Effects of Bacillus subtilis Natto NB205 and Its Mutant NBMK308 on Egg Quality in Aging Laying Hens DOI Creative Commons
Chaoyong Liao, Jian Cui, Jiaqi Lei

и другие.

Life, Год журнала: 2023, Номер 13(5), С. 1109 - 1109

Опубликована: Апрель 29, 2023

In aging laying hens, reproductive changes reduce egg quality.

Язык: Английский

CRISPR-Cas9-based genome-editing technologies in engineering bacteria for the production of plant-derived terpenoids DOI Creative Commons
Xin Sun,

Haobin Zhang,

Yuping Jia

и другие.

Engineering Microbiology, Год журнала: 2024, Номер 4(3), С. 100154 - 100154

Опубликована: Май 29, 2024

Terpenoids are widely used as medicines, flavors, and biofuels. However, the use of these natural products is largely restricted by their low abundance in native plants. Fortunately, heterologous biosynthesis terpenoids microorganisms offers an alternative sustainable approach for efficient production. Various genome-editing technologies have been developed microbial strain construction. Clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR associated protein 9 (Cas9) most commonly system owing to its outstanding efficiency convenience genome editing. In this review, basic principles CRISPR-Cas9 systems briefly introduced applications engineering bacteria production plant-derived summarized. The aim review provide overview current developments CRISPR-Cas9-based bacterial engineering, concluding with perspectives on challenges opportunities technologies.

Язык: Английский

Процитировано

5

Improving Bacillus subtilis as Biological Chassis Performance by the CRISPR Genetic Toolkit DOI
Xingzhong Cao, Xiaojuan Wang, Ruirui Chen

и другие.

ACS Synthetic Biology, Год журнала: 2025, Номер unknown

Опубликована: Март 4, 2025

Bacillus subtilis is the model Gram-positive and industrial chassis bacterium; it has blossomed as a robust promising host for enzyme, biochemical, or bioflocculant production. However, synthetic biology metabolic engineering technologies of B. have lagged behind most widely used Saccharomyces cerevisiae Escherichia coli. CRISPR (an acronym clustered regularly interspaced short palindromic repeats) enables efficient, site-specific, programmable DNA cleavage, which revolutionized manner genome editing. In 2016, technology was first introduced into been intensely upgraded since then. this Review, we discuss recently developed key additions to toolkit design in with gene editing, transcriptional regulation, enzyme modulation. Second, advances efficient biochemicals proteins are discussed. Finally, conclude perspectives on challenges opportunities CRISPR-based biotechnology subtilis, wishing that can be comparable traditional microorganisms such E. coli S. someday soon.

Язык: Английский

Процитировано

0

Biosynthesis and therapeutic applications of MK-7: A comprehensive review DOI Creative Commons
Manoj Kumar Khanna,

C. Subathra Devi

Cogent Food & Agriculture, Год журнала: 2025, Номер 11(1)

Опубликована: Май 27, 2025

Язык: Английский

Процитировано

0

Effects of Bacillus subtilis Natto NB205 and Its Mutant NBMK308 on Egg Quality in Aging Laying Hens DOI Creative Commons
Chaoyong Liao, Jian Cui, Jiaqi Lei

и другие.

Life, Год журнала: 2023, Номер 13(5), С. 1109 - 1109

Опубликована: Апрель 29, 2023

In aging laying hens, reproductive changes reduce egg quality.

Язык: Английский

Процитировано

4