ACS Nano, Год журнала: 2025, Номер unknown

Опубликована: Янв. 8, 2025

Reactive oxygen species (ROS) play fundamental roles in various biological and chemical processes nature industries, including cell signaling, disease development aging, immune defenses, environmental remediation, pharmaceutical syntheses, metal corrosion, energy production, etc. As such, their detection is of paramount importance, but accurate identification quantification are technically challenging due to transient with short lifetimes low steady-state concentrations. a highly sensitive selective analytical technique, surface-enhanced Raman spectroscopy (SERS) promising for detecting ROS real-time, enabling situ monitoring ROS-involved electrochemical biochemical events exceptional resolution. This review provides comprehensive analysis the state-of-the-art SERS-based ROS. Herein, principles sensing mechanisms SERS have been critically evaluated, highlighting emerging applications direct indirect systems. The developments reaction schemes probes superoxide (•O2–), hydroxyl radicals (•OH), nitric oxide (•NO), peroxynitrite (ONOO–), hypochlorite (OCl–) presented. Finally, technical challenges future research directions discussed guide design analysis.

Язык: Английский