Synthesis of Alkyl Sulfones via a Photocatalytic Multicomponent Reaction of Aryldiazo Tetrafluoroborate Salts, Styrene Derivatives, and Sodium Metabisulfite DOI
Truong Giang Luu, Hee‐Kwon Kim

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 25, 2024

Practical visible-light-induced synthesis of alkyl sulfones has been achieved via a multicomponent reaction aryldiazo tetrafluoroborate salts, styrene derivatives, thiophenol and sodium metabisulfite in the presence rhodamine B.

Язык: Английский

Photo-Thiocyanoamination of π- and σ-Bonds: Reagent Development and Synthetic Applications DOI
Arunima Mukherjee,

Apurba Samanta,

Soumitra Maity

и другие.

The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Апрель 29, 2025

1,2-Thiocyanoamines make up a class of important structural motifs that are found in number bioactive molecules and precursors to many more. Despite their synthetic significance, expedient access this difunctionalization is rare. Herein, the development thiocyanoimination reagent disclosed, taking advantage photomediated energy transfer phenomena for facile alkenes. The strategy was be viable σ-bonds as well, providing generalized accessing small infused with amine -SCN.

Язык: Английский

Процитировано

0
Photo-Induced Difluoromethylation-Cyclization and Domino Amination-Defluorination to 4-(Aminomethyl)-3-fluoro-quinolinones DOI
Xin Wang, Dongyang Zhao,

Jia-Bo Huang

и другие.

Organic Letters, Год журнала: 2024, Номер unknown

Опубликована: Сен. 30, 2024

Herein, we report a visible light-induced difluoromethylation cyclization and subsequent amination-defluorination reaction. This protocol allows efficient to valuable 3-fluoro-quinolinones in moderate excellent yields. A sequential difluoromethylation-cyclization-amination-defluorination mechanism was proposed based on study. Further density functional theory (DFT) calculations revealed that the base K

Язык: Английский

Процитировано

2
A Chromatographic Relay Conjugated Photoredox Strategy: S, Se- Pharmacophore from Alkenes via Formal [2+2+1] Heteroannulation DOI
Injamam Ul Hoque,

Saradindu Debnath,

Rabindranath Lo

и другие.

Chemical Communications, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

A strategy involving alumina chromatography coupled with photoredox to produce 2-amino-dihydrothiophenes and their selenium analogues via a formal [2+2+1] heteroannulation between alkenes, thio(seleno)cyanate, bromomalonates is reported.

Язык: Английский

Процитировано

2
Visible Light-Induced Copper-Catalyzed Regio- and Stereoselective Difluoroalkylthiocyanation of Alkynes DOI

Xiaoxue Hu,

Yanzhao Wang, Shibo Xu

и другие.

The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(12), С. 9118 - 9124

Опубликована: Июнь 6, 2024

The first regio- and stereoselective difluoroalkylthiocyanation of alkynes with BrCF

Язык: Английский

Процитировано

1
Three-Component Photochemical Cyclization/Dithiocarbamate Formation of gem-Difluoro Quinolin-2(1H)-ones DOI
Fei Chen,

Gangqing Shi,

Yang Zheng

и другие.

Organic Letters, Год журнала: 2024, Номер 26(44), С. 9604 - 9609

Опубликована: Окт. 29, 2024

Herein, a novel visible-light-induced 6-

Язык: Английский

Процитировано

1
Recent Advances in the Synthesis of Organic Thiocyano (SCN) and Selenocyano (SeCN) Compounds, Their Chemical Transformations and Bioactivity DOI Creative Commons
Rodrigo Abonı́a, Daniel Insuasty, Juan‐Carlos Castillo

и другие.

Molecules, Год журнала: 2024, Номер 29(22), С. 5365 - 5365

Опубликована: Ноя. 14, 2024

New approaches for the synthesis of organic thio- and selenocyanates, methods to incorporate them into more complex structures, including a wide variety heterocyclic polycylic derivatives, are reviewed. Protocols that convert SCN SeCN moieties thio seleno derivatives by transforming cyano group also examined. In representative cases, bioactivity data these classes compounds

Язык: Английский

Процитировано

1
Visible-light-induced photocatalytic four-component fluoroalkylation–dithiocarbamylation via difunctionalization of styrenes DOI
Patamawadee Silalai, Rungnapha Saeeng

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер 22(42), С. 8437 - 8452

Опубликована: Янв. 1, 2024

Herein we demonstrate that a visible-light-induced photocatalytic four-component fluoroalkylation-dithiocarbamylation is unified method for the fluoroalkylation of diverse activated fluoroalkyl halides, including monofluoroalkyl bromides, difluoroalkyl trifluoromethyl iodide, and perfluoroalkyl iodides. The synthetic value this has been demonstrated by transformations various substrates containing drug/natural product skeletons, gram scale reactions, further derivatizations fluorodithiocarbamate products. This work features an atom economical protocol simple to operate, does not require any additives or strong bases, can be carried out under mild conditions.

Язык: Английский

Процитировано

0
Visible-light-induced three component difluoromethylation cyclization carbo-thioesterification to CF2-Containing γ-Lactams DOI

Dan Shao,

Tingting Yu,

Lianglong Sun

и другие.

Molecular Catalysis, Год журнала: 2024, Номер 570, С. 114685 - 114685

Опубликована: Ноя. 21, 2024

Язык: Английский

Процитировано

0
Synthesis of Alkyl Sulfones via a Photocatalytic Multicomponent Reaction of Aryldiazo Tetrafluoroborate Salts, Styrene Derivatives, and Sodium Metabisulfite DOI
Truong Giang Luu, Hee‐Kwon Kim

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 25, 2024

Practical visible-light-induced synthesis of alkyl sulfones has been achieved via a multicomponent reaction aryldiazo tetrafluoroborate salts, styrene derivatives, thiophenol and sodium metabisulfite in the presence rhodamine B.

Язык: Английский

Процитировано

0