Molecules,
Год журнала:
2024,
Номер
29(24), С. 5971 - 5971
Опубликована: Дек. 18, 2024
Hyaluronic
acid
(HA)
is
an
acidic
mucopolysaccharide
of
animal
origin
composed
repeating
disaccharide
units
N-acetylglucosamine
and
glucuronic
acid.
Due
to
its
excellent
biocompatibility,
biodegradability,
selective
affinity
for
CD44
receptors
on
cell
surfaces,
HA
widely
employed
as
a
drug
carrier.
In
our
study,
we
aimed
target
subcellular
bacteria
by
grafting
cystamine
onto
scaffolds
through
amide
reaction,
producing
linker
responsive
H2S
pH
changes.
Subsequently,
hydrophobic
dodecylamine
was
attached
HA,
forming
amphiphilic
molecules.
These
entities
can
self-assemble
into
nanomicelles
in
aqueous
solution,
thereby
encapsulating
the
antibacterial
agent
triclosan
(TCS).
The
resulting
HA-based
system
(HASS-TCS)
be
internalized
via
CD44-mediated
endocytosis,
releasing
substantial
amounts
streptomycin
TCS
H2S-rich
environments.
Additionally,
HASS-TCS
has
demonstrated
effectiveness
eradicating
biofilms
addressing
intracellular
infections
caused
Salmonella.
This
study
underscores
novel
pH-sensitive
hyaluronic
acid-based
delivery
with
significant
potential
effective
treatment
infections.
Sensors,
Год журнала:
2024,
Номер
24(16), С. 5143 - 5143
Опубликована: Авг. 8, 2024
This
comprehensive
review
delves
into
the
forefront
of
biosensor
technologies
and
their
critical
roles
in
disease
biomarker
detection
therapeutic
drug
monitoring.
It
provides
an
in-depth
analysis
various
types
applications,
including
enzymatic
sensors,
immunosensors,
DNA
elucidating
mechanisms
specific
healthcare
applications.
The
highlights
recent
innovations
such
as
integrating
nanotechnology,
developing
wearable
devices,
trends
miniaturisation,
showcasing
transformative
potential
healthcare.
In
addition,
it
addresses
significant
sensitivity,
specificity,
reproducibility,
data
security
challenges,
proposing
strategic
solutions
to
overcome
these
obstacles.
is
envisaged
that
will
inform
decision-making,
drive
technological
innovation,
enhance
global
outcomes
by
synthesising
multidisciplinary
insights.
Applied Surface Science Advances,
Год журнала:
2023,
Номер
18, С. 100491 - 100491
Опубликована: Ноя. 18, 2023
Nanostructured
NdMnO3:rGO
samples
were
synthesized
via
the
ultrasonicated
sol-gel
method
by
adding
rGO
concentrations
(0–20
wt.%).
The
formation
of
a
pure
orthorhombic
structure
having
"pnma"
space
group
confirmed
absence
any
secondary
phase
nanocomposites.
bandgap
was
determined
from
Tauc's
plot
to
be
2.20–1.74
eV
concerning
concentrations.
highest
photocatalytic
degradation
rate
achieved
0.530
for
particular
concentration
20
wt.%.
enhanced
activity
nanocomposite
is
attributed
higher
separation
efficiency
photo-induced
electron-hole
pairs
and
extensive
surface
contact
between
NdMnO3.
These
findings
convincingly
show
that
photocatalysts
possess
great
potential
UV–visible
light-driven
photodegradation
MB.
Materials Science and Engineering R Reports,
Год журнала:
2024,
Номер
160, С. 100826 - 100826
Опубликована: Июль 17, 2024
Ultrafast
UV
photodetectors
(UV
PDs)
are
crucial
components
in
modern
optoelectronics
because
conventional
detectors
have
reached
a
bottleneck
with
low
integration,
functionalities,
and
efficiency.
Core-shell
metal
oxide
nanobrushes
(MOx
NBs)-based
PDs
enhanced
the
absorption,
tunable
performance,
good
compatibility
for
diversified
applications,
including
imaging,
self-powered
systems,
remote
communications,
security,
wearable
electronics.
developed
complex
hierarchical
or
heterostructured
configurations
that
encapsulate
1D
MOx
nanowires
on
nanostructures
(NSs)
to
transport
high
charge
carrier
mobility
efficiency
by
reducing
scattering
recombination
rates.
This
review
presents
thorough
development
of
core-shell
microstructure
enhancement
detection
response
stability
controlled
parameters
multifunctional
applications.
Significant
roles
NBs-based
exploring
various
growth
techniques
photodetection
mechanisms
their
challenges,
limitations,
prospects,
providing
valuable
insights
propelling
progression
photodetector
technology
this
comprehensive
discussed
meticulously.
The
novelty
lies
distinctive
brush-like
morphology
aspect,
properties,
improved
performance
compared
other
NSs,
rapid
sensitive
(
̴µs-ms)
under
light
illumination.
diverse
photoresponse
applications
incorporating
NBs
carefully
summarized,
which
will
set
roadmap
future
technology.
This
research
work
aimed
to
isolate
and
culture
the
bacterium
Bacillus
paramycoides
for
biogenic
fabrication
of
zinc
oxide
nanoparticles,
specifically
ZnO
ZnO-ME
nanoparticles
(nanoparticles
fabricated
from
bacterial
extracts
only
–
ZnO,
cell
mass
including
extract
ZnO-ME).
SEM
investigation
revealed
spherical-shaped
NPs
with
22.33
39
nm
in
size
ZnO-ME,
respectively.
The
Brunauer,
Emmett,
Teller
(BET)
studies
mesoporous
structure
pore
diameters
13.839
13.88
surface
area
7.617
33.635
m2/gm
Various
parameters
adsorption
sulfur
black
dye
onto
both
were
screened
optimized
using
Plackett–Burman
Design
(PBD),
Full
Factorial
(FFD)
Central
Composite
(CCD).
results
optimization
modeling
study
that
FFD
yielded
most
predictable
best-fitting
among
all
models
studied,
R2
values
0.998
0.993
ZnO-ME.
Notably,
exhibited
a
greater
removal
efficiency
80%
than
i.e.,
71%,
it
may
be
due
presence
amorphous
carbon
on
Among
various
isothermal
models,
Freundlich
model
displayed
strongest
correlation
data,
confirming
multilayer
supporting
physisorption.
Therefore,
have
been
proven
as
potential
tools
mitigating
environmental
impacts
associated
dye-containing
wastewater.
Biosensors,
Год журнала:
2023,
Номер
13(9), С. 850 - 850
Опубликована: Авг. 26, 2023
The
abuse
of
antibiotics
has
caused
a
serious
threat
to
human
life
and
health.
It
is
urgent
develop
sensors
that
can
detect
multiple
quickly
efficiently.
Biosensors
are
widely
used
in
the
field
antibiotic
detection
because
their
high
specificity.
Advanced
artificial
intelligence/machine
learning
algorithms
have
allowed
for
remarkable
achievements
image
analysis
face
recognition,
but
not
yet
been
biosensors.
Herein,
this
paper
reviews
biosensors
simultaneous
based
on
different
mechanisms
biorecognition
elements
recent
years,
compares
analyzes
characteristics
specific
applications.
In
particular,
review
summarizes
some
AI/ML
with
excellent
performance
detection,
which
provide
platform
intelligence
terminal
apps
portability.
Furthermore,
gives
short
antibiotics.
