Divergent Synthesis of Pyrrolidone Fused Pyrimido[1,2-b]indazole through Selective Trapping of Enone Intermediate by 1H-indazol-3-amine DOI

Xi Shen,

Zhi‐Cheng Yu,

You Zhou

и другие.

Chemical Communications, Год журнала: 2024, Номер 60(72), С. 9781 - 9784

Опубликована: Янв. 1, 2024

An oxidant-controlled divergent synthesis of a pyrrolidone fused pyrimido[1,2- b ]indazole skeleton was developed through selective cyclization an in situ generated enone intermediate and 1 H -indazol-3-amine.

Язык: Английский

Divergent Synthesis of Four Types of Fused N‐Containing Heterocycles via Oxidative Multi‐Component Cyclization Reaction DOI Open Access

Xiaoshuang Guo,

Maozhong Miao, Peng Zhao

и другие.

Chinese Journal of Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 31, 2025

Comprehensive Summary An atmospheric‐oxygen‐mediated four‐component reaction was developed for the divergent synthesis of pyrazolo[1,5‐ a ]pyrimidine and pyrazolo[3,4‐ b ]pyridine derivatives from readily available alcohols 3‐aminopyrazoles. In this transformation, atmospheric oxygen serves as green oxidant, promoting equivalent aldehydes four types N ‐containing heterocycles (> 40 examples). Remarkably, transformation features metal‐free molecular diversity.

Язык: Английский

Процитировано

2
Construction of Pyrazolo[1,5-a]pyrimidines and Pyrimido[1,2-b]indazoles with Calcium Carbide as an Alkyne Source DOI

Xinjie You,

Botao Wang, Fei Wen

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер 22(28), С. 5822 - 5826

Опубликована: Янв. 1, 2024

One-step construction of both 5-arylpyrazolo[1,5- a ]pyrimidines and 2-arylpyrimido[1,2- b ]indazoles using inexpensive, abundant easy-to-handle calcium carbide as solid alkyne source is depicted.

Язык: Английский

Процитировано

5
I2–DMSO-mediated formal [3 + 1 + 2] synthesis of pyrimido[1,2-b]indazole using 1,4-dithiane-2,5-diol as a surrogate of ethylene DOI

Yong-Dong Du,

Jungang Wang, Jinyi Liu

и другие.

Tetrahedron Letters, Год журнала: 2025, Номер 156, С. 155453 - 155453

Опубликована: Янв. 9, 2025

Язык: Английский

Процитировано

0
Diastereoselective Double Annulation of Allenoates with Povarov Adducts: Modular Synthesis of Multisubstituted Pyrroloquinolines DOI
Srinivasarao Yaragorla,

Doma Arun

The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(22), С. 16838 - 16849

Опубликована: Ноя. 6, 2024

Herein, we report an atom-economical, one-pot, four-component, diastereoselective double-annulation reaction to construct polyfused pyrroloquinolines. This highlights the cyclization of in situ

Язык: Английский

Процитировано

2
Regioselective synthesis of 3,4-diarylpyrimido[1,2-b]indazole derivatives enabled by iron-catalyzed ring-opening of styrene oxides DOI

Penghui Cao,

Guangping Fan,

Xiaofei Zhao

и другие.

Chemical Communications, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

The first synthesis of 3,4-diarylpyrimido[1,2- b ]indazole derivatives enabled by the epoxide-opening reaction with 3-aminoindazoles has been realized.

Язык: Английский

Процитировано

1
Divergent Synthesis of Pyrrolidone Fused Pyrimido[1,2-b]indazole through Selective Trapping of Enone Intermediate by 1H-indazol-3-amine DOI

Xi Shen,

Zhi‐Cheng Yu,

You Zhou

и другие.

Chemical Communications, Год журнала: 2024, Номер 60(72), С. 9781 - 9784

Опубликована: Янв. 1, 2024

An oxidant-controlled divergent synthesis of a pyrrolidone fused pyrimido[1,2- b ]indazole skeleton was developed through selective cyclization an in situ generated enone intermediate and 1 H -indazol-3-amine.

Язык: Английский

Процитировано

0