Foods,
Год журнала:
2025,
Номер
14(11), С. 1956 - 1956
Опубликована: Май 30, 2025
To
enhance
the
low-efficiency
but
potentially
health
and
environmentally
friendly
aqueous
decaffeination
process,
ultrasound-assisted
extraction
(UAAE)
has
recently
been
proposed.
A
novel
concept
of
intermittent
water
change
to
further
UAAE
also
mentioned,
not
yet
studied
in
detail.
For
this
reason,
a
mathematical
model
that
can
be
used
predict
concentration
evolutions
caffeine
during
conventional
(CAE)
whole
green
robusta
coffee
beans
is
herein
The
consists
terms
representing
transient
intra-bean
diffusion
as
well
molar
fluxes
on
bean
surface.
After
validation,
was
investigate
effects
temperature,
bean-to-water
mass
ratio
frequency
evolutions.
Simulation
results
show
exhibits
around
10%
higher
removal
rates
than
CAE
at
all
investigated
conditions.
Extraction
temperature
70
°C,
1:3,
every
1
h
interval
are
noted
most
appropriate
conditions
for
UAAE.
required
durations
under
these
13
24
meet
US
European
Union
standards,
respectively.
Evidence-based Complementary and Alternative Medicine,
Год журнала:
2022,
Номер
2022, С. 1 - 21
Опубликована: Июль 4, 2022
Cardiovascular
diseases
(CVDs)
are
the
world's
leading
killers,
accounting
for
30%
deaths.
According
to
WHO
report,
CVDs
kill
17.9
million
people
per
year,
and
there
will
be
22.2
deaths
from
CVD
in
2030.
The
death
rates
rise
as
get
older.
Regarding
gender,
rate
of
women
by
(51%)
is
higher
than
that
men
(42%).
To
decrease
prevent
CVD,
most
rely
on
traditional
medicine
originating
plant
(phytochemicals)
addition
or
preference
commercially
available
drugs
recover
their
illness.
therapy
efficacy
92
plants,
including
15
terrestrial
examined.
Some
medicinal
plants
well
known
treat
are,
Nutrients,
Год журнала:
2018,
Номер
10(10), С. 1386 - 1386
Опубликована: Сен. 30, 2018
Cognitive
and
mood
benefits
of
coffee
are
often
attributed
to
caffeine.
However,
emerging
evidence
indicates
behavioural
effects
non-caffeine
components
within
coffee,
suggesting
the
potential
for
direct
or
synergistic
these
compounds
when
consumed
with
caffeine
in
regular
brewed
coffee.
The
current
randomised,
placebo-controlled,
double-blind,
counterbalanced-crossover
study
compared
decaffeinated
placebo
on
measures
cognition
mood.
Age
sex
were
explored
by
comparing
responses
older
(61–80
years,
N
=
30)
young
(20–34
29)
males
females.
Computerised
episodic
memory,
working
attention,
subjective
state
completed
at
baseline
30
min
post-drink.
Regular
produced
expected
decreased
reaction
time
increased
alertness
placebo.
When
digit
vigilance
accuracy
tiredness
headache
ratings
observed.
Decaffeinated
also
Higher
jittery
following
females
represented
only
interaction
age
treatment.
These
findings
suggest
activity
beyond
its
content,
raising
issues
use
as
a
highlighting
need
further
research
into
psychoactive
effects.
Nutrition & Metabolism,
Год журнала:
2019,
Номер
16(1)
Опубликована: Май 3, 2019
This
study
aimed
to
assess
the
potential
effects
of
long-term
intake
caffeine
and
habitual
consumption
coffee
tea
on
occurrence
cardio-renal
events
among
an
Iranian
population
with
low
high
consumption.
Adult
participants
Tehran
Lipid
Glucose
Study
(2006–2008
2012–2014)
who
met
inclusion
criteria,
were
recruited.
Habitual
dietary
intakes
assessed
using
a
validated
food
frequency
questionnaire.
Demographics,
anthropometrics,
blood
pressure,
biochemical
variables
evaluated
at
baseline
during
follow-up
examinations.
Multivariate
Cox
proportional
hazard
logistic
regression
models
adjusted
for
confounders
used
estimate
risk
cardiovascular
disease
(CVD),
hypertension
(HTN)
chronic
kidney
(CKD).
During
median
6
years
follow-up,
incidence
rate
CVD
outcomes,
HTN,
CKD
3.3%,
15.5%,
17.9%,
respectively.
The
was
increased
more
than
two-fold
in
highest
tertile
(HR
=
2.44,
95%
confidence
interval,
CI
1.40–4.27;
P
trend
0.001),
2.22,
1.23–4.01;
0.005).
A
42%
lower
observed
drinkers,
compared
non-drinkers
0.58,
0.36–0.93;
0.023).
