l–aspartic acid chelan–Cu (II) complex coted on ZrFe2O4 MNPs catalyzed one–pot annulation and cooperative geminal-vinylogous anomeric–based oxidation reactions

Journal of Physics and Chemistry of Solids, Год журнала: 2023, Номер 177, С. 111300 - 111300

Опубликована: Март 2, 2023

Язык: Английский

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Base-Mediated Cascade Lactonization/1,3-Dipolar Cycloaddition Pathway for the One-Pot Assembly of Coumarin-Functionalized Pyrrolo[2,1-a]isoquinolines

The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(12), С. 8420 - 8434

Опубликована: Июнь 5, 2024

An elegant and highly concise strategy for the construction of coumarin-functionalized pyrrolo[2,1-a]isoquinolines from available propargylamines isoquinolinium N-ylides has been disclosed. In this reaction, acted as a C2 synthon to form coumarin ring well 1,3-dipole construct pyrrole in single pot. This cascade process involves 1,4-conjugate addition/lactonization/1,3-dipolar cycloaddition four chemical bonds (one C–O bond three C–C bonds) two new heterocyclic skeletons. Additionally, most these compounds showed good fluorescence properties exhibited high molar extinction coefficient large Stokes shifts.

Язык: Английский

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Review on advancements of pyranopyrazole: synthetic routes and their medicinal applications

Molecular Diversity, Год журнала: 2024, Номер unknown

Опубликована: Янв. 18, 2024

Язык: Английский

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Post-synthetic generation of nanomagnetized tetraaza-copper (II): as a novel heterogeneous catalyst for synthesis of fused N-heterocycles

Research on Chemical Intermediates, Год журнала: 2024, Номер 50(3), С. 1371 - 1391

Опубликована: Фев. 12, 2024

Язык: Английский

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Lewis Acid-Catalyzed 1,4-Addition and Annulation of 4-Hydroxy-coumarins with o-Hydroxyphenyl Propargyl Amines: Entry to Regio-Selective Synthesis of Furano[3,2-c]coumarins and Pyrano[3,2-c]coumarins

The Journal of Organic Chemistry, Год журнала: 2023, Номер 88(7), С. 4730 - 4742

Опубликована: Март 20, 2023

A facile and regioselective Lewis acid-catalyzed cascade annulation of o-hydroxyphenyl propargyl amines with 4-hydroxycoumarin to afford furano[3,2-c]coumarin pyrano[3,2-c]coumarin derivatives is reported. The reaction presumably proceeds by the conjugate addition in situ-generated alkynyl o-quinone methide followed intramolecular 5-exo-dig 6-endo-dig form furano[3,2-c]coumarins pyrano[3,2-c]coumarins, respectively. prepared o-hydroxyl substituted pyrano[3,2-c]coumarins could be readily transformed into corresponding coumarin-derived dioxabicycles acid-mediated cyclization.

Язык: Английский

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Palladium Immobilized on Functionalized Halloysite: A Robust Catalyst for Ligand Free Suzuki–Miyaura Cross Coupling and Synthesis of Pyrano[2,3-c]pyrazole Motifs via Four Component Cascade Reaction and their In-silico Antitubercular Screening

Applied Catalysis A General, Год журнала: 2024, Номер unknown, С. 120003 - 120003

Опубликована: Окт. 1, 2024

Язык: Английский

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Copper-Catalyzed Three-Component Tandem Cyclization for One-Pot Synthesis of Indole-Benzofuran Bis-Heterocycles

The Journal of Organic Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 22, 2024

A one-pot, three-component synthesis of indole-benzofuran bis-heterocycles from terminal alkynes, salicylaldehydes, and indoles has been developed via copper-catalyzed tandem annulation. This catalytic system utilizes readily available starting materials, enabling predictable with broad substrate versatility, excellent regiocontrol, gram-scale amenability. The reaction proceeds a sequential pathway involving A3 coupling, 1,4-conjugate addition, 5-exo-dig cyclization.

Язык: Английский

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Amine-catalyzed metal-free deamination of propargylamines with water toward chalcones

Molecular Catalysis, Год журнала: 2022, Номер 534, С. 112808 - 112808

Опубликована: Ноя. 18, 2022

Язык: Английский

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Modular synthesis of conjugated enamidines and cascade annulation toward benzofuran-3-oxoacetate

Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(7), С. 2047 - 2053

Опубликована: Янв. 1, 2024

A three-component reaction of aryne, DMF and isonitrile for the synthesis otherwise inaccessible chemotype, conjugated enamidines, is developed. Incubation with a Brønsted acid causes cascade skeleton rearrangement enamidines to benzofuran-3-oxoacetates.

Язык: Английский

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Recent Highlights in the Synthesis and Biological Significance of Pyrazole Derivatives

Heliyon, Год журнала: 2024, Номер 10(20), С. e38894 - e38894

Опубликована: Окт. 1, 2024

Язык: Английский

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