Molecules,
Год журнала:
2023,
Номер
28(19), С. 6965 - 6965
Опубликована: Окт. 7, 2023
3-chloro-4-hydroxyphenylacetic
acid
(CHPAA)
is
a
fungal
metabolite.
It
small
molecule
that
useful
in
crystal
engineering
studies
due
to
the
functional
groups
present.
Six
amines
were
selected
form
salts
with
CHPAA.
Linear
derivatives
included
diethylamine
(DEA)
and
di-N-butylamine
(DBM).
The
aromatic
compounds
chosen
2-aminopyridine
(A2MP),
2-amino-4-methylpyridine
(A24MP),
2-amino-6-methylpyridine
(A26MP)
4-dimethylaminopyridine
(DMAP).
characterised
using
single-crystal
X-ray
diffraction,
thermal
analysis,
FTIR
spectroscopy
Hirshfeld
surface
analysis.
For
all
structures,
N-H···O
C-H···Cl
contacts
O-H···O
found
structures
except
for
(CHPAA2-)2DEA+,
which
was
also
only
structure
displayed
Cl···Cl
contact.
Furthermore,
C-H···O
(CHPAA-)(DBM+).
stability
trend
showed
DBM
salt
more
stable
than
DEA
salt.
co-formers,
following:
CHPAA-(DMAP+)
>
(CHPAA-)(A2MP+)>2CHPAA-2A26MP+>(CHPAA-)(A24MP+).
Crystal Growth & Design,
Год журнала:
2024,
Номер
24(4), С. 1746 - 1765
Опубликована: Фев. 9, 2024
Controlling
the
supramolecular
synthon
outcome
in
systems
with
different
functionalities
has
been
a
key
factor
for
design
of
materials,
which
also
affected
their
physicochemical
properties.
In
this
contribution,
we
have
analyzed
structural
landscape
α-acetamidocinnamic
acid
(HACA)
aiming
to
find
its
from
competitivity
between
acidic
and
amidic
groups.
We
prepared
four
multicomponent
forms
including
one
dihydrate
(HACA·2H2O)
three
cocrystals
bearing
bipyridine
coformers
formulas
(HACA)2(1,2-bpe)
(1),
(HACA)2(4,4′-azpy)
(2),
(HACA)2(4,4′-bipy)3
(3)
(1,2-bpe
=
1,2-bis(4-pyridyl)ethylene;
4,4′-azpy
4,4′-azopyridine;
4,4′-bipy
4,4′-bipyridine).
First,
applied
virtual
screening
approach
assess
feasibility
cocrystal
formation.
Then,
synthesized
cocrystals,
via
liquid-assisted
grinding
(LAG)
(1
2)
or
solvothermal
techniques,
single
crystals
HACA,
were
obtained
showing
synthons
crystal
packings.
Besides,
Cambridge
Structural
Database
(CSD)
search
presenting
bipyridine-type
molecules
amide
was
performed,
observed
occurrences
as
well
possibility
modification
by
tuning
H-donor/H-acceptor
propensity
groups
shown.
Finally,
measured
thermal
photophysical
properties,
correlated
features.
ACS Applied Nano Materials,
Год журнала:
2024,
Номер
7(12), С. 14516 - 14525
Опубликована: Июнь 19, 2024
Traditional
pesticide
emulsion
formulation
may
exert
deleterious
effects
on
the
environment
and
even
induce
stress
nontarget
crops
in
vicinity.
In
this
study,
γ-cyclodextrin
(γ-CD)-encapsulated
azobenzene
derivative
nanovesicles
were
synthesized
loaded
with
pendimethalin
to
obtain
pendimethalin-loaded
γ-CD/azobenzene
nanovesicles.
Upon
exposure
ultraviolet
irradiation
or
sunlight,
derivatives
are
converted
from
trans-
cis-
configuration,
leading
dissociation
of
ternary
host–guest
complexes,
resulting
vesicle
rupture
subsequent
release
pendimethalin.
Further
investigations
conducted
According
characteristics
herbicides,
rate
under
light
(365
nm)
sunlight
conditions
reached
88.3
±
3%,
which
was
4.3
times
higher
than
that
dark
conditions,
demonstrating
excellent
photocontrolled
behavior.
Pot
experiments
showed
herbicidal
activity
against
Portulaca
oleracea
(L.)
Echinochloa
crusgalli
Beauv.
at
recommended
dose
comparable
technical
illuminated
conditions.
Furthermore,
genotoxicity
reveal
a
notable
increase
mitotic
index
onion
root
tip
cells
treated
nanovesicles,
indicating
it
had
minimal
inhibitory
effect
cell
metabolism
lower
technical.
Pendimethalin-loaded
exhibited
favorable
stability
photoresponsive
performance.
These
findings
promising
avenue
for
responsive
material
design
modulation
using
such
nanovesicle
systems,
providing
insights
into
their
potential
applications
targeted
delivery
systems.
