Stachyose in combination with L. rhamnosus GG ameliorates acute hypobaric hypoxia-induced intestinal barrier dysfunction through alleviating inflammatory response and oxidative stress
Dingxin Ren,
Mengying Ding,
Junqing Su
и другие.
Free Radical Biology and Medicine,
Год журнала:
2024,
Номер
212, С. 505 - 519
Опубликована: Янв. 9, 2024
Язык: Английский
Hepatoprotective potential of four fruit extracts rich in different structural flavonoids against alcohol-induced liver injury via gut microbiota-liver axis
Food Chemistry,
Год журнала:
2024,
Номер
460, С. 140460 - 140460
Опубликована: Июль 15, 2024
Язык: Английский
Vitamin D3 improves glucose metabolism and attenuates inflammation in prediabetic human and mice
The Journal of Nutritional Biochemistry,
Год журнала:
2024,
Номер
130, С. 109659 - 109659
Опубликована: Апрель 27, 2024
Язык: Английский
Mitigation of high-fat diet-induced hepatic steatosis by thyme (Thymus quinquecostatus Celak) polyphenol-rich extract (TPE): insights into gut microbiota modulation and bile acid metabolism
Food & Function,
Год журнала:
2024,
Номер
15(14), С. 7333 - 7347
Опубликована: Янв. 1, 2024
Thyme
polyphenol-rich
extract
effectively
mitigate
HFD-
induced
NAFLD
by
modulating
the
gut-liver
axis,
specifically
targeting
gut
microbiota
and
bile
acid
metabolism.
Язык: Английский
Brassica rapa L. polysaccharide mitigates hypobaric hypoxia-induced oxidation and intestinal damage via microbiome modulation
Wei Liu,
Zhenjiang Liu,
Xueni Fan
и другие.
npj Science of Food,
Год журнала:
2024,
Номер
8(1)
Опубликована: Дек. 27, 2024
The
high-altitude,
low-pressure,
and
hypoxia
environment
poses
a
significant
threat
to
human
health,
particularly
causing
intestinal
damage
disrupting
gut
microbiota.
This
study
investigates
the
protective
effects
of
Brassica
rapa
L.
crude
polysaccharides
(BRP)
on
in
mice
exposed
hypobaric
hypoxic
conditions.
Results
showed
that
oxidative
stress
inflammation
levels
were
elevated
group,
while
BRP
intervention
significantly
increased
antioxidant
enzyme
activities
(SOD,
GSH-Px,
T-AOC)
reduced
inflammatory
markers
(IL-6,
IL-1β,
TNF-α).
also
restored
barrier
function
by
enhancing
claudin-1,
occludin,
ZO-1
expression.
Notably
Chromatographic
metagenomic
analyses
revealed
enriched
butyrate
levels,
promoted
beneficial
bacteria
like
Akkermansia
muciniphila
Leuconostoc
lactis,
upregulated
L-arginine
biosynthesis
II
L-methionine
III
pathways
enhance
activity.
Fecal
microbiota
transfer
experiments
confirmed
role
mediating
BRP's
effects,
providing
valuable
insights
into
prebiotic-based
therapeutic
strategies
for
hypoxia-induced
damage.
Язык: Английский
Citrus endogenous components as prebiotics: Advances in extraction, digestion, mechanisms, and delivery
Food Research International,
Год журнала:
2025,
Номер
208, С. 116141 - 116141
Опубликована: Март 10, 2025
Язык: Английский
Unveiling the potentials and action mechanisms of Citri reticulatae Pericarpium as an anti‐inflammatory food
Food Frontiers,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 13, 2024
Abstract
Modern
lifestyle
has
led
human
body
under
a
frequent
exposure
of
chronic
inflammation.
Intriguingly,
extensive
studies
have
indicated
that
Citri
reticulatae
Pericarpium
(CRP),
the
dried
peel
Citrus
reticulata
Blanco
and
its
cultivated
varieties,
immense
potential
as
an
anti‐inflammatory
food.
Therefore,
present
review
aims
to
summarize
advances
in
utilizing
CRP
for
prevention
controlling
inflammation
various
pathological
conditions.
In
particular,
this
provides
comprehensive
overview
bioactive
compounds
CRP,
with
specific
focus
on
polymethoxyflavones
their
transformations
during
aging
process.
Moreover,
underlying
mechanism
responsible
effects
primarily
involves
inhibition
inflammatory
factors
through
signaling
pathways,
such
mitogen‐activated
protein
kinases
nuclear
factor‐erythroid
2‐related
factor
2–antioxidant
pathways.
The
interaction
gut
microbiota
also
contributes
CRP.
summary,
offers
valuable
insights
into
health
benefits
constituents,
laying
solid
foundation
further
development
foods.
Язык: Английский
Brassica rapa L. crude polysaccharide ameliorates hypobaric and hypoxia induced oxidative stress and intestinal damage by modulating gut microbiome
Wei Liu,
Zhenjiang Liu,
Xueni Fan
и другие.
Research Square (Research Square),
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 26, 2024
Abstract
The
high-altitude,
low-pressure,
and
hypoxia
environment
poses
a
significant
threat
to
human
health,
particularly
causing
intestinal
damage
disrupting
gut
microbiota.
This
study
investigates
the
protective
effects
of
Brassica
rapa
L.
crude
polysaccharides
(BRP)
on
in
mice
exposed
hypobaric
hypoxic
conditions.
Results
showed
that
oxidative
stress
inflammation
levels
were
elevated
group,
while
BRP
intervention
significantly
increased
antioxidant
enzyme
activities
(SOD,
GSH-Px,
T-AOC)
reduced
inflammatory
markers
(IL-6,
IL-1β,
TNF-α).
also
restored
barrier
function
by
enhancing
claudin-1,
occludin,
ZO-1
expression.
Notably
Chromatographic
metagenomic
analyses
revealed
enriched
butyrate
levels,
promoted
beneficial
bacteria
like
Akkermansia
muciniphila
Leuconostoc
lactis,
upregulated
L-arginine
biosynthesis
II
L-methionine
III
pathways
enhance
activity.
Fecal
microbiota
transfer
experiments
confirmed
role
mediating
BRP's
effects,
providing
valuable
insights
into
prebiotic-based
therapeutic
strategies
for
hypoxia-induced
damage.
Язык: Английский
Phytochemicals as alternatives of antibiotics in modulation of gut microbiota
Studies in natural products chemistry,
Год журнала:
2024,
Номер
unknown, С. 341 - 383
Опубликована: Янв. 1, 2024
Язык: Английский
Flavonoids from Ougan (Citrus suavissima Hort. ex Tanaka) peel exert hypoglycemic potency through inhibiting insulin resistance in HepG2 cells and regulating gut microbiota in diabetic mice
Journal of Functional Foods,
Год журнала:
2024,
Номер
123, С. 106596 - 106596
Опубликована: Ноя. 27, 2024
Язык: Английский