No
significant
association
between
tea,
or
HTN
CKD.
Findings
our
support
previous
data
regarding
protective
CVD.
Contrary
studies,
we
found
that
higher
caffeine,
mainly
originated
from
population,
may
increase
events.
It
be
related
type
its
preparation
methods,
additives
artificial
colors
consumed
Iran,
sweets
sugar
mostly
accompanied
by
tea.
Also,
genetic
variants
liver
enzymes
modify
sources
Further
prospective
studies
incorporation
different
habits
backgrounds
are
needed
clarify
contradictions.
Critical Reviews in Food Science and Nutrition,
Год журнала:
2021,
Номер
62(22), С. 6132 - 6152
Опубликована: Март 11, 2021
To
date,
there
exists
a
debate
on
the
effect
of
milk
added
to
coffee
infusions/beverages
concerning
nutritional
quality
and
functional
properties
its
phenolic
compounds.
Yet,
full
beverage
without
significant
negative
impact
sensorial
profile
are
highly
desired
by
consumers.
Negative/masking,
positive,
neutral
effects
antioxidant
activity
bioavailability
phenolics
(particularly,
chlorogenic
acids)
have
been
reported.
Some
potential
factors
including
type
amount
added,
beverage,
composition
both
(protein
fat)
(phenolic
compounds),
preparation
method,
assays
used
measure
properties,
sampling
size
may
account
for
various
reported
findings.
Interactions
between
compounds
in
proteins
could
as
main
responsible
aspect
masking/negative
bioaccessibility/bioavailability
bioactives.
However,
considering
interactions
components
phenolics,
which
result
loss
their
functionality,
role
fat
globules
globule
membrane
can
also
be
crucial,
but
this
has
not
addressed
literature
so
far.HighlightsIn
most
cases,
is
beverages
several
ways.Effect
nutritional/functional
controversial.Enough
evidence
suggests
addition
coffee.Interactions
aspect.The
crucial.
Ochsner Journal,
Год журнала:
2023,
Номер
23(2), С. 152 - 158
Опубликована: Янв. 1, 2023
Background:
Coffee
is
a
widely
available
beverage
that
enjoyed
by
individuals
of
many
cultures.
The
publication
new
studies
prompts
review
the
clinical
updates
regarding
association
between
coffee
consumption
and
cardiovascular
disease.
Methods:
We
present
narrative
literature
related
to
Results:
Recent
(2000-2021)
have
shown
regular
associated
with
decreased
risk
developing
hypertension,
heart
failure,
atrial
fibrillation.
However,
results
are
inconsistent
regard
coronary
Most
show
J-shaped
association,
wherein
moderate
resulted
in
disease
heavy
increased
risk.
In
addition,
boiled
or
unfiltered
more
atherogenic
than
filtered
because
its
rich
diterpene
content
inhibits
bile
acid
synthesis
ultimately
affects
lipid
metabolism.
On
other
hand,
coffee,
which
essentially
devoid
aforementioned
compounds,
exerts
antiatherogenic
properties
increasing
high-density
lipoprotein–mediated
cholesterol
efflux
from
macrophages
through
influence
plasma
phenolic
acid.
As
such,
levels
principally
influenced
manner
preparation
(boiled
vs
filtered).
Conclusion:
Our
findings
suggest
leads
decrease
all-cause
cardiovascular-related
mortality,
cholesterol,
no
conclusive
relationship
has
been
consistently
identified.
Nutrients,
Год журнала:
2023,
Номер
15(13), С. 3060 - 3060
Опубликована: Июль 7, 2023
Objectives:
The
association
between
coffee
intake
and
hypertension
(HTN)
risk
is
controversial.
Therefore,
this
systematic
review
meta-analysis
aimed
at
summarizing
the
current
evidence
on
of
with
in
observational
studies.
Methods:
PubMed/Medline
Web
Science
were
searched
for
studies
up
to
February
2023.
Observational
which
assessed
HTN
highest
category
consumption
comparison
lowest
included
(registration
number:
CRD42022371494).
pooled
effect
was
evaluated
using
a
random-effects
model.
Results:
Twenty-five
i.e.,
thirteen
cross-sectional
twelve
cohorts
identified
be
eligible.
Combining
13
extracted
sizes
from
cohort
showed
that
higher
associated
7%
reduction
(95%
CI:
0.88,
0.97;
I2:
22.3%),
whereas
combining
16
illustrated
greater
(RR
=
0.79,
95%
0.72,
0.87;
I2
63.2%).
These
results
varied
by
characteristics,
such
as
region
study,
participants’
sex,
study
quality,
sample
size.
Conclusions:
An
inverse
found
both
However,
dependent
characteristics.
Further
considering
factors
are
required
confirm
study.
