Glycolipid and Lipopeptide Biosurfactants: Structural Classes and Characterization—Rhamnolipids as a Model DOI

Nadin Darwiche,

Christelle Dufresne,

Agnès Chartier

и другие.

Critical Reviews in Analytical Chemistry, Год журнала: 2024, Номер unknown, С. 1 - 21

Опубликована: Дек. 29, 2024

In recent years, biosurfactants (BS) produced by various bacteria, fungi and yeast strains have attracted much interest because of their unique properties potential applications in many industries ranging from bioremediation to agriculture biomedical cosmetics. Glycolipids are a popular group BS that include rhamnolipids, sophorolipids, mannosylerythritol, trehalose lipids, xylolipids cellobiose lipids. Lipopeptides e.g., surfactins, iturins fengycins major biotechnological antitumor, immunomodulatory, antimicrobial activities effects. This review addresses the structural glycolipids lipopeptides, main domains application as well screening tests production. mostly composed carbohydrate moiety linked ß-hydroxy fatty acid chain with glycosidic bond. The related nature length chain. lipopeptide structure is mainly linear or cyclic peptide acids different lengths. complexity these compounds requires analytical techniques for characterization quantification. As an example, used rhamnolipids presented this review. RLs very promising wide range fields, such cosmetics, food science, pharmaceuticals, environmental remediation.

Язык: Английский

Efficient production of biosurfactant surfactin by a newly isolated Bacillus subtilis (sp.) 50499 strain from oil-contaminated soil DOI
Yulu Du, Yue Wang,

Tianyou Cui

и другие.

Food and Bioproducts Processing, Год журнала: 2023, Номер 142, С. 40 - 49

Опубликована: Сен. 7, 2023

Язык: Английский

Процитировано

11

Generation of Oil Spill Dispersants Composed of Biosurfactants and Chemical Surfactants: Mechanism Exploration through Molecular Dynamics Simulation DOI Creative Commons

Masoumeh Bavadi,

Xing Song, Zhiwen Zhu

и другие.

Journal of environmental chemical engineering, Год журнала: 2024, Номер 12(6), С. 114249 - 114249

Опубликована: Сен. 25, 2024

Язык: Английский

Процитировано

4

Amide Modification of Glycolipid Biosurfactants as Promising Biocompatible Antibacterial Agents DOI

Tianyou Cui,

Lianpeng Ge,

Mengqian Zhao

и другие.

Journal of Agricultural and Food Chemistry, Год журнала: 2024, Номер 72(12), С. 6302 - 6314

Опубликована: Март 14, 2024

Discovering new antibacterial agents is crucial to addressing the increasing risk of bacterial infections induced by antimicrobial resistance in food and agricultural industries. Here, biocompatible acidic-type sophorolipids (ASLs) glucolipids (GLs) prepared via chemical modification natural from fermentation were functionalized amide for use as potential agents. It was found that arginine methyl ester derivative GLs (GLs-d-Arg-OMe) showed excellent activity, killing more than 99.99% Escherichia coli at 200 mg/L. The sterilization dosage against Bacillus subtilis, cereus, Staphylococcus aureus 16–64 mg/L, contrast 32–64 mg/L fungus Candida albicans. In particular, GLs-d-Arg-OMe best biocompatibility with a therapeutic index up 18. shown glycolipids can effectively improve activity while maintaining biocompatibility, which be exploited development novel antibiotics fields.

Язык: Английский

Процитировано

3

Enhancing Aqueous Dispersibility of Uncharged Cellulose Through Biosurfactant Adsorption DOI
Thuy-Linh Phi, Wenyang Xu, Petra Pernot

и другие.

ACS Applied Polymer Materials, Год журнала: 2025, Номер unknown

Опубликована: Май 16, 2025

Язык: Английский

Процитировано

0

Microbial Biosurfactant Hydrogels with Tunable Rheology for Precision 3D Printing of Soft Scaffolds DOI Creative Commons
Elizângela H. Fragal, Alexandre Poirier, Didier Blésès

и другие.

Soft Matter, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Rheology control of biosurfactant-based hydrogels enables precise 3D printing soft scaffolds, offering a sustainable platform for structuring matter in advanced manufacturing and bioengineering.

Язык: Английский

Процитировано

0

Preparation and isolation of hydrophilic mannosylerythritol lipids via chemical modification and stepwise extraction DOI
Fei Yu, Qining Yang,

Tianyou Cui

и другие.

