Electrochemical oxidation-induced diazolation of alkenes to build N,N′-ethylene-bridged bispyrazole derivatives DOI
Shuai Liu,

Lei Ju,

Xirun Wang

и другие.

Tetrahedron, Год журнала: 2023, Номер 148, С. 133707 - 133707

Опубликована: Окт. 19, 2023

Язык: Английский

Efficient Synthesis of Fully Substituted and Diversely Functionalized Pyrazoles through p‐TSA Catalyzed One‐Pot Condensation of Cyclic β‐Diketones, Arylglyoxals and Arylhydrazones DOI

Arun Dhurey,

Subhro Mandal,

Animesh Pramanik

и другие.

European Journal of Organic Chemistry, Год журнала: 2023, Номер 26(40)

Опубликована: Авг. 29, 2023

Abstract A one‐pot, three‐component, and atom economic synthesis of biologically pharmaceutically important fully substituted functionalized pyrazole derivatives has been accomplished under metal‐catalyst‐free benign conditions. The strategy involves early condensation readily available cyclic β ‐diketones (dimidone, 4‐hydroxycoumarin 2‐hydroxy‐1,4‐naphthoquinone) arylglyoxals to generate a chalcone type intermediate which upon acid catalyzed with ambident nucleophile arylhydrazones produces various aryl ‐diketone derivatives. embraces high functional group tolerance, broad substrate scope, excellent yield the products, short reaction time operationally simple mild provides an easy opportunity incorporating N‐diarylsulfide/selenide functionality, enolisable other bioactive heterocycles concurrently pyrazole, may help in designing development pharmacological significance.

Язык: Английский

Процитировано

3
Development of a simple and safe route to C-3 arylated 1H-pyrazoles DOI
Dengke Li

Tetrahedron Letters, Год журнала: 2024, Номер 152, С. 155356 - 155356

Опубликована: Ноя. 1, 2024

Язык: Английский

Процитировано

0
Electrocyclization for the Synthesis of Mono‐ and Disulfonyl‐substituted Pyrazoles From Sulfonyl Hydrazines and 1,3‐Diketones DOI
Yuanyuan Wu,

Qiping Liu,

Zhitao Ning

и другие.

ChemistrySelect, Год журнала: 2024, Номер 9(45)

Опубликована: Ноя. 26, 2024

Abstract The tunable electrocyclic reactions for the synthesis of a series mono‐ and disulfonyl‐substituted pyrazoles from sulfonyl hydrazines 1,3‐diketones were investigated by utilizing inexpensive electrolytes under electrochemical conditions in an undivided cell. When n Bu 4 NBF was used as electrolyte, it afforded monosulfonyl‐substituted pyrazoles. By contrast, when NH I gave mechanistic investigation shows that they all underwent free radical process but formed N ‐centered hydrazine S‐centered pyrazoles, respectively.

Язык: Английский

Процитировано

0
Recent advances in electrooxidative radical/radical cross-coupling DOI

Pingsen Shi,

Hong Yi, Aiwen Lei

и другие.

Chinese Science Bulletin (Chinese Version), Год журнала: 2023, Номер 68(30), С. 3926 - 3941

Опубликована: Май 24, 2023

Язык: Английский

Процитировано

0
Electrochemical oxidation-induced diazolation of alkenes to build N,N′-ethylene-bridged bispyrazole derivatives DOI
Shuai Liu,

Lei Ju,

Xirun Wang

и другие.

Tetrahedron, Год журнала: 2023, Номер 148, С. 133707 - 133707

Опубликована: Окт. 19, 2023

Язык: Английский

Процитировано

0