Beverage Plant Research,
Год журнала:
2023,
Номер
3(1), С. 0 - 0
Опубликована: Янв. 1, 2023
Jinhua
Xiangyuan
(JHXY)
is
a
unique
type
of
Chinese
tea
made
from
roasted
oolong
and
subsequently
fermented
by
Eurotiumcristatum.
In
this
study,
we
investigated
the
potential
benefits
JHXY
on
obese
rats
induced
high-sucrose
high-fat
diet.
infusion
was
administered
orally
at
1.6
g/kg·bw
(HI),
0.8
(MI),
0.4
(LI)
per
day
for10
weeks.
Weight
gain
significantly
suppressed
without
affecting
appetite.
MI
HI
groups,
led
to
significant
reduction
in
triglycerides
(TG),
total
cholesterol
(TC),
low-density
lipoprotein
(LDL-C),
accompanied
an
increase
high-density
(HDL-C)
levels.
A
white
adipose
tissue
(WAT)
index
brown
(BAT)
were
observed.
group,
morphology
hepatocytes
restored.
The
abundance
Bifidobacterium
elevated,
whereas
Desulfovibrio
reduced.
Correlation
analysis
revealed
that
ratio
Ruminococcus
positively
correlated
with
HDL-C;
Christensenellaceae_R7_group
negatively
TC
LDL-C,
while
Lactobacillus
BAT/WAT
ratio.
lipopolysaccharide
biosynthesis
pathway
predicted
be
weakened
(p<0.05);
sulfur
relay
system
attenuated,
bacterial
toxins
augmented
(p<0.05).
Our
research
showed
has
enhance
metabolic
health
maintain
intestinal
homeostasis.
Optimal
dosage
should
focal
point
future
research.
Journal of Functional Foods,
Год журнала:
2023,
Номер
104, С. 105495 - 105495
Опубликована: Март 15, 2023
Intermittent
fasting
(IF)
could
not
work
well
in
females
indicating
that
additional
interventions
might
be
necessary
to
improve
outcomes.
We
here
investigated
whether
Pu-erh
tea
extract
(PTE)
intake
enhance
anti-obesity
effect
of
IF
female
mice
and
explored
the
underlying
mechanisms.
The
combination
PTE
treated
obesity
by
reducing
lipogenesis
enhancing
adipose
thermogenesis.
This
decrease
follicle-stimulating
hormone
(FSH)
reduce
FSH-mediated
UCP1
inhibition
AMPK/PGC1α/UCP1
pathways,
finally
promoting
Based
on
this,
we
speculated
increase
FSH
a
key
reason
for
poor
under
IF.
Besides,
this
modulated
composition
gut
microbes
(restored
Firmicutes/Bacteroidetes
improved
Akkermansia
abundance)
protecting
intestinal
barrier,
further
promoted
production
SCFAs
especially
butyrate
which
induce
thermogenesis
adipose.
Our
results
suggested
an
effective
strategy
combating
females.
Foods,
Год журнала:
2023,
Номер
12(20), С. 3716 - 3716
Опубликована: Окт. 10, 2023
This
study
investigated
the
potential
fat-thermogenic
effects
of
Eurotium
cristatum,
and
elucidated
underlying
mechanisms.
The
12-week
administration
E.
cristatum
in
HFD-fed
obese
mice
reduced
body
weight
improved
glucolipid
metabolism
disorders.
also
efficiently
promoted
thermogenesis
by
increasing
expression
UCP1
PRDM16
both
interscapular
brown
adipose
tissue
(iBAT)
inguinal
white
(iWAT)
mice.
Furthermore,
shaped
gut
microbiome
abundance
Parabacteroides
Akkermansia
muciniphila,
elevated
levels
cecal
short-chain
fatty
acids,
particularly
propionate
acetate.
Of
note,
A.
muciniphila
was
highly
negatively
correlated
with
gain
(r
=
-0.801,
p
<
0.05)
iWAT
index
-0.977,
0.01),
suggesting
that
may
play
an
important
role
thermogenic
mobilization
induced
cristatum.
Continuous
supplementation
suppressed
accumulation,
metabolism,
enhanced
activity
iBAT.
Collectively,
our
results
propose
boosted
acts
as
a
key
microbe
tea-derived
probiotic
cristatum-mediated
anti-obesity
effects.
Advanced Healthcare Materials,
Год журнала:
2024,
Номер
14(4)
Опубликована: Дек. 11, 2024
Roseburia
intestinalis,
enriched
in
the
gut,
is
closely
associated
with
obesity,
intestinal
inflammation,
and
other
diseases.
A
novel
detection
method
for
R.
intestinalis
to
replace
commonly
used
16S
rRNA
sequencing
technique
aim
developed,
thus
enabling
real-time
low-cost
monitoring
of
gut
microbiota.
The
optimal
solution
utilize
rGO-FET
(reduced
graphene
oxide
field-effect
transistor)
functionalized
aptamers.
Due
high
sensitivity
sensors
electronic
changes
system,
it
anticipated
achieve
that
traditional
fluorescence
techniques
cannot
attain.
previous
work
reported
a
nucleic
acid
aptamer
library,
Ri
7_2,
capable
quantitatively
tracking
complex
systems.
However,
due
complexity
library
itself,
large-scale
industrial
synthesis
challenging,
significantly
limiting
its
further
commercial
application
potential.
Therefore,
this
study,
through
Next-Generation
Sequencing
analysis,
four
representative
single
aptamers
from
strategically
selected,
named
A-Rose
1,
2,
3,
4,
confirmed
their
excellent
performance
similar
7_2.
Furthermore,
aptamer-modified
demonstrated
universality
detecting
series
biochemical
analyses,
providing
powerful
diagnostic
tool
clinical
diagnosis
intestinalis.
Beverage Plant Research,
Год журнала:
2023,
Номер
3(1), С. 0 - 0
Опубликована: Янв. 1, 2023
Jinhua
Xiangyuan
(JHXY)
is
a
unique
type
of
Chinese
tea
made
from
roasted
oolong
and
subsequently
fermented
by
Eurotiumcristatum.
In
this
study,
we
investigated
the
potential
benefits
JHXY
on
obese
rats
induced
high-sucrose
high-fat
diet.
infusion
was
administered
orally
at
1.6
g/kg·bw
(HI),
0.8
(MI),
0.4
(LI)
per
day
for10
weeks.
Weight
gain
significantly
suppressed
without
affecting
appetite.
MI
HI
groups,
led
to
significant
reduction
in
triglycerides
(TG),
total
cholesterol
(TC),
low-density
lipoprotein
(LDL-C),
accompanied
an
increase
high-density
(HDL-C)
levels.
A
white
adipose
tissue
(WAT)
index
brown
(BAT)
were
observed.
group,
morphology
hepatocytes
restored.
The
abundance
Bifidobacterium
elevated,
whereas
Desulfovibrio
reduced.
Correlation
analysis
revealed
that
ratio
Ruminococcus
positively
correlated
with
HDL-C;
Christensenellaceae_R7_group
negatively
TC
LDL-C,
while
Lactobacillus
BAT/WAT
ratio.
lipopolysaccharide
biosynthesis
pathway
predicted
be
weakened
(p<0.05);
sulfur
relay
system
attenuated,
bacterial
toxins
augmented
(p<0.05).
Our
research
showed
has
enhance
metabolic
health
maintain
intestinal
homeostasis.
Optimal
dosage
should
focal
point
future
research.
