Pd-Catalyzed Direct Diarylation of Sodium Hypophosphite Enables the Synthesis of Diarylphosphonates

Molecules, Год журнала: 2025, Номер 30(7), С. 1564 - 1564

Опубликована: Март 31, 2025

A facile and efficient method for synthesizing diarylphosphinates from alcohols aryl halides, using stable, green, readily available sodium hypophosphite as a phosphorus source, is disclosed herein the first time. This offers high-efficiency excellent functional group tolerance, providing straightforward approach to broad range of green starting materials with moderate yields.

Язык: Английский

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Environmentally friendly strategy for the direct conversion of sodium hypophosphite into organophosphorus compounds

Green Synthesis and Catalysis, Год журнала: 2025, Номер unknown

Опубликована: Март 1, 2025

Язык: Английский

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Nickel-Catalyzed Asymmetric Synthesis of Ambiphilic Secondary Phosphine Oxides

Journal of the American Chemical Society, Год журнала: 2025, Номер unknown

Опубликована: Апрель 16, 2025

The synthesis of ambiphilic compounds, which possess both strong nucleophilic and electrophilic functional groups, presents a significant challenge due to their propensity self-react, forming oligomers or polymers. We have successfully achieved the nickel-catalyzed asymmetric P-stereogenic alkenyl secondary phosphine oxides from tailored primary oxide by leveraging controversial stability reactivity. This method demonstrates remarkable tolerance toward wide range unactivated alkynes, including those derived natural products medicinally relevant molecules, thus providing universal synthon for phosphines with high enantioselectivity regioselectivity. product exhibits interesting orthogonal reactivities nucleophiles electrophiles can be easily converted variety compounds.

Язык: Английский

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Bridging Homogeneous and Heterogeneous Catalysis: Ni@CPOL-dppp&PPh₃-Catalyzed Symmetric H-Phosphonate Diester Synthesis from Sodium Hypophosphite

ACS Catalysis, Год журнала: 2025, Номер unknown, С. 7912 - 7918

Опубликована: Апрель 29, 2025

Язык: Английский

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Synthesis of β-Hydroxyhydrophosphonic Acids from Inorganic Sodium Hypophosphite

Synthesis, Год журнала: 2023, Номер 56(11), С. 1677 - 1686

Опубликована: Июль 19, 2023

Abstract An efficient approach to access β-hydroxyhydrophosphonic acid derivatives is reported by ring-opening reaction of readily available epoxides with green, inexpensive, and safe inorganic salt sodium hypophosphate as the phosphorus source in presence silver trifluoromethanesulfonate catalyst. The achieved under simple operation exhibits excellent selectivity well good functional group compatibility.

Язык: Английский

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Recovery of Elemental Arsenic from Acidic As-Containing Wastewater by a Hypophosphite Reduction Process

Water, Год журнала: 2024, Номер 16(9), С. 1301 - 1301

Опубликована: Май 2, 2024

Biological oxidation is a low-carbon technology for the treatment of As-containing gold ores, but it causes large amount acidic wastewater that harmful to environment. This paper proposed novel, eco-friendly method treat this wastewater. Thermodynamic analysis, H2PO2− reduction, and recycling tests were conducted. analysis indicates feasibility reduction As(V)/As(III) by or H3PO2 As0 under conditions. Experimental results confirmed thermodynamic prediction showed could efficiently convert As (i.e., As(V)/As(III)) in high value-added As0. Under optimal conditions, 99.61% precipitated out, obtained had purity 98.5%. Kinetic reaction order concentration was 0.6399, activation energy process 34.33 kJ/mol, which indicative mixed-controlled (20–40 kJ/mol). Wastewater after recovering As, be reused as bacterial culture medium. Based on experimental analytical results, hypophosphite mechanisms removing from its proposed. The presented suggest one-step approach, may promising treating

Язык: Английский

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Transition metal-catalyzed P(O)-H alkenylation, allenylation and alkynylation reactions: a recent trend

Tetrahedron, Год журнала: 2024, Номер unknown, С. 134388 - 134388

Опубликована: Ноя. 1, 2024

Язык: Английский

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Advances in Mechanistic Studies of Metal-Catalyzed Hydrophosphinylation of Non-Activated Alkynes

Chinese Journal of Organic Chemistry, Год журнала: 2024, Номер 44(12), С. 3678 - 3678

Опубликована: Янв. 1, 2024

Язык: Английский

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Regioselective Synthesis of β-Silyl-Substituted Vinylphosphine Oxides via Copper-Catalyzed Protosilylation of Dialkynylphosphine Oxides

Chinese Journal of Organic Chemistry, Год журнала: 2023, Номер 43(10), С. 3598 - 3598

Опубликована: Янв. 1, 2023

A copper-catalyzed mono-lateral protosilylation of dialkynylphosphine oxides for the synthesis β-silyl substituted vinylphosphine is described.Various (hetero)aryl and alkyl-substituted diynes afforded corresponding products in moderate high yields with chemoselectivity.An alternative alkynyl functional group could also be further derived.

Язык: Английский

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