Journal of Surfactants and Detergents, Год журнала: 2024, Номер 27(5), С. 725 - 736

Опубликована: Янв. 28, 2024

Abstract Mannosylerythritol lipids (MELs), a glycolipid biosurfactant, possess great potential in many high‐value‐added fields. However, its water‐insolubility is an important obstacle to wide application, especially home and personal care In this study, new strategy “killing two birds with one stone” based on the chemical modification of natural MELs was developed for preparation hydrophilic MELs. These newly prepared can be efficiently isolated from reacted solution via stepwise extraction methanol/ n ‐hexane system. 88% were recovered MELs, corresponding yield 50%. This mainly attributed esterification fatty acids, representing main relatively‐difficult‐to‐remove impurities fermentative‐produced facilitating separation MEL product extraction. Moreover, these presented comparable surface activities while exhibiting enhanced water solubility biocompatibility. originates generation MEL‐D, resulting deacetylation formation containing just hydrophobic chain (named “MEL‐G”). Hence, present not only beneficial removal (fatty acids) but also improved hydrophilicity.

Язык: Английский

Процитировано

2

Efficient preparation and isolation of sophorolipids with excellent pH-regulated water solubility via environmentally friendly acid-induced chemical modifications DOI
Yang Hu,

Tianyou Cui,

Zhihong Yang

и другие.

Chemical Engineering Journal, Год журнала: 2024, Номер 482, С. 148849 - 148849

Опубликована: Янв. 17, 2024

Язык: Английский

Процитировано

1

Zwitterionic derivatization of rhamnolipids: An efficient and biologically friendly antibacterial agent DOI
Mengqian Zhao, Yu Zheng,

Yefei Wu

и другие.

Chemical Engineering Journal, Год журнала: 2024, Номер unknown, С. 156954 - 156954

Опубликована: Окт. 1, 2024

Язык: Английский

Процитировано

0

Cytotoxicity Evaluation of Microbial Sophorolipids and Glucolipids using Normal Human Dermal Fibroblasts (NHDF) in vitro DOI Creative Commons

Sergio Oliveira Formoso,

Vincent Chaleix, Niki Baccile

и другие.

Toxicology Reports, Год журнала: 2024, Номер 14, С. 101862 - 101862

Опубликована: Дек. 11, 2024

Fibroblasts are considered a key player in the wound healing process. Although this cellular family is constituted by several distinct subtypes, dermal fibroblasts crucial thanks to their ability secrete pro-regenerative growth factors, extracellular matrix (ECM) proteins and immune anti-inflammatory role. Sophorolipids (SL), sophorosides (SS) glucolipids (G), mono-unsaturated (C18:1) or saturated (C18:0), glycolipids derived from microbial fermentation of wild type engineered yeast Starmerella bombicola, constitute novel sustainable class bio-based chemicals with interesting physicochemical characteristics, which allow them form soft diverse structures hydrogels vesicles, micelles complex coacervates potential interest skin regeneration applications. In study, we first tested cytocompatibility broad set molecules on normal human (NHDF). Our results show that, up an upper threshold (0.1 % w/v), (SL-C18:1, G-C18:1, SSbola-C18:1, SL-C18:0 G-C18:0) under study were able sustain cell growth. Furthermore, selected least cytotoxic SL-C18:0) promote measuring gene expression markers (i.e. collagen, elastin, transforming factor β, fibroblast …) using qPCR. Unfortunately, none these modulated involved tissue repair. However, aims encourage community test for high-end biomedical Biosurfactants prepared natural amphiphiles growing importance, goal replacing synthetic surfactants commercial formulations. cytotoxicity profile still poorly known, especially new like single-glucose lipids bolaform sophorolipids. This wants contribute all those applications, could be developed biosurfactants contact (cosmetics, healing). We five structurally-related (C18:1 C18:0 sophorolipids, C18:1 lipids, di-sophoroside) against (NHDF) evaluate metabolic activity toxic among them. To best our knowledge, molecules, general, was never NHDF.

Язык: Английский

Процитировано

0

Glycolipid and Lipopeptide Biosurfactants: Structural Classes and Characterization—Rhamnolipids as a Model DOI

Nadin Darwiche,

Christelle Dufresne,

Agnès Chartier

и другие.

Critical Reviews in Analytical Chemistry, Год журнала: 2024, Номер unknown, С. 1 - 21

Опубликована: Дек. 29, 2024

In recent years, biosurfactants (BS) produced by various bacteria, fungi and yeast strains have attracted much interest because of their unique properties potential applications in many industries ranging from bioremediation to agriculture biomedical cosmetics. Glycolipids are a popular group BS that include rhamnolipids, sophorolipids, mannosylerythritol, trehalose lipids, xylolipids cellobiose lipids. Lipopeptides e.g., surfactins, iturins fengycins major biotechnological antitumor, immunomodulatory, antimicrobial activities effects. This review addresses the structural glycolipids lipopeptides, main domains application as well screening tests production. mostly composed carbohydrate moiety linked ß-hydroxy fatty acid chain with glycosidic bond. The related nature length chain. lipopeptide structure is mainly linear or cyclic peptide acids different lengths. complexity these compounds requires analytical techniques for characterization quantification. As an example, used rhamnolipids presented this review. RLs very promising wide range fields, such cosmetics, food science, pharmaceuticals, environmental remediation.

Язык: Английский

Процитировано

0