Harnessing Microalgae as Sustainable Cell Factories for Polyamine-Based Nanosilica for Biomedical Applications
Molecules,
Год журнала:
2025,
Номер
30(8), С. 1666 - 1666
Опубликована: Апрель 8, 2025
Microalgae
are
microscopic
unicellular
organisms
that
inhabit
marine,
freshwater,
and
moist
terrestrial
ecosystems.
The
vast
number
diversity
of
microalgal
species
provide
a
significant
reservoir
biologically
active
compounds,
highly
promising
for
biomedical
applications.
Diatoms
eukaryotic
algae
belonging
to
the
class
Bacillariophyceae.
They
possess
intricately
structured
silica-based
cell
walls,
which
contain
long-chain
polyamines
play
important
roles
in
formation
silica.
Long-chain
uncommon
found
only
produce
biosilica.
Diatomite,
is
marine
sediment
remains
silica
skeleton
diatoms,
could
be
an
abundant
source
biogenic
can
easily
converted
particles.
This
concise
review
focuses
on
biofabrication
polyamine-based
nanosilica
from
diatoms
highlights
possibility
utilizing
diatom
biosilica
as
nanocarrier
drug
siRNA
delivery,
bioimaging,
bone
tissue
engineering.
challenges
may
affect
production,
including
environmental
stresses
climate
change,
discussed
together
with
prospect
increasing
diatom-based
production
desired
nanostructures
via
genetic
manipulation.
Язык: Английский
Metabolomics of rapeseed (Brassica napus var. oleifera Del.) sprouts obtained with or without salinity from progeny seeds of mother plants grown in presence or absence of salinity
Journal of Agriculture and Food Research,
Год журнала:
2025,
Номер
unknown, С. 101649 - 101649
Опубликована: Янв. 1, 2025
Язык: Английский
Enrichment of the nutritional value of pea flour milling fractions through fermentation
Food Chemistry,
Год журнала:
2025,
Номер
476, С. 143303 - 143303
Опубликована: Фев. 13, 2025
In
this
work,
pea
flour
and
two
milling
fractions
obtained
by
industrial-scale
air
classification
were
characterized
fermented
Lactiplantibacillus
plantarum
to
increase
their
nutritional
value.
Scanning
electron
microscopy
chemical
analysis
revealed
major
differences
in
the
morphology
composition
of
flours.
Protein-rich
(43.7
%)
fraction
exhibits
a
few-fold
higher
mineral,
spermidine
(290
μg/g),
but
also
phytate
(20.4
mg/g)
content
compared
starch-rich
fraction.
Flour
type
inoculum
majorly
influenced
product.
spontaneously
flours,
biogenic
amines
accumulated
up
6.6
mg/g,
which
was
main
drawback
besides
large
variations
between
batches,
as
confirmed
metagenomic
analysis.
Higher
contents
lactic
acid,
free
amino
groups
formed
proteolysis
gamma-aminobutyric
acid
determined
inoculated
fermentations
protein
rich
fraction,
whereas
relative
bioavailability
minerals
found
reduced
42
%.
Язык: Английский
Identification of Polyamines in Human Milk, Formula Milk, and Other Dairy Products: a Special Method Based on Precolumn Derivatization, Double-Florisil Purification, and Gas Chromatography–Triple Quadrupole Mass Spectrometry
Journal of Agricultural and Food Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 25, 2025
Polyamines
in
human
milk
are
essential
for
the
rapid
growth
and
development
of
neonates
infants.
However,
concentrations
polyamines
have
not
been
well
characterized
special
methods
detecting
milk,
formula
or
other
dairy
products
remain
largely
unavailable
to
date.
In
this
study,
an
accurate
sensitive
method
based
on
trifluoroacetic
acid
anhydride
(TFAA)
derivatization,
double
solid-phase
extraction
(SPE)
purification,
gas
chromatography-triple
quadrupole
mass
spectrometry
(GC-QqQ
MS)
was
established
evaluation
products.
High
coefficients
determination
internal
calibration
curves
were
obtained
(R2
>
0.99).
Low
limits
detection
(5.0,
1.0,
0.5
nmol/dL)
quantification
(10.0,
3.0,
1.0
putrescine,
spermidine,
spermine,
respectively,
also
achieved.
The
precision
(expressed
as
relative
standard
deviation,
RSD
<
9.0%)
recovery
rates
(78.3-108.4%)
satisfactory.
Spermidine
spermine
found
significantly
higher
than
those
commercial
cow's
milk.
difference
polyamine
content
infant
should
be
paid
attention
to,
particularly
when
is
used
a
complete
replacement
Язык: Английский