The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
89(11), С. 8035 - 8040
Опубликована: Май 28, 2024
Mild,
metal-free,
and
operationally
simple
three-component
coupling
reactions
involving
arynes,
phosphites,
acrylates
have
been
achieved.
The
reaction
proceeded
well
with
α-
or
β-substituted
acrylates.
Additionally,
various
functional
groups
were
tolerated
under
these
conditions,
resulting
in
diverse
The Journal of Organic Chemistry,
Год журнала:
2023,
Номер
88(13), С. 8465 - 8479
Опубликована: Май 24, 2023
A
mild,
efficient,
and
transition-metal-free
three-component
coupling
reaction
involving
arynes,
phosphites,
aldehydes
was
established
to
afford
3-mono-substituted
benzoxaphosphole
1-oxides.
range
of
1-oxides
obtained
from
both
aryl-
aliphatic-substituted
in
moderate
good
yields.
Moreover,
the
synthetic
utility
demonstrated
by
a
Gram-scale
transformation
products
into
various
P-containing
bicycles.
European Journal of Organic Chemistry,
Год журнала:
2023,
Номер
26(29)
Опубликована: Июль 14, 2023
Abstract
C2‐functionalized
pyrimidine
derivative
is
a
family
of
important
nitrogen
heterocyclic
compounds
due
to
their
unique
structure
and
multiple
reaction
sites.
In
this
work,
novel
method
for
the
synthesis
derivatives
through
phenylalkynes
disulfides
under
ambient
conditions
proposed.
The
can
be
triggered
by
adding
catalytic
amounts
cesium
fluoride,
which
characterized
free‐catalyst
special
activator.
Importantly,
has
good
compatibility
with
substrates
substituted
electron‐donating
electron‐withdrawing
groups
at
C4.
Density
functional
theory
(DFT)
calculations
also
indicates
that
production
more
favourable.
Asian Journal of Organic Chemistry,
Год журнала:
2022,
Номер
11(8)
Опубликована: Май 12, 2022
Abstract
A
reliable
method
for
preparing
P
(III)‐arylphosphinecarboxamide
derivatives
from
N
‐arylphosphinecarboxamides
and
aryne
precursors
has
been
developed.
This
reaction
was
carried
out
without
transition‐metal
catalysts,
a
series
of
unsymmetrically
structured
phosphinecarboxamide
were
obtained
under
mild
conditions.
In
addition,
the
is
air
atomosphere,
corresponding
P(III)‐aryl
compounds
are
also
stable
in
air.
Advanced Synthesis & Catalysis,
Год журнала:
2023,
Номер
365(22), С. 3849 - 3854
Опубликована: Окт. 18, 2023
Abstract
Herein,
we
report
an
approach
to
phospha‐xanthenes
from
ortho
‐chalcone
based
organophosphines
and
arynes.
These
reactions
proceeded
through
a
sequential
process
consisting
of
formal
[4+2]
cycloaddition,
arylation,
P−OH
formation
P−C
bond
cleavage.
A
gram‐scale
preparation
chemical
conversion
were
performed
demonstrate
the
synthetic
utility
this
method.
Also,
possible
mechanism
was
proposed
on
control
experiments.
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
89(11), С. 8035 - 8040
Опубликована: Май 28, 2024
Mild,
metal-free,
and
operationally
simple
three-component
coupling
reactions
involving
arynes,
phosphites,
acrylates
have
been
achieved.
The
reaction
proceeded
well
with
α-
or
β-substituted
acrylates.
Additionally,
various
functional
groups
were
tolerated
under
these
conditions,
resulting
in
diverse