rapid and multiplexed detection of waterborne viruses is crucial for infection prevention. However, current methods are limited by low-quality probes, instrument dependency, time-consuming procedures. In this study, we developed a high-performance, nanobody pair-based, multichannel homogeneous platform the simultaneous three viruses─SARS-CoV-2, norovirus, influenza A virus─in aquatic environments. To identify robust sensitive multiepitope pairs these viruses, utilized pressure-assisted screening docking techniques. For detection, synthesized distinct SiO2@TQD types with unique excitation wavelengths, each acting as an independent signal label. By integrating antibody arrays labels into unified platform, sensor capable detecting all within 30 min. system demonstrated limits low 1.56 pg/mL SARS-CoV-2 antigen, 0.1 norovirus 0.39 virus surpassing conventional antigen kits sensitivity enhancement 160.26-6.25 × 104-fold. Notable advantages include exceptional specificity, accuracy, stability. This work not only provides transformative solution monitoring pathogens but also establishes versatile framework developing platforms other infectious agents.
Язык: Английский
Процитировано
0
Environmental Science & Technology Letters, Год журнала: 2025, Номер unknown
Опубликована: Май 22, 2025
Язык: Английский
Процитировано
0