31P Nuclear Magnetic Resonance Spectroscopy for Monitoring Organic Reactions and Organic Compounds DOI Creative Commons
João M. Anghinoni,

Irum,

Haroon Ur Rashid

и другие.

The Chemical Record, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 5, 2024

Abstract 31 P NMR spectroscopy is a consolidated tool for the characterization of organophosphorus compounds and, more recently, reaction monitoring. The evolution organic synthesis, mainly due to combination elaborated building blocks with enabling technologies, generated great challenges understand and optimize synthetic methodologies. In this sense, experiments also became routine technique monitoring, accessing products side yields, chiral recognition, kinetic data, intermediates, as well basic parameters, such acid‐base hydrogen‐bonding. This review deals these aspects demonstrating essential role spectroscopy. recent publications (the last ten years) will be explored, discussing strategies accomplished detect and/or quantify distinct molecules, approaching mechanism, stability, stereochemistry, utility probe.

Язык: Английский

Tf2O/DMSO-Promoted Umpolung Phosphorylation for C(sp2)–P or C(sp3)–P Bond Formation DOI
Dawei Shi, Ming Li, R. X. Yang

и другие.

The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Апрель 10, 2025

We have developed an umpolung method utilizing the Tf2O/DMSO-based system for C(sp2)-P bond or C(sp3)-P formation. This employs both P(O)-H and P(O)-OH compounds as phosphorus sources demonstrates excellent compatibility with a wide range of Grignard reagents. Without requirement precious transition metals additives, this one-pot protocol provides practical efficient synthetic pathway to variety aryl alkyl phosphine oxides. The broad substrate scope diverse applications highlight utility method.

Язык: Английский

Процитировано

0
Metal-Free Electrophilic Phosphination with Soft Carbon Nucleophiles: Access to Diverse β-Ketophosphine Oxides DOI
Dawei Shi, Ming Li, Zhichao Wang

и другие.

The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Июнь 2, 2025

A metal-free electrophilic phosphination protocol utilizing silyl enol ethers as soft carbon nucleophiles has been developed under Tf2O/DMSO-mediated conditions. This approach enables convenient access to a diverse range of β-ketophosphine oxides mild reaction The broad substrate scope, scalability, and potential for further synthetic applications highlight the practical utility this method. development method also expands scope umpolung strategies.

Язык: Английский

Процитировано

0
31P Nuclear Magnetic Resonance Spectroscopy for Monitoring Organic Reactions and Organic Compounds DOI Creative Commons
João M. Anghinoni,

Irum,

Haroon Ur Rashid

и другие.

The Chemical Record, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 5, 2024

Abstract 31 P NMR spectroscopy is a consolidated tool for the characterization of organophosphorus compounds and, more recently, reaction monitoring. The evolution organic synthesis, mainly due to combination elaborated building blocks with enabling technologies, generated great challenges understand and optimize synthetic methodologies. In this sense, experiments also became routine technique monitoring, accessing products side yields, chiral recognition, kinetic data, intermediates, as well basic parameters, such acid‐base hydrogen‐bonding. This review deals these aspects demonstrating essential role spectroscopy. recent publications (the last ten years) will be explored, discussing strategies accomplished detect and/or quantify distinct molecules, approaching mechanism, stability, stereochemistry, utility probe.

Язык: Английский

Процитировано

0